Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CGL27_RS05710 Genome accession   NZ_CP022545
Coordinates   1409048..1409758 (+) Length   236 a.a.
NCBI ID   WP_119985021.1    Uniprot ID   -
Organism   Streptomyces sp. 11-1-2     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1404048..1414758
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CGL27_RS05690 (CGL27_05570) - 1405250..1406581 (-) 1332 WP_240450947.1 FAD-linked oxidase C-terminal domain-containing protein -
  CGL27_RS05695 (CGL27_05575) - 1406833..1407306 (+) 474 WP_119985018.1 nuclear transport factor 2 family protein -
  CGL27_RS05700 (CGL27_05580) - 1407333..1407887 (+) 555 WP_078638768.1 TetR/AcrR family transcriptional regulator -
  CGL27_RS05705 (CGL27_05585) - 1408002..1409051 (+) 1050 WP_240450948.1 histidine kinase -
  CGL27_RS05710 (CGL27_05590) vraR 1409048..1409758 (+) 711 WP_119985021.1 response regulator transcription factor Regulator
  CGL27_RS05715 (CGL27_05595) - 1409876..1411039 (+) 1164 WP_119985023.1 serine hydrolase domain-containing protein -
  CGL27_RS05720 (CGL27_05600) - 1411151..1413682 (-) 2532 WP_119985025.1 ABC transporter permease -
  CGL27_RS05725 (CGL27_05605) - 1413778..1414545 (-) 768 WP_119985027.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 236 a.a.        Molecular weight: 25355.92 Da        Isoelectric Point: 5.1737

>NTDB_id=201477 CGL27_RS05710 WP_119985021.1 1409048..1409758(+) (vraR) [Streptomyces sp. 11-1-2]
MTIRVVVADDQELVRSGFSMILDAQPDIEVIAEAGDGAEAVEAVRRHAPDVALLDIRMPGMDGIEACREIGAEGACRTVM
LTTFDSDEYVYEALHAGASGFLLKDVRRDDLVHAVRVVARGDSLLAPSVARRLVEQYTRATVRPRRPDPRLDMLTARERE
TLLLLARGLSNAEIAAELVVSDHTVKTHVGNVLAKLGLRDRIQAVICAYETGLITAGDPPPGGASRPGSSPASARN

Nucleotide


Download         Length: 711 bp        

>NTDB_id=201477 CGL27_RS05710 WP_119985021.1 1409048..1409758(+) (vraR) [Streptomyces sp. 11-1-2]
TTGACGATCCGTGTGGTGGTGGCCGACGACCAGGAGCTGGTGCGCAGCGGCTTCTCCATGATCCTTGACGCCCAGCCGGA
CATCGAGGTGATCGCGGAGGCGGGCGACGGGGCCGAGGCCGTCGAGGCGGTGCGGCGGCACGCGCCCGATGTGGCGCTGC
TCGACATCCGGATGCCGGGTATGGACGGTATCGAGGCATGCCGCGAGATCGGCGCGGAGGGCGCCTGCCGGACGGTGATG
CTGACGACCTTCGACTCCGATGAGTATGTGTACGAAGCGCTGCACGCGGGCGCGAGCGGCTTCCTGCTGAAGGATGTGCG
CAGGGACGATCTGGTGCACGCGGTACGGGTGGTGGCGCGGGGCGACTCGCTGCTCGCGCCGTCGGTGGCCCGGCGTCTGG
TGGAGCAGTACACCCGGGCGACCGTCCGGCCACGGCGGCCCGATCCCCGCCTGGACATGCTGACCGCACGGGAGCGGGAG
ACACTGCTGCTGCTCGCGCGCGGCCTGTCGAACGCCGAGATCGCGGCGGAGCTGGTGGTCAGCGATCACACGGTCAAGAC
GCATGTCGGCAATGTGCTCGCCAAGCTGGGGCTGCGGGACCGGATTCAGGCGGTGATCTGCGCGTACGAGACGGGCCTGA
TCACGGCCGGGGATCCCCCGCCCGGGGGAGCGTCCCGGCCCGGTTCCTCCCCCGCGTCGGCGAGGAACTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-116)

Bacterial regulatory proteins, luxR family (GerE)

(153-208)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

43.256

91.102

0.394
  degU Bacillus subtilis subsp. subtilis str. 168

39.91

94.492

0.377