Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   A2U18_RS08465 Genome accession   NZ_CP017091
Coordinates   1684904..1685590 (-) Length   228 a.a.
NCBI ID   WP_001825349.1    Uniprot ID   -
Organism   Staphylococcus aureus strain ISU926 isolate ST398     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1679904..1690590
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A2U18_RS08445 (A2U18_08180) rpsT 1680818..1681069 (+) 252 WP_001274017.1 30S ribosomal protein S20 -
  A2U18_RS08450 (A2U18_08185) holA 1681114..1682088 (-) 975 WP_001282570.1 DNA polymerase III subunit delta -
  A2U18_RS08455 (A2U18_08190) comEC 1682145..1684346 (-) 2202 WP_001807826.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  A2U18_RS08460 (A2U18_08195) - 1684351..1684812 (-) 462 WP_000439690.1 ComE operon protein 2 -
  A2U18_RS08465 (A2U18_08200) comEA 1684904..1685590 (-) 687 WP_001825349.1 ComEA family DNA-binding protein Machinery gene
  A2U18_RS08470 (A2U18_08205) - 1685630..1686346 (-) 717 WP_000084838.1 class I SAM-dependent DNA methyltransferase -
  A2U18_RS08475 (A2U18_08210) rsfS 1686349..1686702 (-) 354 WP_001088020.1 ribosome silencing factor -
  A2U18_RS08480 (A2U18_08215) yqeK 1686703..1687287 (-) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  A2U18_RS08485 (A2U18_08220) nadD 1687277..1687846 (-) 570 WP_000725164.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  A2U18_RS08490 (A2U18_08225) yhbY 1687849..1688139 (-) 291 WP_000955234.1 ribosome assembly RNA-binding protein YhbY -
  A2U18_RS08495 (A2U18_08230) aroE 1688143..1688949 (-) 807 WP_000666746.1 shikimate dehydrogenase -
  A2U18_RS08500 (A2U18_08235) yqeH 1688963..1690063 (-) 1101 WP_001280151.1 ribosome biogenesis GTPase YqeH -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25783.41 Da        Isoelectric Point: 9.3305

>NTDB_id=195494 A2U18_RS08465 WP_001825349.1 1684904..1685590(-) (comEA) [Staphylococcus aureus strain ISU926 isolate ST398]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRDFENKDTALKQSTSENSSLSKLEDVQVKDGDDSK
NKGPVYVDIKGAVKHPNVYKMTSKDRVVDLLDKAQLLDDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQFGANSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTT

Nucleotide


Download         Length: 687 bp        

>NTDB_id=195494 A2U18_RS08465 WP_001825349.1 1684904..1685590(-) (comEA) [Staphylococcus aureus strain ISU926 isolate ST398]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAGATTTTGAAAATAAAGATACTG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAATTAGAAGATGTCCAGGTCAAAGATGGAGATGATTCCAAA
AATAAAGGTCCTGTATATGTCGATATAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTAGATGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATTCCTCATAAAGGACAAAAGAATGTTGAACCACAATTTGGAGCAAACAGTGTGCACGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACGGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGACATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

96.476

99.561

0.961
  comEA Staphylococcus aureus N315

96.476

99.561

0.961

Multiple sequence alignment