Detailed information NTG0200655

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: CGZ53_RS00360
• Genome accession: NZ_CP022435
• Coordinates: 61558..62472 (+)
• Length: 304 a.a.
• NCBI ID: WP_249630218.1
• Uniprot ID: -
• Organism: Streptococcus uberis strain NZ01
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 56558..67472

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
CGZ53_RS00340 (CGZ53_00340)	purD	56977..58239 (+)	1263	WP_100911828.1	phosphoribosylamine--glycine ligase	-
CGZ53_RS00345 (CGZ53_00345)	purE	58285..58773 (+)	489	WP_012657620.1	5-(carboxyamino)imidazole ribonucleotide mutase	-
CGZ53_RS00350 (CGZ53_00350)	purK	58760..59833 (+)	1074	WP_046389804.1	5-(carboxyamino)imidazole ribonucleotide synthase	-
CGZ53_RS00355 (CGZ53_00355)	purB	60147..61439 (+)	1293	WP_012657622.1	adenylosuccinate lyase	-
CGZ53_RS00360 (CGZ53_00360)	comR	61558..62472 (+)	915	WP_249630218.1	helix-turn-helix domain-containing protein	Regulator
CGZ53_RS09490	-	62571..62669 (+)	99	WP_198433762.1	quorum-sensing system DWW-type pheromone	-
CGZ53_RS00365 (CGZ53_00365)	ruvB	62701..63705 (+)	1005	WP_012657625.1	Holliday junction branch migration DNA helicase RuvB	Machinery gene
CGZ53_RS00370 (CGZ53_00370)	-	63956..64384 (+)	429	WP_012657626.1	low molecular weight protein-tyrosine-phosphatase	-
CGZ53_RS00375 (CGZ53_00375)	-	64389..64802 (+)	414	WP_012657627.1	membrane protein	-
CGZ53_RS00380 (CGZ53_00380)	-	64799..66577 (+)	1779	WP_100911829.1	acyltransferase family protein	-

Sequence

Protein

• Length: 304 a.a.
• Molecular weight: 36259.75 Da
• Isoelectric Point: 5.0654

>NTDB_id=200655 CGZ53_RS00360 WP_249630218.1 61558..62472(+) (comR) [Streptococcus uberis strain NZ01]
MKELRKKKQMTREALCGDESELSVRQLARIESGQSNPSLAKALFIAKKLGVPLSDFVNPKELDLPKRYQELKYLILRHPT
YMNTDSIEERESQFDIIFEDYYADLPEEEQVLIDRLQSRFEVYQSGNSVYGQDLLLEYIDQIKKKKTYDLNDIFFIDLYL
TCGYVSSFKETLFDKGIFECFTSKLILLEEKLDFKDLFLLNNVLMTAIAVGLTIEEYVKIRTLLNVCRRIMTITQDFQRM
PIYYMYEWRYTLFHEKDFRKAPYYYQQSLLFARTHGDEYLKTMIVNAWQEDQDKVKTLESQKEI

Nucleotide

• Length: 915 bp

>NTDB_id=200655 CGZ53_RS00360 WP_249630218.1 61558..62472(+) (comR) [Streptococcus uberis strain NZ01]
ATGAAAGAATTGAGAAAGAAAAAACAGATGACACGAGAGGCTCTTTGTGGTGATGAGTCAGAATTATCAGTTCGTCAACT
AGCAAGAATTGAATCTGGACAATCTAATCCTTCTCTAGCCAAAGCTCTTTTTATTGCAAAAAAATTAGGAGTCCCTTTGT
CTGATTTCGTCAATCCTAAAGAACTTGACCTGCCAAAACGCTATCAAGAATTGAAGTATTTGATTTTAAGACATCCGACT
TATATGAATACAGACTCTATAGAAGAAAGAGAATCCCAGTTTGATATCATTTTTGAAGATTATTATGCGGATTTGCCTGA
AGAAGAACAGGTACTCATTGATCGCTTACAGTCTAGATTTGAAGTTTATCAAAGTGGGAATAGCGTTTATGGTCAAGATC
TTTTGCTTGAATATATTGATCAAATAAAAAAGAAAAAAACCTATGATCTGAATGATATCTTTTTTATAGATTTATATTTA
ACCTGTGGTTATGTCTCTTCATTTAAAGAAACACTTTTTGATAAAGGAATCTTTGAATGCTTTACCAGTAAGTTGATCCT
CTTAGAAGAAAAGTTAGATTTCAAAGATTTATTTTTACTCAACAATGTTTTGATGACTGCTATTGCAGTTGGATTAACCA
TTGAAGAATATGTAAAAATACGGACACTATTAAATGTCTGTCGTCGTATTATGACAATTACGCAAGATTTTCAAAGAATG
CCTATTTATTATATGTATGAGTGGCGTTATACCCTATTTCATGAAAAAGATTTCCGAAAAGCTCCCTATTACTATCAACA
GTCCTTGCTATTTGCCCGGACACATGGGGATGAGTATTTAAAAACTATGATAGTAAATGCTTGGCAAGAGGATCAAGATA
AGGTAAAGACATTGGAAAGTCAGAAGGAAATTTAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (1-56)

• ComR tetratricopeptide (ComR_TPR) (65-288)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus pyogenes MGAS315	47.423	95.724	0.454
comR	Streptococcus mutans UA159	42.612	95.724	0.408
comR	Streptococcus pyogenes MGAS8232	42.268	95.724	0.405
comR	Streptococcus infantarius subsp. infantarius ATCC BAA-102	39.59	96.382	0.382
comR	Streptococcus suis P1/7	37.415	96.711	0.362
comR	Streptococcus suis 05ZYH33	37.415	96.711	0.362