Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BKM67_RS08480 Genome accession   NZ_CP017667
Coordinates   1721011..1721700 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain 1081     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1716011..1726700
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM67_RS08455 (BKM67_08275) - 1716482..1717195 (-) 714 Protein_1592 NADPH-dependent oxidoreductase -
  BKM67_RS08460 (BKM67_08280) dnaI 1717192..1718091 (-) 900 WP_105116033.1 primosomal protein DnaI -
  BKM67_RS08465 (BKM67_08285) - 1718091..1719242 (-) 1152 WP_105116032.1 replication initiation/membrane attachment protein -
  BKM67_RS08470 (BKM67_08290) nrdR 1719229..1719720 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  BKM67_RS08475 (BKM67_08295) - 1719791..1720921 (-) 1131 WP_105119183.1 AI-2E family transporter -
  BKM67_RS08480 (BKM67_08300) covR 1721011..1721700 (-) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  BKM67_RS08485 (BKM67_08305) gndA 1721782..1723209 (-) 1428 WP_105119182.1 NADP-dependent phosphogluconate dehydrogenase -
  BKM67_RS08490 (BKM67_08310) - 1723306..1723845 (-) 540 WP_105119181.1 DUF177 domain-containing protein -
  BKM67_RS08495 (BKM67_08315) trxB 1723855..1724772 (-) 918 WP_105119180.1 thioredoxin-disulfide reductase -
  BKM67_RS08500 (BKM67_08320) - 1724785..1725009 (-) 225 WP_002936682.1 DUF4059 family protein -
  BKM67_RS08505 (BKM67_08325) - 1725027..1726370 (-) 1344 WP_105119179.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=201372 BKM67_RS08480 WP_012027645.1 1721011..1721700(-) (covR) [Streptococcus suis strain 1081]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=201372 BKM67_RS08480 WP_012027645.1 1721011..1721700(-) (covR) [Streptococcus suis strain 1081]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAGCAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGACCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATAAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment