Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   SDD27957_08510 Genome accession   CM001076
Coordinates   1628078..1629403 (-) Length   441 a.a.
NCBI ID   EFY03307.1    Uniprot ID   -
Organism   Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1623078..1634403
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SDD27957_08475 - 1623685..1624440 (-) 756 EFY03300.1 hypothetical protein -
  SDD27957_08480 - 1624451..1625146 (-) 696 EFY03301.1 ABC-type multidrug transport system -
  SDD27957_08485 - 1625159..1625347 (-) 189 EFY03302.1 hypothetical protein -
  SDD27957_08490 - 1625352..1625699 (-) 348 EFY03303.1 hypothetical protein -
  SDD27957_08495 - 1626075..1626617 (+) 543 EFY03304.1 transposase IS1239 -
  SDD27957_08500 - 1626813..1627361 (-) 549 EFY03305.1 sigma 54 modulation protein / S30EA ribosomal protein -
  SDD27957_08505 - 1627441..1627821 (-) 381 EFY03306.1 putative late competence protein -
  SDD27957_08510 comFA/cflA 1628078..1629403 (-) 1326 EFY03307.1 putative late competence protein required for DNA uptake Machinery gene
  SDD27957_08515 - 1629459..1630097 (+) 639 EFY03308.1 hypothetical protein -
  SDD27957_08520 - 1630201..1631136 (+) 936 EFY03309.1 Cysteine synthase -
  SDD27957_08525 - 1631287..1631646 (-) 360 EFY03310.1 hypothetical protein -
  SDD27957_08530 - 1631646..1633046 (-) 1401 EFY03311.1 peptidyl-prolyl cis-trans isomerase -
  SDD27957_08535 - 1633083..1633724 (-) 642 EFY03312.1 Two-component response regulator yvqC -

Sequence

Protein


Download         Length: 441 a.a.        Molecular weight: 49359.45 Da        Isoelectric Point: 9.6283

>NTDB_id=20047 SDD27957_08510 EFY03307.1 1628078..1629403(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
MEGIENSYGRLFLKHQLPKEVNHLAKTLESIVIIKGKVTCQRCHYQITAEARLPSGTYYCRFCLVFGRNQADRPLYYIPP
HPFPIANYLQWKGILTPYQESISNQLVKNVHAKKPTLVHAVTGAGKTEMIYGAIAAVVNAGGWVCLASPRVDVCIELANR
LKAAFSCRVTLLHADSEAYQRSPIIVATTHQLLTFYKAFDLLIIDEVDAFPFVNNHQLQYASQQAAKEGASSIVLTATST
KELEEQVKSGELEKLTLARRFHDNPLILPKFIRSFGLLKKIHCQKLPRALVKSISQQRKTGCPLLIFLPIIAMAELVTEL
LKLAFPEEQIACVSSQSADRVKDIDDFRQGKKGILVTTTILERGVTFPGVDVFVLMAQHRGYSSQSLVQIAGRVGRSIER
PTGKVYFFHDGISQAMRNARKEIKEMNQKGYSNDMPPMSTI

Nucleotide


Download         Length: 1326 bp        

>NTDB_id=20047 SDD27957_08510 EFY03307.1 1628078..1629403(-) (comFA/cflA) [Streptococcus dysgalactiae subsp. dysgalactiae ATCC 27957]
ATGGAAGGTATTGAAAACAGTTACGGTCGTTTATTTTTAAAACATCAATTGCCAAAAGAAGTAAATCATCTGGCAAAGAC
CTTGGAAAGTATAGTAATCATAAAAGGTAAAGTCACTTGTCAACGCTGTCATTATCAGATAACCGCAGAAGCGAGATTAC
CAAGCGGCACTTACTACTGTCGCTTCTGTCTCGTTTTTGGCCGAAATCAAGCTGATAGGCCTCTTTATTATATACCTCCA
CATCCTTTTCCTATAGCCAATTATCTTCAATGGAAGGGGATATTAACACCCTACCAAGAAAGTATTTCAAACCAATTAGT
CAAGAATGTTCATGCTAAAAAACCTACTTTAGTGCATGCTGTTACCGGAGCCGGCAAGACAGAGATGATTTATGGTGCCA
TAGCAGCAGTTGTTAATGCTGGAGGTTGGGTTTGTTTAGCTAGCCCAAGGGTCGATGTTTGTATAGAACTTGCTAATCGC
TTAAAAGCTGCTTTTTCTTGCCGAGTTACTCTTTTACACGCTGACTCAGAAGCTTATCAAAGAAGTCCTATTATAGTAGC
TACTACCCATCAATTACTGACCTTTTATAAGGCTTTTGATCTTTTAATCATTGATGAAGTTGATGCTTTTCCTTTTGTCA
ATAATCATCAACTACAATATGCATCGCAGCAAGCCGCTAAAGAAGGCGCTAGTAGTATCGTATTGACCGCGACATCGACC
AAAGAACTGGAAGAGCAGGTCAAAAGTGGGGAATTAGAGAAGTTGACATTAGCTAGACGATTTCATGATAATCCTTTGAT
TCTTCCGAAATTTATCAGGAGTTTTGGCCTATTAAAAAAAATTCACTGTCAAAAACTTCCTCGAGCTCTTGTTAAATCTA
TCAGTCAACAAAGGAAAACAGGATGTCCACTGCTAATTTTTCTTCCTATTATTGCCATGGCAGAATTAGTTACTGAATTA
TTAAAGTTAGCTTTTCCAGAGGAGCAAATTGCCTGTGTCTCTAGCCAATCAGCTGACAGAGTTAAAGACATTGATGACTT
TCGTCAAGGAAAGAAAGGCATTTTGGTGACCACCACAATATTGGAAAGGGGTGTTACTTTCCCAGGTGTGGATGTCTTTG
TGCTTATGGCACAGCATCGAGGATACAGTTCTCAAAGCTTGGTTCAAATCGCAGGTCGTGTCGGGAGATCTATCGAAAGG
CCAACAGGAAAGGTGTATTTCTTTCACGATGGGATTAGCCAAGCAATGCGCAATGCAAGAAAAGAAATTAAAGAAATGAA
TCAGAAAGGTTATTCGAATGATATGCCTCCTATGTCAACAATTTAG

Domains

Predicted by InterproScan.

DEAD/DEAH box helicase (DEAD)

(99-244)

Helicase conserved C-terminal domain (Helicase_C)

(289-396)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae D39

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae R6

53.081

95.692

0.508
  comFA/cflA Streptococcus pneumoniae TIGR4

53.081

95.692

0.508
  comFA/cflA Streptococcus mitis NCTC 12261

51.628

97.506

0.503
  comFA/cflA Streptococcus mitis SK321

51.765

96.372

0.499
  comFA Lactococcus lactis subsp. cremoris KW2

45.366

92.971

0.422
  comFA Latilactobacillus sakei subsp. sakei 23K

37.355

97.732

0.365

Multiple sequence alignment