Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   WH25_RS06540 Genome accession   NZ_CP017295
Coordinates   1364740..1365969 (-) Length   409 a.a.
NCBI ID   WP_008808666.1    Uniprot ID   A0AAP2K4Q6
Organism   Streptococcus gordonii strain IE35     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1359740..1370969
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS06515 (WH25_06515) - 1360681..1361421 (-) 741 WP_046165951.1 esterase family protein -
  WH25_RS06520 (WH25_06520) - 1361471..1362295 (-) 825 WP_045502979.1 alpha/beta hydrolase -
  WH25_RS06525 (WH25_06525) - 1362389..1363186 (-) 798 WP_046165592.1 formate/nitrite transporter family protein -
  WH25_RS06530 (WH25_06530) - 1363314..1364003 (-) 690 WP_045502983.1 glucosaminidase domain-containing protein -
  WH25_RS06535 (WH25_06535) yihA 1364137..1364730 (-) 594 WP_045502985.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  WH25_RS06540 (WH25_06540) clpX 1364740..1365969 (-) 1230 WP_008808666.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  WH25_RS06545 (WH25_06545) - 1366179..1366691 (-) 513 WP_008808665.1 dihydrofolate reductase -
  WH25_RS06550 (WH25_06550) - 1366837..1367337 (-) 501 WP_046165591.1 hypothetical protein -
  WH25_RS06555 (WH25_06555) - 1367468..1368307 (-) 840 WP_046165590.1 thymidylate synthase -
  WH25_RS06560 (WH25_06560) - 1368406..1369365 (-) 960 WP_045774034.1 ROK family glucokinase -
  WH25_RS06565 (WH25_06565) - 1369541..1370386 (-) 846 WP_046165589.1 alpha/beta hydrolase -

Sequence

Protein


Download         Length: 409 a.a.        Molecular weight: 45650.21 Da        Isoelectric Point: 4.4870

>NTDB_id=197421 WH25_RS06540 WP_008808666.1 1364740..1365969(-) (clpX) [Streptococcus gordonii strain IE35]
MPTNRNEEMMVYCSFCGKNQDEVQKIIAGNNAFICNECVELAQEIIREELAEEVLADLSEVPKPQELLHILNHYVIGQER
AKRALAVAVYNHYKRINFHDSREEDDVELQKSNILMIGPTGSGKTFLAQTLARSLNVPFAIADATALTEAGYVGEDVENI
LLKLLQAADFNIERAERGIIYVDEIDKIAKKSENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPQQEMIQVDTK
NILFIVGGAFDGIEEIVKQRLGEKIIGFGQNNKAIDENESYMQAIIAEDIQKFGIIPELIGRLPVFAALEQLTVDDLVRI
LREPKNALVKQYQALLSYDDVKLEFDDDALQEIANKAIERKTGARGLRSIIEETMMDVMFEVPSKENVKLVRITKEAVDG
TDKPILETA

Nucleotide


Download         Length: 1230 bp        

>NTDB_id=197421 WH25_RS06540 WP_008808666.1 1364740..1365969(-) (clpX) [Streptococcus gordonii strain IE35]
ATGCCTACCAATCGTAATGAAGAGATGATGGTATATTGTTCATTTTGTGGGAAGAACCAAGATGAAGTTCAAAAGATTAT
TGCAGGTAATAACGCTTTTATTTGTAATGAGTGTGTAGAATTAGCACAAGAAATTATCCGTGAAGAATTAGCCGAAGAAG
TCTTAGCTGACTTGTCAGAGGTTCCAAAACCTCAAGAATTATTGCATATTCTAAACCATTATGTCATCGGTCAAGAGCGC
GCTAAAAGAGCGCTAGCTGTAGCAGTATATAATCACTACAAGCGCATTAATTTTCACGACAGCCGTGAAGAAGATGATGT
TGAATTGCAAAAATCAAATATCTTAATGATAGGTCCAACGGGTTCTGGAAAAACTTTTCTTGCTCAGACCTTGGCTAGAA
GTTTAAATGTACCGTTTGCGATTGCTGATGCGACAGCTTTAACAGAGGCTGGTTATGTCGGAGAAGATGTAGAAAATATT
CTTTTAAAACTTTTGCAGGCGGCTGATTTCAATATTGAACGTGCAGAACGAGGAATCATCTACGTAGATGAGATTGATAA
GATCGCTAAAAAGAGTGAAAATGTTTCTATCACGCGCGATGTATCAGGTGAAGGAGTACAGCAAGCTCTCTTAAAAATTA
TTGAAGGTACTGTAGCAAGTGTTCCGCCTCAAGGAGGTCGCAAGCATCCGCAGCAAGAAATGATTCAGGTTGATACCAAA
AATATTCTTTTCATCGTTGGTGGTGCCTTTGATGGGATTGAAGAAATTGTAAAACAACGTTTGGGCGAGAAAATTATTGG
TTTTGGTCAAAATAACAAAGCTATCGATGAAAACGAGTCCTACATGCAAGCTATTATTGCTGAAGATATTCAAAAATTTG
GAATTATCCCTGAATTAATTGGTCGTTTGCCTGTTTTTGCTGCTCTGGAACAACTGACTGTAGACGACTTGGTTCGTATT
CTTCGCGAGCCAAAGAATGCTTTGGTTAAACAATACCAGGCTCTCTTGTCTTACGATGATGTTAAACTAGAGTTTGATGA
TGATGCTTTACAGGAAATCGCGAACAAGGCCATTGAGCGCAAAACTGGGGCTCGTGGTCTACGTTCTATCATCGAAGAAA
CCATGATGGATGTTATGTTTGAAGTTCCAAGTAAAGAAAATGTGAAACTTGTCAGAATCACGAAGGAAGCCGTTGATGGT
ACGGATAAACCAATTTTAGAGACTGCTTGA

Domains

Predicted by InterproScan.

AAA domain (Cdc48 subfamily) (AAA_2)

(110-305)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(312-389)

ClpX C4-type zinc finger (zf-C4_ClpX)

(12-48)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

85.575

100

0.856
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.105

98.044

0.57

Multiple sequence alignment