Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   WH25_RS03390 Genome accession   NZ_CP017295
Coordinates   709776..710465 (+) Length   229 a.a.
NCBI ID   WP_012000010.1    Uniprot ID   A0AAP2NYS9
Organism   Streptococcus gordonii strain IE35     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 704776..715465
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  WH25_RS03370 (WH25_03370) - 705122..705991 (-) 870 WP_046165109.1 Rgg/GadR/MutR family transcriptional regulator -
  WH25_RS03375 (WH25_03375) - 706090..706620 (+) 531 WP_045505786.1 YceD family protein -
  WH25_RS03380 (WH25_03380) - 706722..708203 (+) 1482 WP_008808506.1 flotillin family protein -
  WH25_RS03385 (WH25_03385) gndA 708339..709763 (+) 1425 WP_008808507.1 NADP-dependent phosphogluconate dehydrogenase -
  WH25_RS03390 (WH25_03390) covR 709776..710465 (+) 690 WP_012000010.1 response regulator transcription factor Regulator
  WH25_RS03395 (WH25_03395) - 710825..713017 (+) 2193 WP_046165110.1 PTS transporter subunit IIBC -
  WH25_RS03400 (WH25_03400) - 713035..713850 (+) 816 WP_046165111.1 endonuclease/exonuclease/phosphatase family protein -
  WH25_RS03405 (WH25_03405) - 713993..714409 (-) 417 WP_046165112.1 hypothetical protein -
  WH25_RS03410 (WH25_03410) - 714559..714993 (-) 435 WP_046165199.1 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26261.28 Da        Isoelectric Point: 5.1919

>NTDB_id=197402 WH25_RS03390 WP_012000010.1 709776..710465(+) (covR) [Streptococcus gordonii strain IE35]
MAKRILLVENEKNLARFIMLELQKESYQVDLAETGQEGLALAKENDYDLLLLNNQFADGTAFAFAQQLSLLKPAAVIIVM
VSREEIADSAEEIQQFAVSYMVKPFIISDLVDKISAIFRGRDFIDQKCSQLKVPTAYRNLRVDLKNHTVYRGEEIIALTR
REYDLLVTLMSSNKVMSREQLLDRVWKYESASETNIVDVYIRYLRSKIDLPGQESYIKTVRGIGYSMQG

Nucleotide


Download         Length: 690 bp        

>NTDB_id=197402 WH25_RS03390 WP_012000010.1 709776..710465(+) (covR) [Streptococcus gordonii strain IE35]
ATGGCGAAGCGGATTTTATTAGTTGAAAATGAAAAGAATCTAGCACGATTTATCATGCTGGAATTACAAAAGGAAAGTTA
TCAAGTAGACCTAGCGGAAACAGGGCAAGAGGGACTAGCTCTAGCAAAGGAAAACGATTATGATTTACTTTTACTAAATA
ATCAGTTTGCTGATGGAACAGCCTTTGCCTTTGCTCAACAATTAAGTTTATTAAAACCAGCTGCAGTAATCATTGTAATG
GTGAGCCGAGAGGAGATTGCGGATTCGGCTGAAGAGATTCAGCAGTTTGCAGTTTCTTATATGGTAAAACCCTTTATTAT
TAGTGATCTGGTTGATAAAATATCTGCTATTTTTCGTGGACGAGATTTTATTGATCAGAAATGTAGCCAGTTAAAAGTTC
CTACTGCTTATCGTAATTTGCGGGTTGATTTGAAAAATCATACGGTTTATCGAGGGGAAGAAATTATTGCTTTGACGAGA
CGAGAGTACGATTTACTAGTGACTCTAATGAGCAGTAATAAGGTGATGAGCCGTGAGCAACTGTTAGATCGAGTGTGGAA
GTATGAAAGTGCATCTGAGACTAATATAGTGGATGTATATATTCGTTACCTCCGTAGTAAAATCGATCTTCCAGGACAAG
AAAGTTATATTAAAACCGTTCGTGGAATTGGTTATTCCATGCAGGGTTAA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(5-114)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-226)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

51.77

98.69

0.511
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.737

99.563

0.445

Multiple sequence alignment