Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   BB162_RS01935 Genome accession   NZ_CP021869
Coordinates   320633..321274 (+) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain SG-M6     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 315633..326274
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BB162_RS01915 (BB162_01915) - 316078..316815 (+) 738 WP_000406233.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  BB162_RS01920 (BB162_01920) pknB 316815..318770 (+) 1956 WP_000614565.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  BB162_RS01925 (BB162_01925) liaF 318929..319624 (+) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  BB162_RS01930 (BB162_01930) - 319621..320640 (+) 1020 WP_000716168.1 sensor histidine kinase -
  BB162_RS01935 (BB162_01935) vraR 320633..321274 (+) 642 WP_000357891.1 response regulator transcription factor Regulator
  BB162_RS01940 (BB162_01940) - 321316..322716 (+) 1401 WP_000339135.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  BB162_RS01945 (BB162_01945) - 322718..323074 (+) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  BB162_RS01950 (BB162_01950) - 323120..323896 (-) 777 WP_000180538.1 glycyl-radical enzyme activating protein -
  BB162_RS01955 (BB162_01955) - 324017..324772 (+) 756 WP_001080743.1 DeoR/GlpR family DNA-binding transcription regulator -
  BB162_RS01960 (BB162_01960) - 324891..325874 (+) 984 WP_000764461.1 sugar-binding transcriptional regulator -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=197502 BB162_RS01935 WP_000357891.1 320633..321274(+) (vraR) [Streptococcus agalactiae strain SG-M6]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=197502 BB162_RS01935 WP_000357891.1 320633..321274(+) (vraR) [Streptococcus agalactiae strain SG-M6]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAAGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCACTGGAGTTACGTCCAGACGTTGTTG
TTATGGATTTAGTAATGCCTGAAATGGACGGTGTAGAAGCAACCTTAGCATTGTTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGACAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGTGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATCCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTGGCAGATCGAACTCAAGCGGTTGTCTATGCTTTCCAACACCATTTGGTACCACAAGATGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394