Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEC   Type   Machinery gene
Locus tag   BIZ51_RS03460 Genome accession   NZ_CP017458
Coordinates   718424..720631 (-) Length   735 a.a.
NCBI ID   WP_027228446.1    Uniprot ID   A0A2S6F4F0
Organism   Legionella pneumophila subsp. fraseri strain Dallas 1E     
Function   ssDNA transport through the inner membrane (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 713424..725631
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BIZ51_RS03440 (BIZ51_03370) - 713923..715854 (-) 1932 WP_027228442.1 hypothetical protein -
  BIZ51_RS03445 (BIZ51_03375) - 715981..716373 (-) 393 WP_027228443.1 hypothetical protein -
  BIZ51_RS03450 (BIZ51_03380) - 716510..716887 (+) 378 WP_027228444.1 hypothetical protein -
  BIZ51_RS03455 (BIZ51_03385) - 717087..718376 (+) 1290 WP_027228445.1 tetratricopeptide repeat protein -
  BIZ51_RS03460 (BIZ51_03390) comEC 718424..720631 (-) 2208 WP_027228446.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  BIZ51_RS03465 (BIZ51_03395) pilE 720709..721158 (-) 450 WP_027228447.1 type IV pilin protein Machinery gene
  BIZ51_RS03470 (BIZ51_03400) - 721170..724679 (-) 3510 WP_027228448.1 pilus assembly protein -
  BIZ51_RS03475 (BIZ51_03405) - 724692..725204 (-) 513 WP_027228449.1 pilus assembly protein -

Sequence

Protein


Download         Length: 735 a.a.        Molecular weight: 83187.83 Da        Isoelectric Point: 9.5930

>NTDB_id=198395 BIZ51_RS03460 WP_027228446.1 718424..720631(-) (comEC) [Legionella pneumophila subsp. fraseri strain Dallas 1E]
MEIFCFLIGVLYAYTDNIYLTIAIPLLFYITPRYPIVLFFLAGWGFALIHQWIVSPKGMPDTQVITQVQLEGTIASIPMQ
RPNKTQFHFAIEKINNNPAQGLIQLNWYNKPPILRAGQRWQLSVKLKKPRNFRNPGGFNYVRYLAARHIHWAGYIRYGNN
KLINNHPPSFSWLTLREKIGDALTKLAPDMETAGIIEALTLNVTHHISSEHWNLFRRTGTIHLFGISGEHIALVSGIFFI
VIRWMWSMSYRCCLFLPANTIASIGGLLAALPYAFLAGFEPPVQRALIGCVLYTIYAIGKQRFTPWQIWRYALFLVLCIE
PHAVFLQGFYFSFLAVACLLLTHQRWPLKNYKKTLALQLSCLIGLMPLTLHWYSYGSINGFLANLFAIPLVSFLIVPLAL
MTMIMSPFDWSWILMKPLAWLVALLLQGLTYVEQIAGINITWSITSGTMMLAMTAGLFLRVLLPVKPFKHLAILWIIIPL
FPPRTAIYPGEALINVLDVGQGLAVAIQTQHHVLLYDTGDSFFQGSDLGQMAIIPFFRSAEIKTIDTIVISHPDKDHKGG
LNSLEKEMQVNQLIVNDPYFYKRGSNCHSYPQWQWDGVSFRFLPIKESFTKKNNNSCILQVSNSAGRVLLTGDIEKAAED
YLVRNYGSELASEILVVPHHGSKTSSSYRFLLEVNPLYAIASLGFDNRFKFPHVKTLQSMKTLGITFLRTDDCGMAGIKL
PASGKINKPTCMQAE

