Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CCZ24_RS08860 Genome accession   NZ_CP021773
Coordinates   1748971..1749612 (-) Length   213 a.a.
NCBI ID   WP_000357891.1    Uniprot ID   -
Organism   Streptococcus agalactiae strain B105     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1743971..1754612
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CCZ24_RS08835 (CCZ24_08685) - 1744371..1745354 (-) 984 WP_000764461.1 sugar-binding transcriptional regulator -
  CCZ24_RS08840 (CCZ24_08690) - 1745473..1746228 (-) 756 WP_001080743.1 DeoR/GlpR family DNA-binding transcription regulator -
  CCZ24_RS08845 (CCZ24_08695) - 1746349..1747125 (+) 777 WP_000180538.1 glycyl-radical enzyme activating protein -
  CCZ24_RS08850 (CCZ24_08700) - 1747171..1747527 (-) 357 WP_000689608.1 S1 RNA-binding domain-containing protein -
  CCZ24_RS08855 (CCZ24_08705) - 1747529..1748929 (-) 1401 WP_000339135.1 Cof-type HAD-IIB family hydrolase -
  CCZ24_RS08860 (CCZ24_08710) vraR 1748971..1749612 (-) 642 WP_000357891.1 response regulator transcription factor Regulator
  CCZ24_RS08865 (CCZ24_08715) - 1749605..1750624 (-) 1020 WP_000716168.1 sensor histidine kinase -
  CCZ24_RS08870 (CCZ24_08720) liaF 1750621..1751316 (-) 696 WP_000714456.1 cell wall-active antibiotics response protein LiaF -
  CCZ24_RS08875 (CCZ24_08725) pknB 1751475..1753430 (-) 1956 WP_000614565.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  CCZ24_RS08880 (CCZ24_08730) - 1753430..1754167 (-) 738 WP_000406233.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23634.35 Da        Isoelectric Point: 5.0159

>NTDB_id=196244 CCZ24_RS08860 WP_000357891.1 1748971..1749612(-) (vraR) [Streptococcus agalactiae strain B105]
MDKIKIVLVDDHEMVRLGLKSFLNLQADVEVIGEASNGLEGIKKALELRPDVVVMDLVMPEMDGVEATLALLKDWPEAAI
LVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNAIRKVARGEQAIENEVDKKIKAHDKCPALHEGLTARERDILNLLA
KGYDNQRIADELFISLKTVKTHVSNILGKLNVADRTQAVVYAFQHHLVPQDDE

Nucleotide


Download         Length: 642 bp        

>NTDB_id=196244 CCZ24_RS08860 WP_000357891.1 1748971..1749612(-) (vraR) [Streptococcus agalactiae strain B105]
ATGGATAAAATAAAAATTGTACTTGTTGATGACCATGAGATGGTTCGTCTCGGTTTAAAAAGTTTTTTAAACTTACAAGC
TGATGTTGAAGTAATAGGTGAAGCCTCAAATGGTTTAGAAGGCATAAAAAAAGCACTGGAGTTACGTCCAGACGTTGTTG
TTATGGATTTAGTAATGCCTGAAATGGACGGTGTAGAAGCAACCTTAGCATTGTTGAAGGATTGGCCAGAAGCTGCTATT
TTAGTCTTAACATCTTACTTGGACAATGAAAAAATTTACCCTGTTATTGAAGCAGGTGCCAAAGGCTATATGTTAAAGAC
CTCAAGTGCAGCAGAGATTCTTAATGCCATTCGTAAAGTTGCAAGGGGAGAACAAGCTATTGAAAATGAAGTAGATAAGA
AAATTAAGGCTCATGATAAATGTCCAGCTTTACATGAGGGCTTAACAGCAAGGGAACGTGATATCCTTAATTTATTAGCC
AAAGGTTATGACAATCAAAGGATTGCTGATGAATTATTTATCTCGTTAAAGACTGTTAAAACTCATGTTTCTAATATTTT
GGGAAAACTAAATGTGGCAGATCGAACTCAAGCGGTTGTCTATGCTTTCCAACACCATTTGGTACCACAAGATGATGAAT
AA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(6-118)

Bacterial regulatory proteins, luxR family (GerE)

(148-202)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.369

96.714

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

37.168

100

0.394