Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CGL27_RS13145 Genome accession   NZ_CP022545
Coordinates   3135100..3135744 (-) Length   214 a.a.
NCBI ID   WP_119986765.1    Uniprot ID   -
Organism   Streptomyces sp. 11-1-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 3130100..3140744
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGL27_RS13115 (CGL27_12890) - 3130604..3131107 (+) 504 WP_078647326.1 HNH endonuclease -
  CGL27_RS13120 (CGL27_12895) - 3131192..3132151 (-) 960 WP_119986761.1 SPFH domain-containing protein -
  CGL27_RS13125 (CGL27_12900) - 3132304..3132729 (-) 426 WP_059147122.1 NfeD family protein -
  CGL27_RS13130 (CGL27_12905) - 3132812..3133602 (-) 791 Protein_2598 ABC transporter ATP-binding protein -
  CGL27_RS13135 (CGL27_12910) - 3133714..3134517 (+) 804 WP_119986763.1 hypothetical protein -
  CGL27_RS13140 (CGL27_12915) - 3134722..3134961 (-) 240 WP_014059737.1 chaplin -
  CGL27_RS13145 (CGL27_12920) vraR 3135100..3135744 (-) 645 WP_119986765.1 response regulator transcription factor Regulator
  CGL27_RS13150 (CGL27_12925) - 3135737..3136894 (-) 1158 WP_119986767.1 GAF domain-containing sensor histidine kinase -
  CGL27_RS13155 (CGL27_12930) - 3137341..3138084 (+) 744 WP_119986769.1 transglycosylase SLT domain-containing protein -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 23130.52 Da        Isoelectric Point: 5.6857

>NTDB_id=201489 CGL27_RS13145 WP_119986765.1 3135100..3135744(-) (vraR) [Streptomyces sp. 11-1-2]
MADPGRIRVLLVDDHQVVLRGLRTFLQVQDDIEVVGEASDGEEGVARAEELRPDVVLMDVKMPGLDGIEALRTLRDLGNP
ARVLIVTSFTEKRTVVPALRAGAAGYVYKDVDPEALARAIRSVHSGHVLLQPEVALALLSQEEGGGQGRGGSLTEREREV
LALIADGRSNREIARALVLSEKTVKTHVSNILMKLDLADRTQAALWAVRHGIGA

Nucleotide


Download         Length: 645 bp        

>NTDB_id=201489 CGL27_RS13145 WP_119986765.1 3135100..3135744(-) (vraR) [Streptomyces sp. 11-1-2]
GTGGCTGACCCCGGACGGATTCGGGTACTGCTCGTCGACGACCACCAGGTGGTGCTGCGCGGTCTGCGGACCTTTCTCCA
GGTCCAGGACGACATCGAGGTGGTCGGCGAGGCGTCGGACGGCGAGGAGGGCGTCGCCCGCGCCGAGGAGCTGCGCCCCG
ACGTCGTCCTCATGGACGTGAAGATGCCCGGCCTCGACGGCATCGAGGCGCTGCGCACCCTGCGCGACCTCGGCAACCCC
GCCCGGGTGCTGATCGTGACCAGCTTCACCGAGAAGCGCACCGTGGTCCCCGCCCTGCGCGCGGGCGCGGCGGGCTATGT
CTACAAGGACGTGGACCCCGAGGCGCTCGCCCGCGCCATCCGGTCCGTCCACTCCGGGCATGTGCTGCTCCAGCCCGAGG
TGGCCCTGGCGCTGCTCTCCCAGGAGGAGGGCGGCGGTCAGGGGCGCGGCGGCTCACTCACCGAGCGGGAGCGGGAGGTG
CTCGCGCTGATCGCGGACGGCCGGTCCAACCGGGAAATCGCCCGTGCACTGGTGCTGTCCGAAAAGACCGTTAAGACTCA
TGTGTCCAACATTCTTATGAAATTGGATCTCGCCGACCGCACTCAGGCCGCGCTTTGGGCCGTACGGCATGGAATTGGGG
CATGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(9-120)

Bacterial regulatory proteins, luxR family (GerE)

(152-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

44.175

96.262

0.425
  degU Bacillus subtilis subsp. subtilis str. 168

37.838

100

0.393

Multiple sequence alignment