Nucleotide


Download         Length: 2208 bp        

>NTDB_id=198395 BIZ51_RS03460 WP_027228446.1 718424..720631(-) (comEC) [Legionella pneumophila subsp. fraseri strain Dallas 1E]
ATGGAAATTTTTTGCTTTTTAATAGGCGTACTTTATGCCTATACCGATAATATTTATCTAACTATTGCGATTCCTTTACT
CTTTTATATCACACCAAGATATCCAATTGTCCTGTTCTTCCTGGCCGGGTGGGGCTTTGCCCTGATTCACCAGTGGATTG
TATCACCCAAGGGAATGCCTGATACGCAAGTAATCACTCAAGTCCAATTGGAAGGAACAATTGCTTCCATCCCCATGCAA
CGTCCTAACAAAACCCAATTCCATTTTGCAATTGAAAAAATTAATAATAATCCTGCTCAAGGCTTAATCCAATTAAACTG
GTACAACAAACCACCTATCTTACGAGCCGGTCAGCGATGGCAACTTTCCGTAAAACTAAAAAAACCTCGTAATTTCCGCA
ACCCCGGAGGTTTTAATTATGTACGCTACCTGGCGGCTCGTCATATCCATTGGGCTGGTTATATTCGTTATGGGAATAAT
AAATTAATTAACAATCACCCCCCCTCTTTCAGTTGGTTAACACTACGTGAAAAAATAGGGGATGCTCTGACCAAACTGGC
ACCTGATATGGAAACAGCAGGCATTATCGAAGCATTGACGTTAAATGTAACTCACCATATCAGTTCAGAACATTGGAATT
TATTCCGACGAACGGGAACAATACATTTATTTGGGATATCAGGAGAGCACATCGCTCTGGTATCTGGCATTTTCTTTATC
GTGATAAGATGGATGTGGTCAATGAGCTATCGCTGTTGTTTATTCTTACCAGCCAATACCATAGCGAGTATCGGTGGATT
ACTAGCCGCCTTGCCCTATGCTTTTTTAGCAGGGTTTGAGCCTCCTGTACAGCGTGCTTTAATTGGTTGTGTACTTTACA
CAATATACGCCATTGGAAAACAACGCTTTACGCCATGGCAAATATGGAGATATGCCTTATTTTTAGTCTTGTGCATTGAA
CCCCACGCTGTATTCCTGCAAGGATTTTATTTTTCATTTCTTGCGGTGGCTTGTCTTCTATTGACTCACCAACGTTGGCC
ACTGAAAAACTATAAAAAGACACTTGCATTACAATTAAGCTGCCTTATTGGATTGATGCCTTTAACGCTCCATTGGTACT
CCTATGGCTCTATCAATGGATTTCTTGCCAATTTATTTGCCATACCTTTAGTCAGCTTTCTGATAGTACCCTTGGCTTTA
ATGACTATGATTATGAGTCCATTTGATTGGTCATGGATATTAATGAAACCATTGGCCTGGCTTGTTGCCCTGTTACTGCA
AGGGTTGACGTATGTTGAGCAAATAGCAGGGATCAATATCACCTGGTCCATCACCTCAGGAACAATGATGCTCGCTATGA
CAGCAGGTCTGTTTTTAAGAGTATTATTACCTGTCAAGCCATTCAAACACTTGGCTATCCTTTGGATTATCATTCCCTTA
TTTCCGCCCCGTACTGCAATTTACCCAGGAGAAGCATTAATTAATGTTTTGGATGTTGGACAAGGGCTGGCTGTTGCGAT
ACAAACGCAACATCATGTTTTACTCTACGATACGGGAGATTCATTTTTTCAAGGCAGTGATTTAGGGCAAATGGCAATAA
TACCTTTTTTTAGATCAGCTGAAATAAAAACCATTGATACCATTGTGATAAGCCATCCTGATAAAGATCATAAAGGTGGA
TTAAATTCCCTTGAAAAAGAGATGCAAGTCAATCAATTAATAGTGAATGATCCCTATTTTTATAAGCGTGGAAGCAATTG
TCATTCATACCCTCAATGGCAATGGGATGGGGTAAGTTTTCGTTTTTTACCCATCAAAGAGTCTTTCACTAAAAAAAATA
ACAACTCTTGTATTTTACAAGTAAGTAATTCAGCTGGCAGAGTTTTATTAACGGGAGATATTGAAAAAGCGGCTGAAGAC
TACCTGGTAAGAAACTACGGCAGTGAGCTGGCATCTGAAATTTTAGTTGTTCCTCATCATGGGAGTAAGACTTCTTCATC
TTATCGATTTTTACTGGAAGTAAACCCACTTTATGCGATTGCATCGTTGGGATTTGATAATCGCTTCAAATTTCCACACG
TCAAAACGTTGCAAAGCATGAAAACATTAGGTATCACTTTTTTAAGAACAGACGACTGCGGCATGGCAGGAATCAAACTA
CCTGCATCAGGTAAAATTAACAAACCAACCTGTATGCAGGCTGAATGA

Domains

Predicted by InterproScan.

Competence protein (Competence)

(199-464)

Domain of unknown function (DUF4131) (DUF4131)

(31-158)

Metallo-beta-lactamase superfamily (Lactamase_B)

(498-579)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2S6F4F0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEC Legionella pneumophila strain Lp02

95.095

99.864

0.95
  comEC Legionella pneumophila strain ERS1305867

94.558

100

0.946

Multiple sequence alignment