Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   BKM67_RS05515 Genome accession   NZ_CP017667
Coordinates   1091265..1092491 (-) Length   408 a.a.
NCBI ID   WP_105183824.1    Uniprot ID   A0AAD0P8M7
Organism   Streptococcus suis strain 1081     
Function   require for competence development (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1049517..1098362 1091265..1092491 within 0


Gene organization within MGE regions


Location: 1049517..1098362
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BKM67_RS05290 (BKM67_05190) xerS 1049517..1050587 (-) 1071 WP_105115640.1 tyrosine recombinase XerS -
  BKM67_RS05295 (BKM67_05195) - 1050760..1051284 (-) 525 WP_105119906.1 AAA family ATPase -
  BKM67_RS05300 (BKM67_05200) - 1051349..1052089 (-) 741 WP_105119907.1 DUF3307 domain-containing protein -
  BKM67_RS05305 (BKM67_05205) - 1052094..1052762 (-) 669 WP_029171776.1 SatD family protein -
  BKM67_RS05310 (BKM67_05210) ffh 1052956..1054530 (-) 1575 WP_024388685.1 signal recognition particle protein -
  BKM67_RS05315 (BKM67_05215) - 1054543..1054875 (-) 333 WP_002935001.1 putative DNA-binding protein -
  BKM67_RS05320 (BKM67_05220) - 1054977..1055675 (-) 699 WP_105184252.1 GntR family transcriptional regulator -
  BKM67_RS05325 (BKM67_05225) guaA 1055951..1057501 (+) 1551 WP_105184253.1 glutamine-hydrolyzing GMP synthase -
  BKM67_RS05330 (BKM67_05230) - 1058196..1058474 (-) 279 WP_024407057.1 helix-turn-helix transcriptional regulator -
  BKM67_RS05335 - 1058647..1058907 (-) 261 Protein_987 topoisomerase DNA-binding C4 zinc finger domain-containing protein -
  BKM67_RS05345 (BKM67_05235) erm(B) 1059077..1059814 (-) 738 WP_010725416.1 23S rRNA (adenine(2058)-N(6))-methyltransferase Erm(B) -
  BKM67_RS05350 - 1059939..1060007 (-) 69 WP_105117102.1 23S rRNA methyltransferase attenuation leader peptide -
  BKM67_RS05355 (BKM67_05240) - 1060099..1060305 (+) 207 WP_024406352.1 helix-turn-helix domain-containing protein -
  BKM67_RS05360 (BKM67_05245) - 1060330..1061631 (-) 1302 WP_024406351.1 hypothetical protein -
  BKM67_RS05365 (BKM67_05250) - 1061885..1062193 (+) 309 WP_024417958.1 hypothetical protein -
  BKM67_RS05370 (BKM67_05255) - 1062216..1062740 (+) 525 WP_024415777.1 hypothetical protein -
  BKM67_RS05375 (BKM67_05260) - 1063249..1064487 (+) 1239 WP_105184221.1 Rep family protein -
  BKM67_RS05380 (BKM67_05265) - 1064465..1064698 (+) 234 WP_050573319.1 DUF3173 domain-containing protein -
  BKM67_RS05385 (BKM67_05270) - 1064670..1065980 (+) 1311 WP_024417955.1 site-specific integrase -
  BKM67_RS05390 (BKM67_05275) mcrC 1066237..1067286 (-) 1050 WP_044776258.1 5-methylcytosine-specific restriction endonuclease system specificity protein McrC -
  BKM67_RS05395 (BKM67_05280) - 1067283..1068980 (-) 1698 WP_105184220.1 AAA family ATPase -
  BKM67_RS05400 (BKM67_05285) - 1069176..1069964 (+) 789 WP_044667751.1 hypothetical protein -
  BKM67_RS05405 (BKM67_05290) - 1069992..1070939 (+) 948 WP_161948745.1 hypothetical protein -
  BKM67_RS05410 (BKM67_05295) - 1070960..1071313 (-) 354 WP_024408909.1 HIRAN domain-containing protein -
  BKM67_RS05415 (BKM67_05300) - 1071335..1072090 (-) 756 WP_029171783.1 DUF6287 domain-containing protein -
  BKM67_RS05420 (BKM67_05305) - 1072107..1072865 (-) 759 WP_015646851.1 SDR family NAD(P)-dependent oxidoreductase -
  BKM67_RS11055 (BKM67_05310) - 1072983..1077971 (-) 4989 WP_239495101.1 starch-binding protein -
  BKM67_RS05435 (BKM67_05315) - 1078400..1079524 (+) 1125 Protein_1005 ISL3 family transposase -
