Detailed information NTG0198461

Bioinformatically predicted

Overview

• Name: comK/comK1
• Type: Regulator
• Locus tag: BJG88_RS09750
• Genome accession: NZ_CP017459
• Coordinates: 2042675..2043238 (-)
• Length: 187 a.a.
• NCBI ID: WP_096810450.1
• Uniprot ID: A0A291JM98
• Organism: Staphylococcus nepalensis strain JS9
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
ICE	2029092..2042171	2042675..2043238	flank	504

Gene organization within MGE regions

Location: 2029092..2043238

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BJG88_RS09670 (BJG88_09545)	-	2029092..2029514 (-)	423	WP_096810439.1	MarR family transcriptional regulator	-
BJG88_RS09675 (BJG88_09550)	-	2029717..2030721 (+)	1005	WP_096810440.1	acyltransferase family protein	-
BJG88_RS09680 (BJG88_09555)	-	2030842..2031999 (+)	1158	WP_096810441.1	aminotransferase class I/II-fold pyridoxal phosphate-dependent enzyme	-
BJG88_RS09690 (BJG88_09560)	menB	2032840..2033658 (-)	819	WP_096810442.1	1,4-dihydroxy-2-naphthoyl-CoA synthase	-
BJG88_RS09695 (BJG88_09565)	menH	2033651..2034457 (-)	807	WP_096810443.1	2-succinyl-6-hydroxy-2, 4-cyclohexadiene-1-carboxylate synthase	-
BJG88_RS09700 (BJG88_09570)	menD	2034444..2036126 (-)	1683	WP_096810444.1	2-succinyl-5-enolpyruvyl-6-hydroxy-3- cyclohexene-1-carboxylic-acid synthase	-
BJG88_RS09705 (BJG88_09575)	-	2036119..2037471 (-)	1353	WP_108909428.1	isochorismate synthase	-
BJG88_RS09710 (BJG88_09580)	-	2037656..2038594 (+)	939	WP_096810446.1	1,4-dihydroxy-2-naphthoate polyprenyltransferase	-
BJG88_RS09715 (BJG88_09585)	-	2038675..2039232 (-)	558	WP_096810447.1	GNAT family N-acetyltransferase	-
BJG88_RS09720 (BJG88_09590)	-	2039408..2039620 (+)	213	WP_046208085.1	TM2 domain-containing protein	-
BJG88_RS14350	-	2039731..2039820 (+)	90	WP_249776154.1	SAR1012 family small protein	-
BJG88_RS09725 (BJG88_09595)	-	2040384..2040689 (+)	306	WP_108909429.1	hypothetical protein	-
BJG88_RS09730 (BJG88_09600)	-	2040652..2041056 (+)	405	WP_159085243.1	DUF4352 domain-containing protein	-
BJG88_RS09735 (BJG88_09605)	-	2041077..2042171 (+)	1095	WP_096810449.1	tyrosine-type recombinase/integrase	-
BJG88_RS09750 (BJG88_09620)	comK/comK1	2042675..2043238 (-)	564	WP_096810450.1	competence protein ComK	Regulator

Sequence

Protein

• Length: 187 a.a.
• Molecular weight: 22040.29 Da
• Isoelectric Point: 9.4398

>NTDB_id=198461 BJG88_RS09750 WP_096810450.1 2042675..2043238(-) (comK/comK1) [Staphylococcus nepalensis strain JS9]
MNQPYIIKKGDMALQPCHLAIGQYEGTRVLRYKEDEDVIKERTHKIIDRSCRFYGSSYVFKKEDTIRITGISSKPPILFT
PLFPTYFFPTHSDRKTQNTWINIHYVQSIRSLKDKKCRVNFVDNQSIIVSISAHSMHHQYLNGIYYYYMMDRAARVATFD
PESPIDYTKPQLNIYEALAKYSLFESK

Nucleotide

• Length: 564 bp

>NTDB_id=198461 BJG88_RS09750 WP_096810450.1 2042675..2043238(-) (comK/comK1) [Staphylococcus nepalensis strain JS9]
ATGAATCAACCGTACATTATTAAAAAAGGTGATATGGCATTACAACCTTGCCATCTAGCTATTGGACAATATGAAGGAAC
GCGCGTACTAAGGTATAAAGAAGATGAAGATGTGATTAAAGAACGTACACATAAAATTATTGATCGTTCCTGTAGATTTT
ATGGTAGTAGTTATGTGTTTAAGAAAGAAGACACCATTCGGATCACTGGTATTAGCAGTAAACCCCCAATTCTATTCACT
CCATTATTTCCCACTTATTTTTTTCCAACTCATTCTGATAGAAAAACACAAAATACATGGATTAACATCCATTATGTTCA
AAGTATTAGATCATTAAAAGATAAAAAATGTAGAGTTAACTTTGTTGATAATCAGTCTATCATTGTCAGTATTTCAGCAC
ATAGCATGCATCATCAATATTTAAATGGTATTTATTATTATTATATGATGGACAGAGCAGCTAGGGTTGCAACTTTTGAT
CCGGAATCTCCAATAGATTATACGAAACCACAACTTAATATATACGAAGCATTAGCTAAATACTCTTTGTTTGAAAGCAA
ATAG

Domains

Predicted by InterproScan.

• ComK protein (ComK) (4-152)

3D structure

• AlphaFold DB: A0A291JM98

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comK/comK1	Staphylococcus aureus MW2	53.552	97.861	0.524
comK/comK1	Staphylococcus aureus N315	53.552	97.861	0.524