Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CGL27_RS44115 Genome accession   NZ_CP022545
Coordinates   10298527..10299192 (+) Length   221 a.a.
NCBI ID   WP_043239878.1    Uniprot ID   -
Organism   Streptomyces sp. 11-1-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 10293527..10304192
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGL27_RS44100 (CGL27_43635) - 10294218..10295579 (-) 1362 WP_078645683.1 dipeptidase -
  CGL27_RS44105 (CGL27_43640) - 10295749..10296954 (+) 1206 WP_078645684.1 geranylgeranyl reductase family protein -
  CGL27_RS44110 (CGL27_43645) - 10297334..10298503 (+) 1170 WP_240451058.1 sensor histidine kinase -
  CGL27_RS44115 (CGL27_43650) vraR 10298527..10299192 (+) 666 WP_043239878.1 response regulator transcription factor Regulator
  CGL27_RS44120 (CGL27_43655) - 10299319..10300251 (-) 933 WP_240450846.1 DUF2797 domain-containing protein -
  CGL27_RS44125 (CGL27_43660) - 10300224..10300466 (-) 243 WP_119993227.1 DUF6332 family protein -
  CGL27_RS44130 (CGL27_43665) - 10300473..10300997 (-) 525 WP_240450847.1 DUF4442 domain-containing protein -
  CGL27_RS44135 (CGL27_43670) - 10301052..10301786 (-) 735 WP_119993230.1 maleylpyruvate isomerase family mycothiol-dependent enzyme -
  CGL27_RS44140 (CGL27_43675) - 10301842..10303068 (-) 1227 WP_240451059.1 MFS transporter -

Sequence

Protein


Download         Length: 221 a.a.        Molecular weight: 23840.71 Da        Isoelectric Point: 4.9970

>NTDB_id=201571 CGL27_RS44115 WP_043239878.1 10298527..10299192(+) (vraR) [Streptomyces sp. 11-1-2]
MIRVALADDQILVRAGFRALLAAQPDIEVVGEAADGEQALALVREQHPDVVLMDIRMPVLDGLAATRRITGDPALGEVKV
VMLTTFELDEYVFEAIRSGASGFLVKDTEPEELLRAVRAVVGGDALLSPGVTRRLIAEFAARSREPAPAAALAELTERER
EVMALVGMGLSNQEIARRLVVSPLTAKTHVSRTMVKLGVRDRAQLVVLAYESGLVRPGWLG

Nucleotide


Download         Length: 666 bp        

>NTDB_id=201571 CGL27_RS44115 WP_043239878.1 10298527..10299192(+) (vraR) [Streptomyces sp. 11-1-2]
GTGATCCGTGTCGCGCTCGCCGATGACCAGATCCTCGTCCGCGCGGGCTTCCGCGCCCTGCTGGCCGCACAGCCGGATAT
CGAGGTGGTCGGCGAGGCGGCCGACGGGGAGCAGGCGCTGGCGCTCGTGCGGGAGCAACACCCCGACGTCGTCCTCATGG
ACATCCGCATGCCGGTGCTCGACGGCCTCGCCGCCACCCGCCGGATCACCGGGGACCCGGCCCTCGGCGAGGTGAAGGTG
GTCATGCTGACCACTTTCGAACTCGATGAGTACGTCTTCGAGGCGATCCGCTCCGGCGCCTCCGGCTTCCTGGTCAAGGA
CACCGAACCGGAAGAGCTGCTGCGGGCGGTGCGCGCGGTCGTCGGCGGCGATGCGCTGCTGTCGCCAGGGGTGACCCGCC
GCCTCATCGCCGAGTTCGCGGCCCGTTCCAGGGAACCCGCGCCCGCGGCGGCGCTGGCGGAGCTGACCGAGCGGGAGCGG
GAGGTGATGGCCCTGGTCGGCATGGGGCTGTCGAACCAGGAGATCGCCCGGCGGCTCGTGGTCAGCCCGCTCACCGCCAA
GACCCATGTGAGCCGCACGATGGTCAAACTGGGCGTCCGGGACCGCGCCCAACTCGTCGTGCTCGCCTATGAGTCGGGCC
TGGTCCGGCCCGGCTGGCTGGGCTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(155-209)

Response regulator receiver domain (Response_reg)

(4-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

39.07

97.285

0.38
  degU Bacillus subtilis subsp. subtilis str. 168

36.889

100

0.376

Multiple sequence alignment