Detailed information
Bioinformatically predicted
Overview
| Name | dprA | Type | Machinery gene |
| Locus tag | FORC45_RS06175 | Genome accession | NZ_CP017115 |
| Coordinates | 1218844..1219716 (+) | Length | 290 a.a. |
| NCBI ID | WP_000593192.1 | Uniprot ID | A0A140HKN1 |
| Organism | Staphylococcus aureus strain FORC_045 | ||
| Function | ssDNA binding; loading RecA onto ssDNA (predicted from homology) DNA processing |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 1193918..1248503 | 1218844..1219716 | within | 0 |
Gene organization within MGE regions
Location: 1193918..1248503
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| FORC45_RS06045 (FORC45_1120) | fapR | 1195444..1196016 (+) | 573 | WP_001548538.1 | transcription factor FapR | - |
| FORC45_RS06050 (FORC45_1121) | plsX | 1196021..1197007 (+) | 987 | WP_000239748.1 | phosphate acyltransferase PlsX | - |
| FORC45_RS06055 | fabD | 1197000..1197923 (+) | 924 | Protein_1131 | ACP S-malonyltransferase | - |
| FORC45_RS06060 (FORC45_1124) | fabG | 1197916..1198650 (+) | 735 | WP_000167269.1 | 3-oxoacyl-[acyl-carrier-protein] reductase | - |
| FORC45_RS06070 (FORC45_1125) | - | 1199020..1199253 (+) | 234 | WP_000426914.1 | acyl carrier protein | - |
| FORC45_RS06075 (FORC45_1126) | rnc | 1199369..1200099 (+) | 731 | Protein_1134 | ribonuclease III | - |
| FORC45_RS14910 (FORC45_1127) | - | 1200246..1203229 (+) | 2984 | Protein_1135 | AAA family ATPase | - |
| FORC45_RS14875 | - | 1203478..1204070 (+) | 593 | Protein_1136 | signal recognition particle receptor subunit alpha | - |
| FORC45_RS14880 | - | 1204224..1204310 (+) | 87 | WP_335696440.1 | hypothetical protein | - |
| FORC45_RS14780 | - | 1204482..1204776 (+) | 295 | Protein_1138 | putative DNA-binding protein | - |
| FORC45_RS06110 | ffh | 1204802..1206162 (+) | 1361 | Protein_1139 | signal recognition particle protein | - |
| FORC45_RS06115 (FORC45_1130) | rpsP | 1206590..1206864 (+) | 275 | Protein_1140 | 30S ribosomal protein S16 | - |
| FORC45_RS06120 (FORC45_1131) | rimM | 1207051..1207553 (+) | 503 | Protein_1141 | ribosome maturation factor RimM | - |
| FORC45_RS06125 (FORC45_1133) | trmD | 1207553..1208287 (+) | 735 | Protein_1142 | tRNA (guanosine(37)-N1)-methyltransferase TrmD | - |
| FORC45_RS06130 (FORC45_1134) | rplS | 1208390..1208739 (+) | 350 | Protein_1143 | 50S ribosomal protein L19 | - |
| FORC45_RS06140 (FORC45_1135) | yfhO | 1209208..1211814 (-) | 2607 | WP_000915244.1 | lipoteichoic acid-specific glycosyltransferase YfhO | - |
| FORC45_RS06145 (FORC45_1136) | ylqF | 1212215..1213099 (+) | 885 | WP_000236715.1 | ribosome biogenesis GTPase YlqF | - |
| FORC45_RS06150 (FORC45_1137) | - | 1213083..1213849 (+) | 767 | Protein_1146 | ribonuclease HII | - |
