Detailed information NTG0201327

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: BKM66_RS10305
• Genome accession: NZ_CP017666
• Coordinates: 2136197..2137393 (+)
• Length: 398 a.a.
• NCBI ID: WP_044668907.1
• Uniprot ID: A0AAD0KWB0
• Organism: Streptococcus suis strain 0061
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2131197..2142393

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BKM66_RS10265 (BKM66_10010)	-	2131514..2132752 (+)	1239	WP_105183997.1	replication initiation factor domain-containing protein	-
BKM66_RS10270 (BKM66_10015)	-	2132809..2133147 (+)	339	WP_105183998.1	DUF771 domain-containing protein	-
BKM66_RS10275 (BKM66_10020)	-	2133210..2134331 (+)	1122	WP_105183999.1	site-specific integrase	-
BKM66_RS10295 (BKM66_10040)	-	2134836..2135519 (-)	684	WP_105184000.1	YoaK family protein	-
BKM66_RS10300 (BKM66_10045)	rlmH	2135544..2136023 (-)	480	WP_105184001.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
BKM66_RS10305 (BKM66_10050)	htrA	2136197..2137393 (+)	1197	WP_044668907.1	trypsin-like peptidase domain-containing protein	Regulator
BKM66_RS10310 (BKM66_10055)	spo0J	2137454..2138218 (+)	765	WP_044693492.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41838.88 Da
• Isoelectric Point: 4.5454

>NTDB_id=201327 BKM66_RS10305 WP_044668907.1 2136197..2137393(+) (htrA) [Streptococcus suis strain 0061]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSTITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYVVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSVYANTVTQGIISSLSRTVTSQSEDGQTISTNAIQTDTAINPGNSGGPLIN
IQGQVIGITSSKITSSSVSSSGVAVEGMGFAIPANDAVAIINQLEKAGKVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGETIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=201327 BKM66_RS10305 WP_044668907.1 2136197..2137393(+) (htrA) [Streptococcus suis strain 0061]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAACCACAGGTTCAACAAGCAAATTCTACTATCACTAGTGTCAGCAATGTTCAATACA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCC
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCTGTTGCTGGAGAGGGGTCTGGGGTTAT
CTATAAAAAAGATGGTCAATATGCCTATGTTGTGACAAATACGCATGTCATTAATAACGCAGAAAAGATTGATATTCTTT
TAGCATCTGGAGAAAAAATCAGCGGTGAACTCGTTGGTTCCGATACCTATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGTAGCGTCTACGCTAATACAGTTACTCAAGGTATTATTTCTAGCCTAAGTCGGACAGTTACTTCACAATCAGAAG
ATGGTCAAACAATCTCAACCAACGCTATTCAAACCGATACGGCTATCAACCCCGGAAACTCTGGAGGACCATTGATTAAT
ATCCAAGGACAAGTTATTGGTATCACCTCTAGCAAAATCACCTCAAGTTCTGTAAGTAGCTCAGGTGTGGCTGTAGAAGG
GATGGGATTTGCTATTCCTGCAAATGATGCCGTAGCCATTATCAATCAACTTGAGAAAGCTGGAAAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTGGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTCATTACTGA
GATTGACGGAGAAACTATTCAAAATAAGAGTGATCTCCAAAGCGCTCTCTACAAACATCAAATTGGAGACACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	60.453	99.749	0.603
htrA	Streptococcus gordonii str. Challis substr. CH1	60.506	99.246	0.6
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565