Detailed information    

insolico Bioinformatically predicted

Overview

Name   dsbA2   Type   Machinery gene
Locus tag   BFO62_RS11050 Genome accession   NZ_CP017257
Coordinates   1916952..1917647 (-) Length   231 a.a.
NCBI ID   WP_002215704.1    Uniprot ID   Q7DDR6
Organism   Neisseria meningitidis strain COL-201504-11     
Function   DNA binding and uptake; interact with PilQ (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1900483..1918477 1916952..1917647 within 0


Gene organization within MGE regions


Location: 1900483..1918477
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFO62_RS10935 - 1900483..1901234 (+) 752 WP_096001759.1 IS5-like element IS1301 family transposase -
  BFO62_RS14120 (BFO62_09885) - 1901216..1901698 (-) 483 WP_061729868.1 hypothetical protein -
  BFO62_RS14125 - 1901866..1902030 (-) 165 WP_002239497.1 hypothetical protein -
  BFO62_RS10955 (BFO62_09890) - 1902980..1903225 (-) 246 WP_002224299.1 hypothetical protein -
  BFO62_RS10960 (BFO62_09900) - 1903337..1903765 (+) 429 WP_002212270.1 CopD family protein -
  BFO62_RS10965 (BFO62_09905) - 1903777..1904253 (+) 477 WP_002224298.1 CYTH domain-containing protein -
  BFO62_RS10975 (BFO62_09910) - 1904603..1905091 (-) 489 WP_002224297.1 dihydrofolate reductase -
  BFO62_RS10980 (BFO62_09915) aroG 1905159..1906214 (-) 1056 WP_002216371.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  BFO62_RS13330 - 1906376..1906603 (-) 228 WP_153310284.1 hypothetical protein -
  BFO62_RS10990 (BFO62_09920) - 1906877..1907134 (+) 258 WP_002247771.1 hypothetical protein -
  BFO62_RS13675 - 1907183..1907287 (-) 105 Protein_1853 IS1595 family transposase -
  BFO62_RS13685 (BFO62_09930) comE 1907962..1908426 (-) 465 WP_011798959.1 ComEA family DNA-binding protein Machinery gene
  BFO62_RS11040 (BFO62_09965) - 1914224..1915030 (-) 807 WP_076612651.1 inner membrane protein YpjD -
  BFO62_RS11045 (BFO62_09970) ffh 1915251..1916621 (+) 1371 WP_076612650.1 signal recognition particle protein -
  BFO62_RS11050 (BFO62_09975) dsbA2 1916952..1917647 (-) 696 WP_002215704.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  BFO62_RS11055 (BFO62_09980) - 1917818..1918477 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 231 a.a.        Molecular weight: 25419.90 Da        Isoelectric Point: 5.1502

>NTDB_id=197018 BFO62_RS11050 WP_002215704.1 1916952..1917647(-) (dsbA2) [Neisseria meningitidis strain COL-201504-11]
MKLKTLALTSLTLLALAACSKQAETSVPADSAQSSSSAPAAPAELNEGVNYTVLSTPIPQQQAGKIEVLEFFGYFCPHCA
HLEPVLSEHIKTFKDDTYMRREHVVWGDEMKPLARLAAAVEMAGESDKANSHIFDAMVNQKINLADTDTLKKWLSEQTAF
DGKKVLAAFEAPESQARAAQMEELTNKFQISGTPTVIVGGKYQVEFKDWQSGMTTIDQLVDKVREEQKKPQ

Nucleotide


Download         Length: 696 bp        

>NTDB_id=197018 BFO62_RS11050 WP_002215704.1 1916952..1917647(-) (dsbA2) [Neisseria meningitidis strain COL-201504-11]
ATGAAACTGAAAACCTTAGCTTTGACTTCATTGACCCTGTTGGCATTGGCCGCTTGTAGCAAACAGGCTGAAACCAGTGT
TCCGGCAGACAGCGCCCAAAGCAGCTCATCTGCTCCGGCAGCCCCTGCTGAGTTGAACGAAGGTGTGAACTACACTGTAT
TGTCTACGCCTATTCCGCAACAGCAGGCCGGTAAAATCGAAGTATTGGAATTTTTCGGCTACTTCTGCCCGCATTGCGCC
CATCTTGAGCCGGTCTTGAGCGAGCACATCAAAACGTTTAAAGACGATACCTATATGCGCCGGGAGCATGTCGTGTGGGG
TGATGAAATGAAACCTTTGGCACGTTTGGCGGCCGCAGTGGAAATGGCCGGTGAATCAGATAAAGCCAACAGCCATATTT
TCGATGCGATGGTTAATCAAAAAATCAATCTGGCCGATACCGATACCCTGAAAAAATGGCTGTCCGAGCAAACAGCGTTT
GACGGCAAAAAAGTATTGGCTGCATTTGAGGCTCCTGAAAGCCAAGCGCGTGCGGCTCAAATGGAAGAGTTGACCAATAA
ATTCCAAATCAGCGGCACACCGACTGTGATTGTCGGCGGCAAATACCAAGTTGAATTTAAAGACTGGCAGTCTGGTATGA
CCACGATTGACCAGTTGGTGGATAAAGTACGCGAAGAGCAGAAAAAGCCGCAATAA

Domains

Predicted by InterproScan.

Thioredoxin (Thioredoxin_4)

(65-212)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q7DDR6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dsbA2 Neisseria meningitidis MC58

100

100

1
  dsbA1 Neisseria meningitidis MC58

71.245

100

0.719

Multiple sequence alignment