| FORC45_RS06155 (FORC45_1138) | sucC | 1213958..1215124 (+) | 1167 | WP_001020801.1 | ADP-forming succinate--CoA ligase subunit beta | - |
| FORC45_RS06160 (FORC45_1139) | sucD | 1215146..1216054 (+) | 909 | WP_000110251.1 | succinate--CoA ligase subunit alpha | - |
| FORC45_RS06165 (FORC45_1140) | - | 1216281..1217399 (+) | 1119 | WP_001041666.1 | LysM peptidoglycan-binding domain-containing protein | - |
| FORC45_RS06170 (FORC45_1141) | fmhC | 1217427..1218671 (+) | 1245 | WP_000672867.1 | FemA/FemB family glycyltransferase FmhC | - |
| FORC45_RS06175 (FORC45_1142) | dprA | 1218844..1219716 (+) | 873 | WP_000593192.1 | DNA-processing protein DprA | Machinery gene |
| FORC45_RS06180 (FORC45_1143) | topA | 1219890..1221965 (+) | 2076 | WP_001557331.1 | type I DNA topoisomerase | - |
| FORC45_RS06185 (FORC45_1144) | trmFO | 1222121..1223428 (+) | 1308 | WP_000195254.1 | methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO | - |
| FORC45_RS06190 (FORC45_1145) | xerC | 1223845..1224741 (+) | 897 | WP_001015602.1 | tyrosine recombinase XerC | - |
| FORC45_RS06195 (FORC45_1146) | hslV | 1224738..1225283 (+) | 546 | WP_000072681.1 | ATP-dependent protease subunit HslV | - |
| FORC45_RS06200 (FORC45_1147) | hslU | 1225349..1226752 (+) | 1404 | WP_000379054.1 | ATP-dependent protease ATPase subunit HslU | - |
| FORC45_RS06205 (FORC45_1148) | codY | 1226777..1227550 (+) | 774 | WP_000055337.1 | GTP-sensing pleiotropic transcriptional regulator CodY | - |
| FORC45_RS06210 | - | 1227601..1227693 (+) | 93 | WP_031788481.1 | hypothetical protein | - |
| FORC45_RS06215 (FORC45_1149) | rpsB | 1227892..1228659 (+) | 768 | WP_000268484.1 | 30S ribosomal protein S2 | - |
| FORC45_RS06220 (FORC45_1150) | - | 1228693..1228806 (+) | 114 | WP_001789890.1 | hypothetical protein | - |
| FORC45_RS06225 (FORC45_1151) | tsf | 1228841..1229722 (+) | 882 | WP_000201387.1 | translation elongation factor Ts | - |
| FORC45_RS06230 (FORC45_1152) | pyrH | 1229859..1230581 (+) | 723 | WP_000057330.1 | UMP kinase | - |
| FORC45_RS06235 (FORC45_1153) | frr | 1230600..1231154 (+) | 555 | WP_001280006.1 | ribosome recycling factor | - |
| FORC45_RS06240 (FORC45_1154) | - | 1231527..1232297 (+) | 771 | WP_000473705.1 | isoprenyl transferase | - |
| FORC45_RS06245 (FORC45_1155) | - | 1232304..1233086 (+) | 783 | WP_000868413.1 | phosphatidate cytidylyltransferase | - |
| FORC45_RS06250 (FORC45_1156) | rseP | 1233298..1234584 (+) | 1287 | WP_000121122.1 | RIP metalloprotease RseP | - |
| FORC45_RS06255 (FORC45_1157) | - | 1234604..1236307 (+) | 1704 | WP_000814108.1 | proline--tRNA ligase | - |
| FORC45_RS06260 (FORC45_1158) | - | 1236571..1240881 (+) | 4311 | WP_001820550.1 | DNA polymerase III subunit alpha | - |
