Detailed information NTG0201000

Bioinformatically predicted

Overview

• Name: hexA
• Type: Machinery gene
• Locus tag: CG450_RS12750
• Genome accession: NZ_CP022477
• Coordinates: 2400976..2403585 (-)
• Length: 869 a.a.
• NCBI ID: WP_011197985.1
• Uniprot ID: Q65JE2
• Organism: Bacillus licheniformis strain BL-010
• Function: DNA mismatch repair (predicted from homology) Homologous recombination

Genomic Context

Location: 2395976..2408585

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CG450_RS12725	-	2396986..2397423 (-)	438	WP_011201654.1	hypothetical protein	-
CG450_RS12730	-	2397479..2397727 (-)	249	WP_080508521.1	HNH/endonuclease VII fold putative polymorphic toxin	-
CG450_RS12735	-	2397724..2398251 (-)	528	WP_003181977.1	pre-toxin TG domain-containing protein	-
CG450_RS12740	-	2398433..2398714 (-)	282	WP_003181975.1	putative quinol monooxygenase	-
CG450_RS12745	hexB	2399048..2400958 (-)	1911	WP_003181972.1	DNA mismatch repair endonuclease MutL	Machinery gene
CG450_RS12750	hexA	2400976..2403585 (-)	2610	WP_011197985.1	DNA mismatch repair protein MutS	Machinery gene
CG450_RS12755	cotE	2403696..2404244 (-)	549	WP_003181968.1	outer spore coat protein CotE	-
CG450_RS12760	ymcA	2404487..2404918 (-)	432	WP_003181967.1	RicAFT regulatory complex protein RicA family protein	Regulator
CG450_RS12765	miaB	2404920..2406449 (-)	1530	WP_003181965.1	tRNA (N6-isopentenyl adenosine(37)-C2)-methylthiotransferase MiaB	-
CG450_RS12770	-	2406593..2407768 (-)	1176	WP_009328481.1	glycine C-acetyltransferase	-

Sequence

Protein

• Length: 869 a.a.
• Molecular weight: 98514.94 Da
• Isoelectric Point: 5.3661

>NTDB_id=201000 CG450_RS12750 WP_011197985.1 2400976..2403585(-) (hexA) [Bacillus licheniformis strain BL-010]
MAGYTPMIQQYLKIKAEYQDAFLFFRLGDFYEMFFEDAKKASQELEITLTSRDGGSSERIPMCGVPYHSCSSYIEQLIKK
GYKVAICEQVEDPKSAKGVVKREVVQLITPGTVMDGKGIHENENNFIASVSKFQHTYGLAFSDLTTGENLVTAIERLDDV
VSEIYSVGAREIVVSRNLDEKDVAMLKERCGATISFEDEQADEVPGIVNGLGSKELVDTFMRLYVYLKRTQKRSLDHLQN
VQAYELEEAMKIDLYSKRNLELTETIRSKNKKGSLLWLLDETKTAMGGRLLKQWIDRPLIRKGQIEERQEIVETLIAHLF
EREDLRERLKEVYDLERLAGRVAYGNVNARDLIQLKESLKQVPAIKQLVGSLDHPKAKARAEKIDPCGDLLNLLEDALYE
NPPLSLKEGNLIKDGYHAKLDEYRDASKNGKDWIARLEQQEREYTGIRSLKVGFNKVFGYYIEVTKANIHLLEEGRYERK
QTLTNAERYITPELKEKEALILEAENNICELEYELFSELRSKVKEYIPRLQQLAKMMSELDVLQCFATISENRHYVKPEF
SDDVVQVIDGRHPVVEKVMDSQSYVPNSCEMGKGRQMLLITGPNMSGKSTYMRQMALISILAQIGCFVPAKKAVLPIFDQ
IFTRIGAADDLISGQSTFMVEMLEAKNAIVHATKNSLILFDEIGRGTSTYDGMALAQAIIEYVHEHIGAKTLFSTHYHEL
TSLEEKLDDLKNVHVRAEEYEGKVVFLHQIKEGAADKSYGIHVAQLAELPDGLISRAKTILKELESGAKEAAPSTAPNMV
KEAAEEAAATVADQPAQLSFFETDKPIEKETKLSKKEQAVLAEFKAMDLLDMTPIQVMNELYRLQKKLK

