Detailed information NTG0195566

Bioinformatically predicted

Overview

• Name: comA
• Type: Machinery gene
• Locus tag: BG483_RS10785
• Genome accession: NZ_CP017099
• Coordinates: 2251250..2253475 (-)
• Length: 741 a.a.
• NCBI ID: WP_023100928.1
• Uniprot ID: A0A509JMW0
• Organism: Pseudomonas aeruginosa strain DN1
• Function: ssDNA transport through the inner membrane (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2246250..2258475

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
BG483_RS10750 (BG483_10315)	murB	2246640..2247659 (-)	1020	WP_021265002.1	UDP-N-acetylmuramate dehydrogenase	-
BG483_RS10755 (BG483_10320)	-	2247656..2248120 (-)	465	WP_003106924.1	low molecular weight protein-tyrosine-phosphatase	-
BG483_RS10760 (BG483_10325)	kdsB	2248120..2248884 (-)	765	WP_003091155.1	3-deoxy-manno-octulosonate cytidylyltransferase	-
BG483_RS10765 (BG483_10330)	-	2248884..2249069 (-)	186	WP_003091157.1	Trm112 family protein	-
BG483_RS10770 (BG483_10335)	lpxK	2249107..2250105 (-)	999	WP_003130692.1	tetraacyldisaccharide 4'-kinase	-
BG483_RS10775 (BG483_10340)	-	2250105..2250545 (-)	441	WP_003091161.1	ExbD/TolR family protein	-
BG483_RS10780 (BG483_10345)	exbB	2250542..2251177 (-)	636	WP_003091163.1	MotA/TolQ/ExbB proton channel family protein	Machinery gene
BG483_RS10785 (BG483_10350)	comA	2251250..2253475 (-)	2226	WP_023100928.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
BG483_RS10790 (BG483_10355)	-	2253606..2254139 (+)	534	WP_003091165.1	DUF2062 domain-containing protein	-
BG483_RS10795 (BG483_10360)	-	2254215..2255459 (-)	1245	WP_003105198.1	lipoprotein-releasing ABC transporter permease subunit	-
BG483_RS10800 (BG483_10365)	lolD	2255529..2256212 (-)	684	WP_003091168.1	lipoprotein-releasing ABC transporter ATP-binding protein LolD	-
BG483_RS10805 (BG483_10370)	-	2256205..2257455 (-)	1251	WP_015502671.1	lipoprotein-releasing ABC transporter permease subunit	-
BG483_RS10810 (BG483_10375)	-	2257558..2258157 (+)	600	WP_003091172.1	PilZ domain-containing protein	-
BG483_RS10815 (BG483_10380)	-	2258167..2258475 (+)	309	WP_021265003.1	hypothetical protein	-

Sequence

Protein

• Length: 741 a.a.
• Molecular weight: 79964.54 Da
• Isoelectric Point: 10.5155

>NTDB_id=195566 BG483_RS10785 WP_023100928.1 2251250..2253475(-) (comA) [Pseudomonas aeruginosa strain DN1]
MRLGLPALAAGLLALRFLAELPSVGWLLGMAAAGLLLLFGRLYWLGLFLLGFAWACGSAQVALDGRLAAELDGRTLWLEG
RVVDLPASGEGVTRFRLEEVSAARGVLLPERLRLSWRGAPPLMGGERWRLAVTLKRPRGLVNAAGFDYEAWLLAQRVGAV
GTVKAGQRLQPASGLDAWRDAWRQRLLAVDAQGRGAALAALVLGDGSGLSAAEWRMFQDTGTVHLMVISGSHISLLAGML
YGLVAALHRLGCWPRRLPWLPCACALGLLGAWSYGLMAGFEVPVRRACLMVSLALVWRLRFRHLGLLTPLLGTLVLVLLV
EPLASLQAGFWLSFLAVALLLWLFAGRLGRWRWWAAWGRAQWGMALGLAMPLLALGLPLSLSGAPANLLAVPWIELLVVP
PALAGSLLLWVPGLGEGLLRAAGVSLDLLFRALGLLAGLAEAWQPPAAAAWSVALGMLGALCWLAPAGLPLRALGAALLL
PALLPSSPPVEWGRAEVRVLDVGQGLAVLVRTREHALLYDSGARQGAFDMGERVVVPVLRSLDLRRLDGLLLSHADNDHA
GGAPTVASRFPPGWLVSGEPARLPSPLFADSCDERRWSWDGVVFEQWAWAQAGDSNDRSCVLRVEADGEVLLLTGDISRA
AEHAWLARQADPRVDWLLAPHHGSRSSSGVAFVLRTRPRHVLVSRGWRNAFGHPHGEVMERYARVAAQVHDTARDGALTF
LLGSRGGARRERDSAHFWREK

