Detailed information NTG0198496

Bioinformatically predicted

Overview

• Name: comK/comK1
• Type: Regulator
• Locus tag: BJD96_RS09880
• Genome accession: NZ_CP017460
• Coordinates: 2061598..2062161 (-)
• Length: 187 a.a.
• NCBI ID: WP_096810450.1
• Uniprot ID: A0A291JM98
• Organism: Staphylococcus nepalensis strain JS1
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2048016..2061094	2061598..2062161	flank	504

Gene organization within MGE regions

Location: 2048016..2062161

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJD96_RS09805 (BJD96_09670)	-	2048016..2048438 (-)	423	WP_096810439.1	MarR family transcriptional regulator	-
BJD96_RS09810 (BJD96_09675)	-	2048641..2049645 (+)	1005	WP_096810440.1	acyltransferase family protein	-
BJD96_RS09815 (BJD96_09680)	-	2049766..2050923 (+)	1158	WP_096810441.1	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	-
BJD96_RS09825 (BJD96_09685)	menB	2051764..2052582 (-)	819	WP_096810442.1	1,4-dihydroxy-2-naphthoyl-CoA synthase	-
BJD96_RS09830 (BJD96_09690)	menH	2052575..2053381 (-)	807	WP_096810443.1	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	-
BJD96_RS09835 (BJD96_09695)	menD	2053368..2055050 (-)	1683	WP_096810444.1	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	-
BJD96_RS09840 (BJD96_09700)	-	2055043..2056395 (-)	1353	WP_096810445.1	isochorismate synthase	-
BJD96_RS09845 (BJD96_09705)	-	2056580..2057518 (+)	939	WP_096810446.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
BJD96_RS09850 (BJD96_09710)	-	2057599..2058156 (-)	558	WP_096810447.1	GNAT family N-acetyltransferase	-
BJD96_RS09855 (BJD96_09715)	-	2058332..2058544 (+)	213	WP_046208085.1	TM2 domain-containing protein	-
BJD96_RS15005	-	2058655..2058744 (+)	90	WP_249776154.1	SAR1012 family small protein	-
BJD96_RS09860 (BJD96_09720)	-	2059308..2059979 (+)	672	WP_096810448.1	DUF4352 domain-containing protein	-
BJD96_RS09865 (BJD96_09725)	-	2060000..2061094 (+)	1095	WP_096810449.1	tyrosine-type recombinase/integrase	-
BJD96_RS09880 (BJD96_09740)	comK/comK1	2061598..2062161 (-)	564	WP_096810450.1	competence protein ComK	Regulator

Sequence

Protein

• Length: 187 a.a.
• Molecular weight: 22040.29 Da
• Isoelectric Point: 9.4398

>NTDB_id=198496 BJD96_RS09880 WP_096810450.1 2061598..2062161(-) (comK/comK1) [Staphylococcus nepalensis strain JS1]
MNQPYIIKKGDMALQPCHLAIGQYEGTRVLRYKEDEDVIKERTHKIIDRSCRFYGSSYVFKKEDTIRITGISSKPPILFT
PLFPTYFFPTHSDRKTQNTWINIHYVQSIRSLKDKKCRVNFVDNQSIIVSISAHSMHHQYLNGIYYYYMMDRAARVATFD
PESPIDYTKPQLNIYEALAKYSLFESK

Nucleotide

• Length: 564 bp

>NTDB_id=198496 BJD96_RS09880 WP_096810450.1 2061598..2062161(-) (comK/comK1) [Staphylococcus nepalensis strain JS1]
ATGAATCAACCGTACATTATTAAAAAAGGTGATATGGCATTACAACCTTGCCATCTAGCTATTGGACAATATGAAGGAAC
GCGCGTACTAAGGTATAAAGAAGATGAAGATGTGATTAAAGAACGTACACATAAAATTATTGATCGTTCCTGTAGATTTT
ATGGTAGTAGTTATGTGTTTAAGAAAGAAGACACCATTCGGATCACTGGTATTAGCAGTAAACCCCCAATTCTATTTACT
CCATTATTTCCCACTTATTTTTTTCCAACTCATTCTGATAGAAAAACACAAAATACATGGATTAACATCCATTATGTTCA
AAGTATTAGATCATTAAAAGATAAAAAATGTAGAGTTAACTTTGTTGATAATCAGTCTATCATTGTCAGTATTTCAGCAC
ATAGCATGCATCATCAATATTTAAATGGTATTTATTATTATTATATGATGGACAGAGCAGCTAGGGTTGCAACTTTTGAT
CCGGAATCTCCAATAGATTATACGAAACCACAACTTAATATATACGAAGCATTAGCTAAATACTCTTTGTTTGAAAGCAA
ATAG

Domains

Predicted by InterproScan.

• ComK protein (ComK) (4-152)

3D structure

• AlphaFold DB: A0A291JM98

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comK/comK1	Staphylococcus aureus MW2	53.552	97.861	0.524
comK/comK1	Staphylococcus aureus N315	53.552	97.861	0.524