Nucleotide

• Length: 2610 bp

>NTDB_id=201000 CG450_RS12750 WP_011197985.1 2400976..2403585(-) (hexA) [Bacillus licheniformis strain BL-010]
ATGGCAGGCTACACGCCTATGATACAGCAATATTTAAAGATTAAGGCAGAGTATCAGGATGCCTTTTTATTTTTTCGTCT
TGGCGACTTTTATGAGATGTTTTTTGAAGATGCAAAAAAGGCGTCTCAGGAGCTCGAAATCACGCTGACGAGCAGGGACG
GAGGATCAAGCGAAAGAATCCCGATGTGCGGGGTTCCTTATCATTCCTGCTCTTCGTATATCGAACAGCTCATTAAAAAA
GGCTATAAAGTCGCGATCTGTGAACAGGTGGAGGACCCTAAATCGGCCAAAGGAGTCGTCAAAAGGGAAGTCGTGCAGCT
GATCACACCCGGCACCGTGATGGACGGCAAAGGGATTCATGAAAATGAAAACAACTTTATCGCCTCTGTCAGTAAATTTC
AGCATACATACGGGCTCGCTTTTTCTGATTTGACGACGGGCGAGAATTTAGTAACGGCTATCGAAAGGCTTGATGATGTC
GTTTCCGAGATTTACTCTGTCGGAGCAAGGGAAATCGTCGTCAGCCGCAACCTTGACGAGAAAGACGTCGCAATGCTGAA
AGAGCGCTGCGGCGCCACGATCTCTTTCGAGGATGAACAAGCGGATGAAGTGCCTGGCATTGTGAACGGACTGGGGTCCA
AAGAGCTTGTCGATACGTTTATGAGGCTTTACGTCTACTTGAAGCGGACGCAGAAAAGAAGCCTCGACCACCTTCAAAAC
GTTCAGGCCTACGAGCTCGAAGAAGCGATGAAAATCGATTTGTACTCGAAACGCAATCTTGAACTGACGGAAACGATCCG
TTCGAAAAACAAAAAAGGCTCGCTTCTTTGGCTTTTGGATGAAACGAAAACGGCCATGGGAGGGCGGCTGTTAAAGCAAT
GGATCGACAGGCCGCTGATCAGAAAGGGACAGATCGAAGAGCGCCAGGAAATCGTTGAAACGCTGATCGCCCATCTGTTT
GAGCGGGAAGATTTGCGCGAACGGCTGAAGGAAGTATACGACCTCGAGCGGCTCGCCGGAAGGGTCGCATACGGCAACGT
CAACGCCAGAGATTTGATCCAGCTGAAGGAATCGCTGAAACAAGTCCCGGCCATCAAACAGCTTGTCGGCTCCCTCGACC
ATCCGAAAGCAAAAGCGCGCGCCGAGAAAATCGATCCGTGCGGCGATCTTTTGAATCTTTTGGAAGACGCGCTATACGAG
AATCCGCCTCTTTCATTAAAAGAGGGGAACTTAATCAAAGACGGCTACCACGCGAAACTGGATGAATACAGGGACGCAAG
CAAGAACGGAAAAGACTGGATCGCAAGGCTTGAGCAGCAGGAACGCGAGTACACGGGAATCCGCTCTTTAAAAGTCGGCT
TTAACAAGGTGTTCGGCTATTATATTGAAGTGACGAAAGCGAACATCCATCTGCTTGAAGAAGGCCGCTATGAACGGAAG
CAGACGCTGACCAATGCAGAACGCTACATCACGCCGGAGCTGAAAGAAAAAGAAGCCCTGATTCTCGAAGCGGAAAACAA
TATTTGCGAGCTGGAGTATGAGCTGTTTTCCGAGCTTCGCAGCAAGGTGAAGGAATATATCCCGCGCTTGCAGCAGCTGG
CAAAAATGATGAGCGAGCTTGATGTGCTCCAATGTTTTGCGACGATCAGCGAAAACCGGCACTATGTTAAGCCGGAGTTT
TCCGATGATGTCGTTCAGGTGATCGACGGACGGCATCCGGTCGTAGAAAAGGTGATGGACAGCCAGTCTTACGTTCCGAA
CAGCTGTGAAATGGGCAAAGGCAGGCAGATGCTTTTAATCACCGGGCCGAATATGTCCGGGAAAAGCACGTATATGAGAC
AGATGGCGCTGATCTCCATTTTGGCGCAGATCGGCTGCTTTGTTCCTGCGAAAAAAGCGGTGCTGCCGATCTTTGATCAG
ATCTTTACGAGAATTGGCGCAGCGGATGATCTTATATCCGGACAGAGCACGTTTATGGTGGAAATGCTTGAAGCCAAAAA
CGCGATCGTCCATGCGACGAAAAACAGCTTGATTTTATTTGACGAAATCGGCCGGGGTACGTCCACTTACGACGGAATGG
CGCTTGCACAAGCGATCATCGAGTACGTTCACGAGCACATCGGCGCGAAGACTTTATTTTCCACTCACTACCACGAGCTG
ACGTCCCTTGAAGAAAAGCTGGACGATTTGAAGAATGTCCACGTTCGTGCGGAAGAATACGAAGGAAAGGTCGTTTTCCT
TCACCAGATAAAAGAAGGAGCAGCAGATAAAAGCTACGGTATCCATGTCGCGCAGCTGGCTGAATTGCCCGACGGTTTGA
TCAGCAGGGCGAAAACGATCCTGAAAGAACTTGAATCCGGCGCAAAAGAAGCCGCTCCATCAACGGCACCGAATATGGTA
AAAGAGGCGGCGGAAGAAGCCGCGGCGACTGTTGCAGATCAACCGGCCCAGCTGTCATTTTTTGAGACGGACAAGCCAAT
AGAAAAAGAGACGAAGCTCTCCAAAAAAGAGCAGGCTGTTTTAGCCGAATTTAAAGCGATGGATCTGCTCGATATGACGC
CTATACAAGTCATGAATGAACTGTACAGGCTGCAAAAAAAATTAAAGTAA

Domains

Predicted by InterProScan.

• MutS domain V (MutS_V) (598-785)

• MutS domain III (MutS_III) (258-547)

• MutS domain I (MutS_I) (5-116)

• MutS domain II (MutS_II) (125-239)

• MutS family domain IV (MutS_IV) (415-506)

3D structure

• AlphaFold DB: Q65JE2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
hexA	Streptococcus pneumoniae R6	49.017	99.54	0.488
mutS	Pseudomonas stutzeri strain ATCC 17587	37.528	100	0.381