  BKM67_RS05440 (BKM67_05320) - 1079525..1080007 (-) 483 Protein_1006 lysozyme family protein -
  BKM67_RS05445 (BKM67_05325) - 1080008..1080982 (-) 975 WP_015646852.1 nucleoid-associated protein -
  BKM67_RS05450 (BKM67_05330) glyA 1080982..1082241 (-) 1260 WP_014637944.1 serine hydroxymethyltransferase -
  BKM67_RS05455 (BKM67_05335) - 1082265..1082696 (-) 432 WP_105140174.1 GNAT family N-acetyltransferase -
  BKM67_RS05460 (BKM67_05340) - 1082693..1083301 (-) 609 WP_105140175.1 L-threonylcarbamoyladenylate synthase -
  BKM67_RS05465 (BKM67_05345) prmC 1083288..1084121 (-) 834 WP_105183821.1 peptide chain release factor N(5)-glutamine methyltransferase -
  BKM67_RS05470 (BKM67_05350) prfA 1084121..1085200 (-) 1080 WP_015646857.1 peptide chain release factor 1 -
  BKM67_RS05475 (BKM67_05355) - 1085480..1086061 (-) 582 WP_012028098.1 thymidine kinase -
  BKM67_RS05485 (BKM67_05365) - 1086444..1087622 (-) 1179 WP_238145573.1 excalibur calcium-binding domain-containing protein -
  BKM67_RS05490 (BKM67_05370) - 1087886..1088068 (+) 183 WP_044670667.1 4-oxalocrotonate tautomerase -
  BKM67_RS05495 (BKM67_05375) lepA 1088118..1089950 (-) 1833 WP_024383525.1 translation elongation factor 4 -
  BKM67_RS05505 (BKM67_05380) ndk 1090188..1090601 (-) 414 WP_105183823.1 nucleoside-diphosphate kinase -
  BKM67_RS05510 (BKM67_05385) yihA 1090624..1091211 (-) 588 WP_014638915.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  BKM67_RS05515 (BKM67_05390) clpX 1091265..1092491 (-) 1227 WP_105183824.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  BKM67_RS05525 (BKM67_05400) - 1092689..1093201 (-) 513 WP_029171792.1 dihydrofolate reductase -
  BKM67_RS05530 (BKM67_05405) - 1093498..1094337 (-) 840 WP_105183825.1 thymidylate synthase -
  BKM67_RS05535 (BKM67_05410) - 1094389..1094691 (-) 303 WP_044679582.1 hypothetical protein -
  BKM67_RS05540 (BKM67_05415) - 1094703..1094981 (-) 279 WP_002934968.1 hypothetical protein -
  BKM67_RS05545 (BKM67_05420) - 1095107..1096066 (-) 960 WP_014637956.1 ROK family glucokinase -
  BKM67_RS05550 (BKM67_05425) - 1096158..1096493 (-) 336 WP_105183826.1 hypothetical protein -
  BKM67_RS05555 (BKM67_05430) - 1096494..1098362 (-) 1869 WP_105183827.1 ABC-F family ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45282.80 Da        Isoelectric Point: 4.5987

>NTDB_id=201357 BKM67_RS05515 WP_105183824.1 1091265..1092491(-) (clpX) [Streptococcus suis strain 1081]
MAVKHTQELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDESDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=201357 BKM67_RS05515 WP_105183824.1 1091265..1092491(-) (clpX) [Streptococcus suis strain 1081]
ATGGCTGTCAAGCATACACAAGAGCTTATCTATTGCTCATTTTGTGGTAAAAACCAAGAAGAAGTTAAAAAAATTATTGC
AGGAAATAATGTTTTCATTTGTAATGAGTGTGTTGAGTTAGCTCAAGAAATCATTCGTGAAGAATTGGCTGAAGAAGTAC
TGACAGATTTGGCAGACACACCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAGGATAGCCGTGATGAGAGCGATGTTGA
TTTGCAAAAATCAAATATCCTTATGATTGGTCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACCTTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTCCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCAAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTTATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATCATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATATCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGCCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAACCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment