Detailed information
Bioinformatically predicted
Overview
| Name | ccrA | Type | Machinery gene |
| Locus tag | BJG89_RS00305 | Genome accession | NZ_CP017466 |
| Coordinates | 70337..71686 (-) | Length | 449 a.a. |
| NCBI ID | WP_096807993.1 | Uniprot ID | - |
| Organism | Staphylococcus nepalensis strain JS11 | ||
| Function | promote SCCmec transfer (predicted from homology) Homologous recombination |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| SCCmec | 41533..127093 | 70337..71686 | within | 0 |
Gene organization within MGE regions
Location: 41533..127093
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| BJG89_RS00170 (BJG89_00170) | ccrC | 41533..43215 (+) | 1683 | WP_096807968.1 | cassette chromosome recombinase CcrC | - |
| BJG89_RS00175 (BJG89_00175) | - | 43314..43652 (+) | 339 | WP_096807969.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| BJG89_RS00180 (BJG89_00180) | - | 43748..44059 (+) | 312 | WP_096807970.1 | DUF960 family protein | - |
| BJG89_RS00185 (BJG89_00185) | - | 44075..44578 (+) | 504 | WP_096807971.1 | DUF1643 domain-containing protein | - |
| BJG89_RS00190 (BJG89_00190) | - | 45093..45761 (+) | 669 | WP_096807972.1 | Wzz/FepE/Etk N-terminal domain-containing protein | - |
| BJG89_RS00195 (BJG89_00195) | - | 45776..46465 (+) | 690 | WP_096807973.1 | polysaccharide biosynthesis tyrosine autokinase | - |
| BJG89_RS00200 (BJG89_00200) | - | 46462..47226 (+) | 765 | WP_096807974.1 | tyrosine-protein phosphatase | - |
| BJG89_RS00205 (BJG89_00205) | - | 47250..49061 (+) | 1812 | WP_096807975.1 | polysaccharide biosynthesis protein | - |
| BJG89_RS00210 (BJG89_00210) | - | 49063..50445 (+) | 1383 | WP_096807976.1 | oligosaccharide repeat unit polymerase | - |
| BJG89_RS00215 (BJG89_00215) | wzx | 50442..51806 (+) | 1365 | WP_096807977.1 | O-unit flippase-like protein | - |
| BJG89_RS00220 (BJG89_00220) | - | 51823..53010 (+) | 1188 | WP_096807978.1 | glycosyltransferase | - |
| BJG89_RS00225 (BJG89_00225) | - | 53012..53878 (+) | 867 | WP_096807979.1 | glycosyltransferase family 2 protein | - |
| BJG89_RS00230 (BJG89_00230) | - | 53875..54432 (+) | 558 | WP_096807980.1 | acyltransferase | - |
| BJG89_RS00235 (BJG89_00235) | - | 54434..55435 (+) | 1002 | WP_096807981.1 | NAD-dependent epimerase | - |
| BJG89_RS00240 (BJG89_00240) | - | 55458..56732 (+) | 1275 | WP_096807982.1 | nucleotide sugar dehydrogenase | - |
| BJG89_RS00245 (BJG89_00245) | - | 56734..57879 (+) | 1146 | WP_096807983.1 | glycosyltransferase family 4 protein | - |
| BJG89_RS00250 (BJG89_00250) | - | 57889..58446 (+) | 558 | WP_096807984.1 | sugar transferase | - |
| BJG89_RS00255 (BJG89_00255) | - | 58446..59306 (+) | 861 | WP_096807985.1 | NAD-dependent epimerase/dehydratase family protein | - |
| BJG89_RS00260 (BJG89_00260) | - | 60034..63063 (-) | 3030 | WP_096807986.1 | type I restriction endonuclease subunit R | - |
| BJG89_RS00265 (BJG89_00265) | - | 63076..64386 (-) | 1311 | WP_096807987.1 | restriction endonuclease subunit S | - |
| BJG89_RS00270 (BJG89_00270) | - | 64376..66163 (-) | 1788 | WP_096807988.1 | type I restriction-modification system subunit M | - |
| BJG89_RS00275 (BJG89_00275) | - | 66306..66527 (-) | 222 | WP_037576854.1 | hypothetical protein | - |
| BJG89_RS00280 (BJG89_00280) | - | 66542..67045 (-) | 504 | WP_096807989.1 | DUF1643 domain-containing protein | - |
| BJG89_RS00285 (BJG89_00285) | - | 67060..67371 (-) | 312 | WP_096807990.1 | DUF960 family protein | - |
| BJG89_RS00290 (BJG89_00290) | - | 67467..67805 (-) | 339 | WP_096807991.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| BJG89_RS00295 (BJG89_00295) | - | 68362..68649 (+) | 288 | WP_232514191.1 | hypothetical protein | - |
| BJG89_RS00300 (BJG89_00300) | ccrB | 68684..70315 (-) | 1632 | WP_096807992.1 | cassette chromosome recombinase CcrB | Machinery gene |
| BJG89_RS00305 (BJG89_00305) | ccrA | 70337..71686 (-) | 1350 | WP_096807993.1 | cassette chromosome recombinase CcrA | Machinery gene |
| BJG89_RS00310 (BJG89_00310) | - | 71878..72153 (-) | 276 | WP_096807994.1 | hypothetical protein | - |
| BJG89_RS00315 (BJG89_00315) | cch1 | 72222..74009 (-) | 1788 | WP_096807995.1 | cassette chromosome replicative helicase | - |
| BJG89_RS00320 (BJG89_00320) | ssb | 74009..74254 (-) | 246 | WP_096807996.1 | cassette chromosome ssDNA-binding protein | - |
| BJG89_RS00325 (BJG89_00325) | - | 74392..75435 (+) | 1044 | WP_096807997.1 | ACP synthase | - |
| BJG89_RS00330 (BJG89_00330) | - | 75790..77172 (+) | 1383 | WP_096807998.1 | YfcC family protein | - |
| BJG89_RS00335 (BJG89_00335) | - | 77205..78092 (+) | 888 | WP_096807999.1 | succinylglutamate desuccinylase/aspartoacylase family protein | - |
| BJG89_RS00340 (BJG89_00340) | - | 78103..78924 (+) | 822 | WP_096808000.1 | MurR/RpiR family transcriptional regulator | - |
| BJG89_RS00345 (BJG89_00345) | - | 78936..80063 (+) | 1128 | WP_096808001.1 | M20 family metallopeptidase | - |
| BJG89_RS00355 (BJG89_00350) | - | 80508..81062 (+) | 555 | WP_096808002.1 | DUF488 family protein | - |
| BJG89_RS14540 | - | 81194..81367 (-) | 174 | WP_096808003.1 | hypothetical protein | - |
| BJG89_RS00365 (BJG89_00355) | - | 81383..82528 (-) | 1146 | WP_096808004.1 | globin domain-containing protein | - |
| BJG89_RS00370 (BJG89_00360) | - | 82745..83164 (+) | 420 | WP_096808005.1 | hemerythrin domain-containing protein | - |
| BJG89_RS00375 (BJG89_00365) | - | 83166..83468 (+) | 303 | WP_096808006.1 | hypothetical protein | - |
| BJG89_RS00380 (BJG89_00370) | - | 83486..83758 (+) | 273 | WP_096808007.1 | hypothetical protein | - |
| BJG89_RS00385 (BJG89_00375) | - | 83758..87438 (+) | 3681 | WP_096808008.1 | nitrate reductase subunit alpha | - |
| BJG89_RS00390 (BJG89_00380) | narH | 87428..88945 (+) | 1518 | WP_096808009.1 | nitrate reductase subunit beta | - |
| BJG89_RS00395 (BJG89_00385) | narJ | 88942..89541 (+) | 600 | WP_096808010.1 | nitrate reductase molybdenum cofactor assembly chaperone | - |
| BJG89_RS00400 (BJG89_00390) | narI | 89584..90285 (+) | 702 | WP_096808011.1 | respiratory nitrate reductase subunit gamma | - |
| BJG89_RS00405 (BJG89_00395) | - | 90438..91592 (+) | 1155 | WP_096808012.1 | nitrate/nitrite transporter | - |
| BJG89_RS00410 (BJG89_00400) | - | 91888..93747 (+) | 1860 | WP_096808013.1 | AbiA family abortive infection protein | - |
| BJG89_RS00415 (BJG89_00405) | - | 93781..95106 (+) | 1326 | WP_096808014.1 | DUF6038 family protein | - |
| BJG89_RS00420 (BJG89_00410) | - | 95317..96417 (+) | 1101 | WP_096808015.1 | DNA polymerase | - |
| BJG89_RS00425 (BJG89_00415) | - | 96410..96778 (+) | 369 | WP_096808016.1 | hypothetical protein | - |
| BJG89_RS00430 (BJG89_00420) | - | 96778..98421 (+) | 1644 | WP_096808017.1 | DUF5906 domain-containing protein | - |
| BJG89_RS00435 (BJG89_00425) | ccrC | 98646..100322 (+) | 1677 | WP_096808018.1 | cassette chromosome recombinase CcrC | - |
| BJG89_RS00440 (BJG89_00430) | - | 100428..100766 (+) | 339 | WP_096808019.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| BJG89_RS00445 (BJG89_00435) | - | 100862..101173 (+) | 312 | WP_096808020.1 | DUF960 family protein | - |
| BJG89_RS00450 (BJG89_00440) | - | 101188..101691 (+) | 504 | WP_096808021.1 | DUF1643 domain-containing protein | - |
| BJG89_RS00455 (BJG89_00445) | - | 101705..101926 (+) | 222 | WP_096808022.1 | hypothetical protein | - |
| BJG89_RS00460 (BJG89_00450) | - | 102037..103206 (-) | 1170 | WP_096808023.1 | restriction endonuclease subunit S | - |
| BJG89_RS00465 (BJG89_00455) | - | 103199..104755 (-) | 1557 | WP_096808024.1 | type I restriction-modification system subunit M | - |
| BJG89_RS00470 (BJG89_00460) | - | 104873..107665 (-) | 2793 | WP_096808025.1 | type I restriction endonuclease subunit R | - |
| BJG89_RS00475 (BJG89_00465) | - | 107893..108972 (+) | 1080 | WP_096808026.1 | hypothetical protein | - |
| BJG89_RS00480 (BJG89_00470) | - | 109007..109756 (+) | 750 | WP_096808027.1 | hypothetical protein | - |
| BJG89_RS00485 (BJG89_00475) | - | 109798..110774 (+) | 977 | Protein_93 | DUF1002 domain-containing protein | - |
| BJG89_RS00490 | - | 111055..111248 (+) | 194 | Protein_94 | sugar phosphate nucleotidyltransferase | - |
| BJG89_RS00495 (BJG89_00480) | - | 111611..114484 (+) | 2874 | WP_096808028.1 | bifunctional glycosyltransferase/CDP-glycerol:glycerophosphate glycerophosphotransferase | - |
| BJG89_RS00500 (BJG89_00485) | tnpA | 114663..115139 (-) | 477 | WP_096808029.1 | IS200/IS605 family transposase | - |
| BJG89_RS00505 (BJG89_00490) | - | 115680..116297 (+) | 618 | WP_038024172.1 | CadD family cadmium resistance transporter | - |
| BJG89_RS00510 (BJG89_00495) | - | 116316..116657 (+) | 342 | WP_002469817.1 | ArsR/SmtB family transcription factor | - |
| BJG89_RS00515 (BJG89_00500) | arsC | 116677..117078 (-) | 402 | WP_002434455.1 | arsenate reductase (thioredoxin) | - |
| BJG89_RS00520 (BJG89_00505) | arsB | 117096..118388 (-) | 1293 | WP_186333490.1 | arsenite efflux transporter membrane subunit ArsB | - |
| BJG89_RS00525 (BJG89_00510) | arsR | 118385..118699 (-) | 315 | WP_065865872.1 | As(III)-sensing metalloregulatory transcriptional repressor ArsR | - |
| BJG89_RS00530 (BJG89_00515) | - | 118904..119104 (+) | 201 | WP_038025466.1 | hypothetical protein | - |
| BJG89_RS00535 (BJG89_00520) | - | 119137..119457 (+) | 321 | WP_070704789.1 | ArsR/SmtB family transcription factor | - |
| BJG89_RS00540 (BJG89_00525) | - | 119547..120431 (+) | 885 | WP_096808031.1 | permease | - |
| BJG89_RS00545 | - | 120445..120582 (+) | 138 | WP_096808032.1 | hypothetical protein | - |
| BJG89_RS00550 (BJG89_00530) | - | 120717..120896 (-) | 180 | WP_065865875.1 | hypothetical protein | - |
| BJG89_RS14665 | - | 120953..121165 (-) | 213 | WP_232514192.1 | hypothetical protein | - |
| BJG89_RS00555 (BJG89_00535) | - | 121190..121729 (-) | 540 | WP_232514193.1 | HTH domain-containing protein | - |
| BJG89_RS00560 (BJG89_00540) | - | 121913..122329 (-) | 417 | WP_232514194.1 | JAB domain-containing protein | - |
| BJG89_RS00565 (BJG89_00545) | - | 122350..122856 (-) | 507 | WP_096808033.1 | DUF1643 domain-containing protein | - |
| BJG89_RS00570 (BJG89_00550) | - | 122872..123183 (-) | 312 | WP_096808034.1 | DUF960 family protein | - |
| BJG89_RS00575 (BJG89_00555) | - | 123279..123617 (-) | 339 | WP_096808035.1 | SAUGI family uracil-DNA glycosylase inhibitor | - |
| BJG89_RS00580 (BJG89_00560) | ccrB | 124092..125723 (-) | 1632 | WP_096808036.1 | cassette chromosome recombinase CcrB | Machinery gene |
| BJG89_RS00585 (BJG89_00565) | ccrA | 125744..127093 (-) | 1350 | WP_096808037.1 | cassette chromosome recombinase CcrA | Machinery gene |
Sequence
Protein
Download Length: 449 a.a. Molecular weight: 52605.47 Da Isoelectric Point: 10.1743
>NTDB_id=198543 BJG89_RS00305 WP_096807993.1 70337..71686(-) (ccrA) [Staphylococcus nepalensis strain JS11]
MKQAMGYLRQSTTKQQSLPAQKQAIKTLAEKHNIRHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVNNGIKEKARQGKLITTHAPFGYHYK
RDTFTINKNESPTVIAVFNYYLQGNGYKKITQFLEEDNKLLNRKPYQVRNIIMNPNYCGRVINKYGQYDNIFPSIVSTNM
YEQAQALRSQKQIKRTPSDNQLKQKIKCPYCGSKLTNMTIRKGTHSLRYYVCPRNMNESRFVCDFKGINAQELETSVLTT
CQDFFQNQQLYSKINQSIQKQLKNQRDIETKNTLNHEQLIEKLAKGKIDAETFREQTQLLRQQSKPISSINAFQIKRTFQ
NVIKQRFTLNMLYPYIDEIHITKKKILVGIYFKNEPLNIINQTTQSSIA
MKQAMGYLRQSTTKQQSLPAQKQAIKTLAEKHNIRHITFYSDKQSGRTDKRNGYQQITELIQQGQCDVLCCYRLNRLHRN
LKNALKLMKLCQKYHVHILSVHDGYFDMDKAFDRLKLNIFISLAELESDNIGEQVNNGIKEKARQGKLITTHAPFGYHYK
RDTFTINKNESPTVIAVFNYYLQGNGYKKITQFLEEDNKLLNRKPYQVRNIIMNPNYCGRVINKYGQYDNIFPSIVSTNM
YEQAQALRSQKQIKRTPSDNQLKQKIKCPYCGSKLTNMTIRKGTHSLRYYVCPRNMNESRFVCDFKGINAQELETSVLTT
CQDFFQNQQLYSKINQSIQKQLKNQRDIETKNTLNHEQLIEKLAKGKIDAETFREQTQLLRQQSKPISSINAFQIKRTFQ
NVIKQRFTLNMLYPYIDEIHITKKKILVGIYFKNEPLNIINQTTQSSIA
Nucleotide
Download Length: 1350 bp
>NTDB_id=198543 BJG89_RS00305 WP_096807993.1 70337..71686(-) (ccrA) [Staphylococcus nepalensis strain JS11]
ATGAAACAAGCAATGGGTTACTTACGTCAAAGTACAACAAAACAACAATCACTTCCGGCACAGAAACAAGCCATCAAGAC
ATTAGCTGAAAAACACAATATTCGACACATCACATTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAACAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTGTGTCAAAAATACCATGTCCATATCTTAAGCGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAATTAGAATCTGATAATATTGGCGAAC
AAGTAAACAACGGGATAAAAGAAAAAGCGCGTCAGGGTAAATTGATAACTACACACGCCCCCTTTGGTTACCACTACAAA
CGTGATACATTCACGATAAATAAGAATGAATCACCAACGGTAATTGCCGTATTCAATTACTATCTTCAAGGTAATGGCTA
TAAAAAAATTACACAGTTCTTAGAAGAAGATAACAAACTACTCAACCGGAAACCTTATCAAGTACGTAATATTATTATGA
ATCCCAATTACTGTGGTCGTGTTATCAATAAATATGGACAATATGACAACATATTTCCGTCTATTGTTTCTACAAATATG
TACGAACAAGCGCAAGCTCTACGATCGCAAAAACAAATCAAACGAACACCTTCAGACAATCAACTCAAACAAAAAATCAA
ATGCCCCTACTGTGGATCTAAACTTACCAATATGACCATTAGAAAAGGGACGCATTCATTACGTTACTATGTCTGCCCAA
GAAATATGAATGAATCACGTTTTGTTTGTGACTTCAAAGGCATCAATGCACAAGAATTAGAAACAAGTGTTTTAACGACT
TGTCAGGACTTCTTTCAGAACCAACAGCTATACTCAAAAATCAACCAATCAATTCAAAAACAACTCAAAAACCAAAGAGA
CATAGAAACCAAAAATACACTAAACCATGAACAGCTGATAGAAAAATTAGCCAAAGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATTATTACGTCAACAATCTAAACCTATATCGTCAATCAATGCATTTCAAATTAAAAGGACTTTTCAA
AACGTCATTAAACAACGTTTCACGTTAAACATGTTATACCCTTATATTGATGAAATTCATATCACAAAAAAGAAAATACT
TGTTGGCATTTATTTCAAAAATGAACCTTTAAACATAATCAATCAAACTACGCAATCATCGATTGCTTAA
ATGAAACAAGCAATGGGTTACTTACGTCAAAGTACAACAAAACAACAATCACTTCCGGCACAGAAACAAGCCATCAAGAC
ATTAGCTGAAAAACACAATATTCGACACATCACATTTTATAGCGATAAGCAATCAGGACGCACTGATAAGCGAAACGGTT
ACCAACAAATTACTGAACTGATTCAACAAGGACAATGTGACGTACTATGTTGCTATCGTCTGAATCGACTTCATCGTAAT
CTAAAAAATGCATTAAAACTCATGAAATTGTGTCAAAAATACCATGTCCATATCTTAAGCGTTCATGATGGCTATTTTGA
TATGGATAAAGCATTCGATCGGCTCAAACTCAATATTTTCATCAGCTTGGCCGAATTAGAATCTGATAATATTGGCGAAC
AAGTAAACAACGGGATAAAAGAAAAAGCGCGTCAGGGTAAATTGATAACTACACACGCCCCCTTTGGTTACCACTACAAA
CGTGATACATTCACGATAAATAAGAATGAATCACCAACGGTAATTGCCGTATTCAATTACTATCTTCAAGGTAATGGCTA
TAAAAAAATTACACAGTTCTTAGAAGAAGATAACAAACTACTCAACCGGAAACCTTATCAAGTACGTAATATTATTATGA
ATCCCAATTACTGTGGTCGTGTTATCAATAAATATGGACAATATGACAACATATTTCCGTCTATTGTTTCTACAAATATG
TACGAACAAGCGCAAGCTCTACGATCGCAAAAACAAATCAAACGAACACCTTCAGACAATCAACTCAAACAAAAAATCAA
ATGCCCCTACTGTGGATCTAAACTTACCAATATGACCATTAGAAAAGGGACGCATTCATTACGTTACTATGTCTGCCCAA
GAAATATGAATGAATCACGTTTTGTTTGTGACTTCAAAGGCATCAATGCACAAGAATTAGAAACAAGTGTTTTAACGACT
TGTCAGGACTTCTTTCAGAACCAACAGCTATACTCAAAAATCAACCAATCAATTCAAAAACAACTCAAAAACCAAAGAGA
CATAGAAACCAAAAATACACTAAACCATGAACAGCTGATAGAAAAATTAGCCAAAGGCAAAATTGATGCAGAAACGTTCA
GAGAACAAACGCAATTATTACGTCAACAATCTAAACCTATATCGTCAATCAATGCATTTCAAATTAAAAGGACTTTTCAA
AACGTCATTAAACAACGTTTCACGTTAAACATGTTATACCCTTATATTGATGAAATTCATATCACAAAAAAGAAAATACT
TGTTGGCATTTATTTCAAAAATGAACCTTTAAACATAATCAATCAAACTACGCAATCATCGATTGCTTAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| ccrA | Staphylococcus aureus COL |
82.405 |
100 |
0.824 |
| ccrA | Staphylococcus aureus N315 |
75.501 |
100 |
0.755 |