Nucleotide

• Length: 2226 bp

>NTDB_id=195566 BG483_RS10785 WP_023100928.1 2251250..2253475(-) (comA) [Pseudomonas aeruginosa strain DN1]
ATGCGCCTGGGATTGCCAGCTCTCGCCGCGGGGCTGCTGGCCCTGCGCTTCCTGGCGGAATTGCCGTCGGTCGGCTGGCT
GCTGGGCATGGCCGCCGCCGGACTGTTGCTGCTGTTCGGCCGGCTGTACTGGCTGGGGTTGTTCCTGCTCGGGTTCGCCT
GGGCCTGCGGCTCGGCGCAAGTCGCCCTGGACGGACGCCTGGCCGCCGAGCTGGATGGTCGCACCCTTTGGCTGGAGGGG
CGTGTGGTCGATCTGCCGGCGAGCGGCGAGGGCGTCACGCGCTTCCGGCTGGAGGAGGTCAGCGCTGCGCGGGGCGTGCT
TCTTCCCGAGCGTCTGCGCCTGAGCTGGCGCGGCGCGCCGCCGCTGATGGGCGGCGAACGCTGGCGCCTGGCGGTGACCC
TGAAACGCCCCCGCGGCCTGGTGAACGCGGCGGGTTTCGACTACGAGGCCTGGTTGTTGGCGCAGCGGGTCGGTGCTGTG
GGCACGGTGAAGGCGGGCCAACGCCTGCAGCCGGCCAGCGGCCTGGATGCCTGGCGCGATGCCTGGCGCCAGCGCCTGCT
GGCGGTCGACGCACAGGGGCGCGGCGCCGCCCTGGCGGCGCTGGTGCTGGGGGATGGCTCGGGATTGAGCGCGGCCGAGT
GGCGAATGTTCCAGGACACCGGCACCGTGCATCTGATGGTCATCTCCGGTTCGCATATCTCGTTGCTGGCAGGGATGCTC
TATGGCCTGGTGGCGGCCTTGCATCGCCTGGGCTGCTGGCCGCGGCGCTTGCCCTGGCTGCCCTGTGCCTGCGCCCTGGG
TTTGCTTGGTGCCTGGAGCTACGGGTTGATGGCGGGTTTCGAGGTCCCGGTGCGGCGTGCTTGCCTGATGGTCAGCCTGG
CGCTGGTCTGGCGCCTGCGTTTCCGCCACCTGGGCTTGCTGACCCCGCTGCTGGGAACGCTGGTGCTGGTCTTGCTGGTC
GAGCCGCTGGCCAGCCTGCAGGCGGGGTTCTGGCTGTCGTTCCTGGCGGTTGCCCTGCTGCTCTGGCTGTTCGCCGGGCG
CCTTGGGCGCTGGCGCTGGTGGGCGGCCTGGGGGCGGGCGCAGTGGGGGATGGCGCTGGGGCTGGCGATGCCGCTGCTGG
CGCTGGGCCTGCCGTTGAGCCTGAGCGGAGCGCCGGCCAACCTGCTGGCGGTGCCTTGGATCGAACTGCTGGTAGTGCCC
CCGGCCCTGGCTGGGAGCCTGCTGCTATGGGTGCCCGGGCTGGGCGAGGGGCTGCTTCGCGCCGCTGGCGTTTCGCTGGA
CCTGCTGTTTCGTGCACTTGGCCTGCTGGCGGGCCTGGCCGAGGCGTGGCAGCCACCCGCCGCAGCGGCCTGGAGCGTAG
CGCTGGGCATGCTCGGCGCGCTCTGCTGGCTGGCGCCGGCTGGCTTGCCGTTGCGTGCCCTCGGTGCCGCGTTGCTACTG
CCGGCGTTGTTGCCGTCATCGCCGCCTGTCGAATGGGGGCGGGCGGAAGTGCGGGTGCTGGACGTCGGCCAGGGGCTGGC
CGTGCTGGTGCGTACCCGGGAGCATGCCTTGCTCTATGACAGCGGTGCGCGGCAGGGGGCGTTCGACATGGGCGAGCGGG
TGGTGGTGCCGGTGCTGCGCAGCCTGGACCTGCGGCGCCTGGACGGCCTGTTGCTGAGCCATGCCGACAACGACCATGCA
GGCGGTGCTCCTACGGTCGCTTCCCGATTCCCGCCGGGTTGGCTGGTCAGCGGCGAACCCGCGCGCCTGCCTTCGCCGTT
GTTCGCGGACAGCTGCGACGAGCGGCGCTGGTCCTGGGATGGCGTGGTTTTCGAACAGTGGGCATGGGCGCAGGCCGGCG
ACAGCAACGACCGCTCCTGCGTGCTGAGGGTCGAGGCCGATGGCGAAGTCCTGCTGCTGACCGGGGACATCTCGCGTGCG
GCCGAGCATGCCTGGCTGGCGCGACAGGCCGATCCGCGGGTCGACTGGTTGCTGGCGCCGCATCACGGCAGCCGCAGCTC
CTCCGGAGTCGCCTTCGTGTTGCGTACGCGGCCTCGCCATGTGCTGGTCTCGCGAGGTTGGCGCAACGCCTTCGGCCATC
CCCATGGCGAAGTGATGGAACGTTACGCGAGGGTCGCCGCGCAGGTCCACGACACGGCACGCGACGGTGCCCTGACGTTT
CTCCTCGGAAGCCGTGGCGGCGCACGCCGGGAGCGTGATTCGGCGCACTTCTGGCGGGAAAAATGA

Domains

Predicted by InterproScan.

• Domain of unknown function (DUF4131) (DUF4131) (21-168)

• Metallo-beta-lactamase superfamily (Lactamase_B) (501-666)

• Competence protein (Competence) (201-464)

3D structure

• AlphaFold DB: A0A509JMW0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA	Pseudomonas stutzeri DSM 10701	59.223	97.301	0.576
comA	Ralstonia pseudosolanacearum GMI1000	35.742	100	0.367