| FORC45_RS06270 (FORC45_1159) | rimP | 1241171..1241638 (+) | 468 | WP_000036631.1 | ribosome maturation factor RimP | - |
| FORC45_RS06275 (FORC45_1160) | nusA | 1241659..1242834 (+) | 1176 | WP_000097457.1 | transcription termination factor NusA | - |
| FORC45_RS06280 (FORC45_1161) | rnpM | 1242855..1243139 (+) | 285 | WP_000727423.1 | RNase P modulator RnpM | - |
| FORC45_RS06285 (FORC45_1162) | - | 1243136..1243453 (+) | 318 | WP_000020853.1 | YlxQ family RNA-binding protein | - |
| FORC45_RS06290 (FORC45_1163) | infB | 1243458..1245575 (+) | 2118 | WP_000043632.1 | translation initiation factor IF-2 | - |
| FORC45_RS06295 (FORC45_1164) | rbfA | 1245961..1246311 (+) | 351 | WP_000097322.1 | 30S ribosome-binding factor RbfA | - |
| FORC45_RS06300 (FORC45_1165) | truB | 1246481..1247398 (+) | 918 | WP_000282305.1 | tRNA pseudouridine(55) synthase TruB | - |
| FORC45_RS06305 (FORC45_1166) | ribF | 1247413..1248384 (+) | 972 | WP_000864192.1 | riboflavin biosynthesis protein RibF | - |
Sequence
Protein
Download Length: 290 a.a. Molecular weight: 33564.99 Da Isoelectric Point: 9.5094
>NTDB_id=195783 FORC45_RS06175 WP_000593192.1 1218844..1219716(+) (dprA) [Staphylococcus aureus strain FORC_045]
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
MIKLFLLKLYWAHFSTKQIHQFLMAYPNVIKEEGRKKDSYLCEWVNREENVHLLRKYYAFIKLDHNDIIKELQKLKVSYI
TYMDSEYPVLLKEIYQFPLLLFYKGNIKLINNMHHLAVVGARDSTSYTQQSLEFLLSNDKSKYLTIVSGLAQGADAMAHQ
IALKYNLPTIAVLAFGHQTHYPKSTLALRNKIEEKGLVISEYPPHTPIAKYRFPERNRIISGLSKGVLITEAKEQSGSHI
TIDFALEQNRNVYVLPGSMFNPMTKGNLLRIQEGAKVVLNANDIFEDYYI
Nucleotide
Download Length: 873 bp
>NTDB_id=195783 FORC45_RS06175 WP_000593192.1 1218844..1219716(+) (dprA) [Staphylococcus aureus strain FORC_045]
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA
TTGATTAAACTATTTTTGCTTAAGTTATACTGGGCACACTTTTCGACTAAACAAATTCATCAATTTTTAATGGCATATCC
TAATGTAATTAAAGAGGAGGGAAGAAAAAAAGATAGTTATTTATGTGAATGGGTGAATAGGGAAGAAAATGTTCATTTAT
TACGTAAATACTATGCTTTTATAAAACTTGATCATAACGATATTATTAAAGAACTGCAGAAATTAAAAGTAAGTTACATT
ACATATATGGATTCTGAATACCCAGTGCTATTAAAAGAAATATATCAATTTCCATTACTTCTTTTCTATAAAGGGAACAT
CAAATTAATAAATAATATGCATCATTTGGCAGTAGTAGGTGCAAGAGATTCTACAAGTTATACCCAACAGTCTTTAGAAT
TTTTATTATCAAATGATAAAAGCAAATATTTAACAATTGTTTCCGGCCTTGCTCAAGGAGCTGATGCAATGGCACATCAA
ATAGCTTTAAAATACAATCTCCCTACAATTGCAGTTTTAGCCTTTGGCCATCAAACACATTATCCCAAAAGTACATTAGC
ATTAAGAAATAAAATAGAAGAAAAAGGTTTAGTTATATCCGAATATCCACCACATACACCAATTGCTAAATATAGATTTC
CTGAGCGCAATAGAATTATCAGCGGTTTGTCAAAAGGGGTTTTAATTACTGAGGCTAAGGAACAAAGTGGCAGTCACATC
ACGATAGATTTTGCATTAGAGCAAAATAGAAATGTTTATGTTTTACCTGGATCTATGTTTAATCCTATGACAAAAGGTAA
TTTATTACGTATCCAAGAAGGTGCTAAGGTAGTATTAAACGCTAATGATATATTTGAAGACTACTATATTTAA
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| dprA | Staphylococcus aureus MW2 |
100 |
100 |
1 |
| dprA | Staphylococcus aureus N315 |
99.655 |
100 |
0.997 |