Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   CEJ55_RS18610 Genome accession   NZ_CP022393
Coordinates   3662072..3662728 (-) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain E62     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 3657072..3667728
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CEJ55_RS18580 (CEJ55_18590) yecA 3658324..3658989 (-) 666 WP_000847902.1 UPF0149 family protein YecA -
  CEJ55_RS18600 (CEJ55_18610) pgsA 3659638..3660186 (-) 549 WP_001160188.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  CEJ55_RS18605 (CEJ55_18615) uvrC 3660243..3662075 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  CEJ55_RS18610 (CEJ55_18620) letA 3662072..3662728 (-) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  CEJ55_RS26160 - 3662870..3662941 (+) 72 Protein_3429 transcriptional regulator -
  CEJ55_RS25370 yecU 3663024..3663200 (+) 177 WP_000590347.1 protein YecU -
  CEJ55_RS18615 (CEJ55_18625) yecF 3663187..3663411 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  CEJ55_RS18620 (CEJ55_18630) sdiA 3663478..3664200 (-) 723 WP_001154267.1 transcriptional regulator SdiA -
  CEJ55_RS18625 (CEJ55_18635) tcyN 3664430..3665182 (-) 753 WP_001272986.1 L-cystine ABC transporter ATP-binding protein TcyN -
  CEJ55_RS18630 (CEJ55_18640) tcyL 3665179..3665847 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  CEJ55_RS18635 (CEJ55_18645) dcyD 3665862..3666848 (-) 987 WP_001128215.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=200516 CEJ55_RS18610 WP_000611335.1 3662072..3662728(-) (letA) [Escherichia coli strain E62]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=200516 CEJ55_RS18610 WP_000611335.1 3662072..3662728(-) (letA) [Escherichia coli strain E62]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486