Detailed information    

insolico Bioinformatically predicted

Overview

Name   eeP   Type   Regulator
Locus tag   A4W85_RS06470 Genome accession   NZ_CP017570
Coordinates   1272424..1273701 (-) Length   425 a.a.
NCBI ID   WP_076632067.1    Uniprot ID   A0AAX0VCT6
Organism   Latilactobacillus sakei strain TMW 1.578     
Function   processing of ComS (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1254814..1303729 1272424..1273701 within 0


Gene organization within MGE regions


Location: 1254814..1303729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A4W85_RS06430 (A4W85_06385) - 1254814..1255785 (-) 972 WP_099947680.1 restriction endonuclease -
  A4W85_RS10030 - 1255962..1256342 (+) 381 WP_082268150.1 restriction endonuclease subunit S -
  A4W85_RS06440 (A4W85_06400) - 1257870..1259723 (-) 1854 WP_056947053.1 DEAD/DEAH box helicase -
  A4W85_RS06445 (A4W85_06405) - 1259713..1260984 (-) 1272 WP_141265858.1 hypothetical protein -
  A4W85_RS06450 (A4W85_06410) - 1260981..1263905 (-) 2925 WP_112212616.1 type III restriction-modification system endonuclease -
  A4W85_RS06455 (A4W85_06415) - 1263917..1265977 (-) 2061 WP_251944663.1 site-specific DNA-methyltransferase -
  A4W85_RS06460 (A4W85_06420) - 1266174..1270514 (-) 4341 WP_251944665.1 PolC-type DNA polymerase III -
  A4W85_RS06465 (A4W85_06425) - 1270689..1272398 (-) 1710 WP_011374954.1 proline--tRNA ligase -
  A4W85_RS06470 (A4W85_06430) eeP 1272424..1273701 (-) 1278 WP_076632067.1 RIP metalloprotease RseP Regulator
  A4W85_RS06475 (A4W85_06435) - 1273908..1274696 (-) 789 WP_011374956.1 phosphatidate cytidylyltransferase -
  A4W85_RS06480 (A4W85_06440) - 1274727..1275482 (-) 756 WP_011374957.1 isoprenyl transferase -
  A4W85_RS06485 (A4W85_06445) - 1275650..1278397 (+) 2748 WP_056947073.1 YhgE/Pip domain-containing protein -
  A4W85_RS06490 (A4W85_06450) frr 1278455..1279012 (-) 558 WP_011374959.1 ribosome recycling factor -
  A4W85_RS06495 (A4W85_06455) pyrH 1279015..1279740 (-) 726 WP_099947391.1 UMP kinase -
  A4W85_RS06500 (A4W85_06460) tsf 1279876..1280751 (-) 876 WP_011374961.1 translation elongation factor Ts -
  A4W85_RS06505 (A4W85_06465) rpsB 1280858..1281652 (-) 795 WP_011374962.1 30S ribosomal protein S2 -
  A4W85_RS06510 (A4W85_06470) - 1281820..1282095 (-) 276 WP_076648185.1 GIY-YIG nuclease family protein -
  A4W85_RS06515 (A4W85_06475) - 1282088..1282831 (-) 744 WP_011374964.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  A4W85_RS06520 (A4W85_06480) - 1282953..1283576 (+) 624 WP_251944670.1 lysophospholipid acyltransferase family protein -
  A4W85_RS06525 (A4W85_06485) - 1283638..1284573 (-) 936 WP_096584678.1 alpha/beta hydrolase -
  A4W85_RS06530 (A4W85_06490) - 1284714..1286504 (-) 1791 WP_096584675.1 ABC transporter ATP-binding protein -
  A4W85_RS06535 (A4W85_06495) - 1286509..1288251 (-) 1743 Protein_1258 ABC transporter ATP-binding protein -
  A4W85_RS06540 (A4W85_06500) - 1288393..1288623 (-) 231 WP_011374970.1 YneF family protein -
  A4W85_RS06545 (A4W85_06505) - 1288704..1288946 (-) 243 WP_016265356.1 DUF896 domain-containing protein -
  A4W85_RS06550 (A4W85_06510) lexA 1289081..1289695 (+) 615 WP_011374972.1 transcriptional repressor LexA -
  A4W85_RS06555 (A4W85_06515) - 1289829..1290347 (-) 519 WP_011374973.1 adenine phosphoribosyltransferase -
  A4W85_RS06560 (A4W85_06520) recJ 1290371..1292683 (-) 2313 WP_025016402.1 single-stranded-DNA-specific exonuclease RecJ -
  A4W85_RS06565 (A4W85_06525) galE 1292828..1293819 (+) 992 Protein_1264 UDP-glucose 4-epimerase GalE -
  A4W85_RS06570 (A4W85_06530) - 1293905..1294270 (+) 366 WP_112217745.1 DUF1304 domain-containing protein -
  A4W85_RS06575 (A4W85_06535) - 1294287..1294613 (+) 327 WP_016265359.1 heavy metal-binding domain-containing protein -
  A4W85_RS06580 (A4W85_06540) - 1294663..1296498 (-) 1836 WP_251944672.1 WxL domain-containing protein -
  A4W85_RS06585 (A4W85_06545) - 1296488..1296883 (-) 396 WP_016265361.1 LPXTG cell wall anchor domain-containing protein -
  A4W85_RS06590 (A4W85_06550) - 1296873..1297916 (-) 1044 WP_056947110.1 DUF916 and DUF3324 domain-containing protein -
  A4W85_RS06595 (A4W85_06555) - 1298037..1298648 (-) 612 WP_011374982.1 WxL domain-containing protein -
  A4W85_RS06600 (A4W85_06560) - 1298795..1299304 (-) 510 WP_011374983.1 DinB family protein -
  A4W85_RS06605 (A4W85_06565) - 1299451..1299645 (+) 195 WP_011374984.1 hypothetical protein -
  A4W85_RS06610 (A4W85_06570) lepA 1299685..1301523 (-) 1839 WP_011374985.1 translation elongation factor 4 -
  A4W85_RS06615 - 1301658..1301801 (-) 144 WP_011374986.1 hypothetical protein -
  A4W85_RS06620 (A4W85_06575) - 1301945..1302256 (+) 312 WP_056947116.1 hypothetical protein -
  A4W85_RS06625 (A4W85_06580) - 1302361..1302891 (+) 531 WP_016265368.1 hypothetical protein -
  A4W85_RS06630 (A4W85_06585) - 1302893..1303729 (+) 837 WP_251944674.1 DNA/RNA non-specific endonuclease -

