Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CGL27_RS16275 Genome accession   NZ_CP022545
Coordinates   3830681..3831358 (+) Length   225 a.a.
NCBI ID   WP_078641194.1    Uniprot ID   A0ABS6CST8
Organism   Streptomyces sp. 11-1-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3825681..3836358
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGL27_RS16255 (CGL27_15960) - 3826222..3826887 (+) 666 WP_119987745.1 TetR family transcriptional regulator -
  CGL27_RS16260 (CGL27_15965) - 3826988..3828193 (+) 1206 WP_119987748.1 alpha/beta hydrolase -
  CGL27_RS16265 (CGL27_15970) - 3828279..3829307 (+) 1029 WP_119987751.1 DUF4429 domain-containing protein -
  CGL27_RS16270 (CGL27_15975) - 3829308..3830684 (+) 1377 WP_119987754.1 sensor histidine kinase -
  CGL27_RS16275 (CGL27_15980) vraR 3830681..3831358 (+) 678 WP_078641194.1 response regulator transcription factor Regulator
  CGL27_RS16280 (CGL27_15985) - 3831484..3832695 (+) 1212 WP_119987757.1 alpha/beta hydrolase -
  CGL27_RS50060 - 3832728..3833012 (+) 285 WP_162952990.1 hypothetical protein -
  CGL27_RS16285 (CGL27_15990) - 3832973..3834016 (-) 1044 WP_119987759.1 aldo/keto reductase -
  CGL27_RS16290 (CGL27_15995) - 3834013..3834474 (-) 462 WP_119987762.1 MerR family transcriptional regulator -
  CGL27_RS16295 (CGL27_16000) - 3834623..3835438 (+) 816 WP_119987765.1 serine hydrolase domain-containing protein -
  CGL27_RS16300 (CGL27_16005) - 3835459..3836127 (-) 669 WP_205587925.1 pirin family protein -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 24288.02 Da        Isoelectric Point: 5.7871

>NTDB_id=201499 CGL27_RS16275 WP_078641194.1 3830681..3831358(+) (vraR) [Streptomyces sp. 11-1-2]
MTIKVIIVDDQAMVRAGFAALLAAQSDIDVVGEAPDGREGVEVSRRAHPDVVLMDVRMPEMDGLEAARQLLDPPRGVIHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLISAVRVVAAGEALLAPSVTRRLIADFARQRPAPRRDGPSARRSG
LTPRETEVLELIARGLSNQEIAESLVLAEQTVKTHIGRVLAKLGLRDRAQAVIFAYESGLVTPGQ

Nucleotide


Download         Length: 678 bp        

>NTDB_id=201499 CGL27_RS16275 WP_078641194.1 3830681..3831358(+) (vraR) [Streptomyces sp. 11-1-2]
ATGACCATCAAGGTGATCATCGTCGACGACCAGGCGATGGTGCGGGCCGGGTTCGCCGCCCTGCTCGCCGCGCAGAGCGA
TATCGACGTCGTCGGCGAGGCGCCCGACGGGCGGGAGGGCGTGGAGGTCAGCCGTCGTGCCCACCCCGATGTGGTGCTGA
TGGACGTCCGGATGCCCGAGATGGACGGGCTCGAGGCGGCGCGGCAACTGCTGGACCCGCCGCGCGGGGTCATCCACCGG
CCCAAGGTCCTGATGCTCACCACCTTCGATGTGGACGACTACGTCTACGAGGCGCTGCGCGCCGGGGCCAGCGGCTTTCT
GCTCAAGGACGCCCCACCGGCCGATCTGATCTCCGCGGTGCGGGTGGTGGCGGCGGGCGAGGCGCTGCTCGCCCCGTCCG
TCACCCGCCGGCTGATCGCCGACTTCGCCCGCCAGCGCCCCGCCCCGCGCCGCGACGGCCCGTCCGCGCGGCGCAGCGGG
CTGACGCCGCGTGAGACCGAGGTGCTGGAGCTGATCGCGCGGGGCCTGTCCAACCAGGAGATCGCCGAGTCGCTGGTGCT
CGCGGAGCAGACGGTGAAGACGCATATCGGCCGGGTGCTGGCCAAGCTGGGGCTGCGCGACCGCGCCCAGGCGGTGATCT
TCGCTTACGAATCGGGCCTGGTGACACCGGGTCAGTAG

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(161-215)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.243

98.667

0.427
  degU Bacillus subtilis subsp. subtilis str. 168

39.207

100

0.396