Detailed information NTG0198568

Bioinformatically predicted

Overview

• Name: comK/comK1
• Type: Regulator
• Locus tag: BJG89_RS09990
• Genome accession: NZ_CP017466
• Coordinates: 2105111..2105674 (-)
• Length: 187 a.a.
• NCBI ID: WP_096810450.1
• Uniprot ID: A0A291JM98
• Organism: Staphylococcus nepalensis strain JS11
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2091529..2104607	2105111..2105674	flank	504

Gene organization within MGE regions

Location: 2091529..2105674

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJG89_RS09915 (BJG89_09765)	-	2091529..2091951 (-)	423	WP_096810439.1	MarR family transcriptional regulator	-
BJG89_RS09920 (BJG89_09770)	-	2092154..2093158 (+)	1005	WP_096810440.1	acyltransferase family protein	-
BJG89_RS09925 (BJG89_09775)	-	2093279..2094436 (+)	1158	WP_096810441.1	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	-
BJG89_RS09935 (BJG89_09780)	menB	2095277..2096095 (-)	819	WP_096810442.1	1,4-dihydroxy-2-naphthoyl-CoA synthase	-
BJG89_RS09940 (BJG89_09785)	menH	2096088..2096894 (-)	807	WP_096810443.1	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	-
BJG89_RS09945 (BJG89_09790)	menD	2096881..2098563 (-)	1683	WP_096810444.1	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	-
BJG89_RS09950 (BJG89_09795)	-	2098556..2099908 (-)	1353	WP_096810445.1	isochorismate synthase	-
BJG89_RS09955 (BJG89_09800)	-	2100093..2101031 (+)	939	WP_096810446.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
BJG89_RS09960 (BJG89_09805)	-	2101112..2101669 (-)	558	WP_096810447.1	GNAT family N-acetyltransferase	-
BJG89_RS09965 (BJG89_09810)	-	2101845..2102057 (+)	213	WP_046208085.1	TM2 domain-containing protein	-
BJG89_RS14900	-	2102168..2102257 (+)	90	WP_249776154.1	SAR1012 family small protein	-
BJG89_RS09970 (BJG89_09815)	-	2102821..2103492 (+)	672	WP_096810448.1	DUF4352 domain-containing protein	-
BJG89_RS09975 (BJG89_09820)	-	2103513..2104607 (+)	1095	WP_096810449.1	tyrosine-type recombinase/integrase	-
BJG89_RS09990 (BJG89_09835)	comK/comK1	2105111..2105674 (-)	564	WP_096810450.1	competence protein ComK	Regulator

Sequence

Protein

• Length: 187 a.a.
• Molecular weight: 22040.29 Da
• Isoelectric Point: 9.4398

>NTDB_id=198568 BJG89_RS09990 WP_096810450.1 2105111..2105674(-) (comK/comK1) [Staphylococcus nepalensis strain JS11]
MNQPYIIKKGDMALQPCHLAIGQYEGTRVLRYKEDEDVIKERTHKIIDRSCRFYGSSYVFKKEDTIRITGISSKPPILFT
PLFPTYFFPTHSDRKTQNTWINIHYVQSIRSLKDKKCRVNFVDNQSIIVSISAHSMHHQYLNGIYYYYMMDRAARVATFD
PESPIDYTKPQLNIYEALAKYSLFESK

Nucleotide

• Length: 564 bp

>NTDB_id=198568 BJG89_RS09990 WP_096810450.1 2105111..2105674(-) (comK/comK1) [Staphylococcus nepalensis strain JS11]
ATGAATCAACCGTACATTATTAAAAAAGGTGATATGGCATTACAACCTTGCCATCTAGCTATTGGACAATATGAAGGAAC
GCGCGTACTAAGGTATAAAGAAGATGAAGATGTGATTAAAGAACGTACACATAAAATTATTGATCGTTCCTGTAGATTTT
ATGGTAGTAGTTATGTGTTTAAGAAAGAAGACACCATTCGGATCACTGGTATTAGCAGTAAACCCCCAATTCTATTTACT
CCATTATTTCCCACTTATTTTTTTCCAACTCATTCTGATAGAAAAACACAAAATACATGGATTAACATCCATTATGTTCA
AAGTATTAGATCATTAAAAGATAAAAAATGTAGAGTTAACTTTGTTGATAATCAGTCTATCATTGTCAGTATTTCAGCAC
ATAGCATGCATCATCAATATTTAAATGGTATTTATTATTATTATATGATGGACAGAGCAGCTAGGGTTGCAACTTTTGAT
CCGGAATCTCCAATAGATTATACGAAACCACAACTTAATATATACGAAGCATTAGCTAAATACTCTTTGTTTGAAAGCAA
ATAG

Domains

Predicted by InterproScan.

• ComK protein (ComK) (4-152)

3D structure

• AlphaFold DB: A0A291JM98

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comK/comK1	Staphylococcus aureus MW2	53.552	97.861	0.524
comK/comK1	Staphylococcus aureus N315	53.552	97.861	0.524