Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CGL27_RS25850 Genome accession   NZ_CP022545
Coordinates   6090223..6090918 (+) Length   231 a.a.
NCBI ID   WP_078642623.1    Uniprot ID   -
Organism   Streptomyces sp. 11-1-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 6085223..6095918
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGL27_RS50210 - 6085502..6086284 (-) 783 WP_162953070.1 hypothetical protein -
  CGL27_RS25830 (CGL27_25525) - 6086310..6086489 (+) 180 WP_119990337.1 CopG family transcriptional regulator -
  CGL27_RS25835 (CGL27_25530) - 6086491..6086835 (+) 345 WP_119990340.1 VOC family protein -
  CGL27_RS25840 (CGL27_25535) - 6086859..6087716 (+) 858 WP_119990342.1 class I SAM-dependent methyltransferase -
  CGL27_RS25845 (CGL27_25540) - 6088808..6090226 (+) 1419 WP_240450634.1 histidine kinase -
  CGL27_RS25850 (CGL27_25545) vraR 6090223..6090918 (+) 696 WP_078642623.1 response regulator transcription factor Regulator
  CGL27_RS25855 (CGL27_25550) - 6091301..6092527 (+) 1227 WP_078642624.1 cytochrome P450 -
  CGL27_RS25860 (CGL27_25555) - 6092675..6094327 (-) 1653 WP_119990345.1 ABC transporter permease -
  CGL27_RS25865 (CGL27_25560) - 6094324..6095241 (-) 918 WP_078642626.1 ABC transporter ATP-binding protein -
  CGL27_RS25870 (CGL27_25565) - 6095334..6095870 (+) 537 WP_119990347.1 MarR family transcriptional regulator -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 24551.32 Da        Isoelectric Point: 4.6286

>NTDB_id=201526 CGL27_RS25850 WP_078642623.1 6090223..6090918(+) (vraR) [Streptomyces sp. 11-1-2]
MTTDVTPPIRVLIADDQVMVREGFSVLLNAQPDIEVVGEAVDGRQAIAQVAALRPDVVLMDIRMPELNGLEATREIVAAD
ADAKVLVLTTFDLDEYVYQALRSGASGFLLKDASARQLGEAVRVVAAGEALLAPTVTKRLITTFTRIGEAAGLGGPLPSP
QGRLAELTERENEVLVLVAQGCSNAEIAARLIVAESTVKTHVSRILVKLGLRDRTQAAVFAYEARLVTPGG

Nucleotide


Download         Length: 696 bp        

>NTDB_id=201526 CGL27_RS25850 WP_078642623.1 6090223..6090918(+) (vraR) [Streptomyces sp. 11-1-2]
ATGACGACCGATGTCACTCCTCCCATCCGCGTGCTGATCGCCGACGACCAGGTGATGGTCCGCGAGGGCTTCTCCGTGCT
GCTGAACGCCCAGCCCGATATCGAGGTCGTCGGCGAGGCGGTCGACGGGCGCCAGGCCATCGCCCAGGTCGCCGCCCTGC
GCCCCGACGTCGTTCTGATGGACATCCGGATGCCGGAGCTCAACGGCCTCGAGGCCACCCGTGAGATCGTCGCGGCGGAC
GCGGACGCCAAGGTGCTCGTCCTGACCACCTTCGATCTGGACGAATACGTCTACCAGGCGTTGCGCTCCGGAGCGAGCGG
CTTCCTGCTCAAGGACGCCTCCGCCCGTCAGCTCGGCGAGGCGGTACGCGTCGTCGCGGCGGGCGAGGCGCTGCTCGCCC
CGACCGTCACCAAGCGTCTGATCACCACCTTCACGCGGATCGGGGAGGCCGCCGGGCTCGGCGGCCCGCTTCCCTCGCCG
CAGGGGCGGCTGGCCGAGCTGACCGAGCGGGAGAACGAGGTGCTGGTGCTGGTAGCCCAGGGCTGCTCCAACGCCGAGAT
CGCCGCGCGGCTGATCGTCGCCGAGTCGACGGTGAAGACGCATGTCAGCCGGATCCTGGTGAAGCTGGGGCTGCGCGACC
GCACCCAGGCGGCGGTGTTCGCGTACGAGGCCCGCCTGGTCACCCCTGGAGGCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(11-122)

Bacterial regulatory proteins, luxR family (GerE)

(167-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.379

94.805

0.411
  degU Bacillus subtilis subsp. subtilis str. 168

43.318

93.939

0.407