Sequence

Protein


Download         Length: 425 a.a.        Molecular weight: 46636.29 Da        Isoelectric Point: 9.5179

>NTDB_id=200457 A4W85_RS06470 WP_076632067.1 1272424..1273701(-) (eeP) [Latilactobacillus sakei strain TMW 1.578]
MAAIIAFIIIFGILVVVHEFGHFYMAKRSGILVREFSVGMGPKLFATRKNGTTYTIRWLPLGGYVRMAGMADDESEIEAG
TQATLILDEQGRVQQINTSDKVTTLNGVPFQIAKTDLQKELWVEGYEGGDESEMKRYPVLHDATIIEADGTEVQIAPVDV
QFQSATLINRMLTNFAGPFNNFILAILAFILFAFLSGGVPQQSNQIGTVQENSAAQKAGLKANDRLLKVDNKKVASFTDF
SAIISEHPNETVAVRVQRGATEKTIKVTPKAVKVANQKEKVGQVGVTQKVKMDHSLKAKISYGFTQAWSIASQIFKILGS
FLTGGFSLDKLSGPVGMYSMTTQFTQQGFNALVYFLAFLSLNLGIMNLIPIPALDGGKLVLNIIEAIRRKPISPEKEGIV
TLIGVGIMVLLMVLVTWNDIQRFFF

Nucleotide


Download         Length: 1278 bp        

>NTDB_id=200457 A4W85_RS06470 WP_076632067.1 1272424..1273701(-) (eeP) [Latilactobacillus sakei strain TMW 1.578]
TTGGCTGCAATTATTGCGTTTATCATCATCTTTGGTATTTTAGTAGTCGTTCATGAATTTGGGCATTTTTACATGGCTAA
GCGCTCAGGCATTTTGGTGCGTGAGTTTTCTGTCGGCATGGGGCCTAAATTATTTGCAACTCGCAAAAACGGCACAACTT
ACACCATCCGGTGGTTACCATTAGGTGGTTACGTTCGAATGGCGGGAATGGCCGACGATGAATCTGAAATTGAAGCGGGC
ACACAAGCGACTTTAATTTTGGACGAACAAGGACGCGTTCAACAGATTAATACAAGTGACAAGGTCACCACGTTAAACGG
GGTGCCTTTCCAAATTGCTAAAACAGATTTACAAAAGGAATTGTGGGTCGAAGGTTACGAAGGCGGCGACGAGTCAGAAA
TGAAACGTTATCCCGTCTTACATGATGCGACGATTATCGAAGCAGATGGAACGGAAGTGCAAATCGCACCCGTGGATGTC
CAATTCCAATCAGCAACGTTGATTAATCGGATGTTAACGAACTTTGCCGGACCATTTAATAACTTCATCCTCGCAATTCT
AGCCTTTATCCTCTTCGCTTTTCTAAGCGGGGGTGTGCCACAGCAATCCAATCAAATTGGCACGGTACAAGAGAATTCAG
CTGCTCAAAAGGCAGGCTTAAAAGCCAACGATCGTCTTTTGAAGGTTGATAACAAAAAAGTAGCGAGCTTCACTGACTTT
AGTGCGATAATTTCAGAACACCCTAACGAAACTGTTGCGGTGCGCGTTCAACGGGGCGCAACTGAAAAGACAATTAAGGT
GACTCCCAAGGCTGTCAAAGTGGCTAACCAAAAAGAAAAGGTTGGTCAAGTAGGGGTCACACAAAAAGTCAAAATGGATC
ATAGCCTAAAGGCCAAGATTTCTTACGGCTTTACACAAGCTTGGTCAATTGCCAGTCAGATTTTCAAGATCCTCGGGTCA
TTTTTAACCGGTGGATTCTCACTAGATAAATTATCGGGGCCGGTCGGCATGTATTCAATGACGACCCAATTTACCCAACA
AGGCTTTAATGCGTTAGTTTATTTCTTAGCGTTCTTATCACTTAATTTGGGGATTATGAATCTAATTCCGATTCCGGCGT
TAGATGGTGGTAAGTTAGTCTTGAACATTATTGAAGCGATTCGTCGCAAACCAATTTCACCTGAAAAAGAAGGCATCGTG
ACATTAATCGGTGTCGGTATTATGGTGTTATTAATGGTCTTAGTCACGTGGAACGATATACAACGATTTTTCTTTTAG

Domains

Predicted by InterproScan.

PDZ domain (PDZ_6)

(206-258)

Peptidase family M50 (Peptidase_M50)

(6-411)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  eeP Streptococcus thermophilus LMD-9

48.148

100

0.489
  eeP Streptococcus thermophilus LMG 18311

48.148

100

0.489

Multiple sequence alignment