Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   BFP66_RS08035 Genome accession   NZ_CP017142
Coordinates   1615759..1616448 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain GZ0565     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1610759..1621448
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BFP66_RS08010 (BFP66_08010) - 1611076..1611789 (-) 714 WP_063725343.1 NADPH-dependent oxidoreductase -
  BFP66_RS08015 (BFP66_08015) dnaI 1611786..1612685 (-) 900 WP_024396095.1 primosomal protein DnaI -
  BFP66_RS08020 (BFP66_08020) - 1612685..1613836 (-) 1152 WP_024396094.1 replication initiation/membrane attachment protein -
  BFP66_RS08025 (BFP66_08025) nrdR 1613823..1614314 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  BFP66_RS08030 (BFP66_08030) - 1614386..1615516 (-) 1131 WP_014636113.1 AI-2E family transporter -
  BFP66_RS08035 (BFP66_08035) covR 1615759..1616448 (-) 690 WP_012027645.1 DNA-binding response regulator Regulator
  BFP66_RS08040 (BFP66_08040) gndA 1616530..1617957 (-) 1428 WP_014638518.1 NADP-dependent phosphogluconate dehydrogenase -
  BFP66_RS08045 (BFP66_08045) - 1618054..1618593 (-) 540 WP_014736258.1 YceD family protein -
  BFP66_RS08050 (BFP66_08050) trxB 1618603..1619520 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  BFP66_RS08055 (BFP66_08055) - 1619534..1619758 (-) 225 WP_002936682.1 DUF4059 family protein -
  BFP66_RS08060 (BFP66_08060) - 1619776..1621119 (-) 1344 WP_024396093.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=195967 BFP66_RS08035 WP_012027645.1 1615759..1616448(-) (covR) [Streptococcus suis strain GZ0565]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=195967 BFP66_RS08035 WP_012027645.1 1615759..1616448(-) (covR) [Streptococcus suis strain GZ0565]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGCAAGGAATTGGCTACAGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTTGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAGCAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGGACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATTAAAACGGTTCGTGGTGTCGGATATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment