Detailed information NTG0195437

Bioinformatically predicted

Overview

• Name: coiA
• Type: Machinery gene
• Locus tag: A2V17_RS05150
• Genome accession: NZ_CP017090
• Coordinates: 1011770..1012756 (+)
• Length: 328 a.a.
• NCBI ID: WP_000959282.1
• Uniprot ID: A0A7U7EXT8
• Organism: Staphylococcus aureus strain ISU935 isolate ST5
• Function: require for natural transformation (predicted from homology) Unclear

Genomic Context

Location: 1006770..1017756

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A2V17_RS05125 (A2V17_05010)	opp4B	1006984..1007946 (+)	963	WP_000915997.1	oligopeptide ABC transporter permease	-
A2V17_RS05130 (A2V17_05015)	opp4C	1007958..1008839 (+)	882	WP_001180280.1	oligopeptide ABC transporter permease	-
A2V17_RS05135 (A2V17_05020)	trpS	1008881..1009870 (-)	990	WP_000448934.1	tryptophan--tRNA ligase	-
A2V17_RS05140 (A2V17_05025)	spxA	1010164..1010559 (+)	396	WP_000258003.1	transcriptional regulator SpxA	-
A2V17_RS05145 (A2V17_05030)	mecA	1010930..1011649 (+)	720	WP_001217728.1	adaptor protein MecA	-
A2V17_RS05150 (A2V17_05035)	coiA	1011770..1012756 (+)	987	WP_000959282.1	competence protein CoiA	Machinery gene
A2V17_RS05155 (A2V17_05040)	pepF	1012804..1014612 (+)	1809	WP_000082725.1	oligoendopeptidase F	-
A2V17_RS05160 (A2V17_05045)	yjbH	1015072..1015878 (-)	807	WP_000896697.1	protease adaptor protein YjbH	-
A2V17_RS05165 (A2V17_05050)	-	1015901..1016266 (-)	366	WP_000214070.1	truncated hemoglobin YjbI	-
A2V17_RS05170 (A2V17_05055)	-	1016370..1016963 (-)	594	WP_000224619.1	CYTH domain-containing protein	-
A2V17_RS05175 (A2V17_05060)	-	1017149..1017496 (+)	348	WP_001242103.1	hypothetical protein	-

Sequence

Protein

• Length: 328 a.a.
• Molecular weight: 38878.55 Da
• Isoelectric Point: 9.5714

>NTDB_id=195437 A2V17_RS05150 WP_000959282.1 1011770..1012756(+) (coiA) [Staphylococcus aureus strain ISU935 isolate ST5]
MLVALNEEKERVLATTALRKTQYFCPVCGKQVILKRGLKVISHFAHKHLAEQKCFNNETIKHYKSKLILAQMIQQQGCKV
EIEPFLKEIKQIPDILINNKYVIELQYSPIPYKQILQRTEGLKKMGYKVSWLLNDVDYCHNKVKFNHFHSLFINPITRKL
HTFNLEKKQIMMFQQIQYLGGHKYVAEKRNAKIIELFNEAPCDYHAVYKLSKFAINQYIKYCRWQNSVLEPTLSAMYQLQ
LTDQEVVYNYGYIFPEQIYIENHPIEWQLQVDLWLKNGKSKLVNDNLNYFKLKKFIVALESKTAIIEKLINNYLNICSDR
GNDVQILF

Nucleotide

• Length: 987 bp

>NTDB_id=195437 A2V17_RS05150 WP_000959282.1 1011770..1012756(+) (coiA) [Staphylococcus aureus strain ISU935 isolate ST5]
ATGTTAGTAGCTTTAAATGAAGAAAAGGAACGTGTGTTAGCAACTACTGCATTGAGAAAGACACAATATTTTTGTCCTGT
GTGTGGCAAGCAAGTTATTTTAAAGCGTGGGCTCAAAGTAATTAGTCATTTTGCACATAAACATTTAGCGGAACAAAAAT
GTTTTAATAATGAAACGATTAAACATTATAAAAGTAAATTGATTTTAGCACAGATGATACAGCAACAAGGATGTAAAGTA
GAGATAGAGCCATTTTTAAAAGAAATAAAACAAATTCCGGATATTTTGATTAATAATAAATATGTTATTGAGCTACAGTA
TTCGCCAATTCCTTATAAACAGATTCTTCAACGAACGGAAGGTTTAAAGAAAATGGGATATAAAGTAAGTTGGTTATTAA
ATGATGTTGATTATTGTCATAATAAAGTGAAGTTCAATCATTTTCATAGTTTGTTTATTAATCCAATCACTCGAAAACTT
CATACGTTCAATTTAGAGAAAAAACAAATAATGATGTTTCAACAAATACAATATTTAGGCGGGCACAAATATGTCGCTGA
AAAAAGGAATGCCAAAATTATTGAGTTGTTTAATGAGGCGCCTTGTGATTATCATGCTGTTTATAAATTATCAAAGTTCG
CAATTAATCAATATATCAAATATTGTCGCTGGCAAAATTCTGTTTTAGAACCCACTTTAAGTGCAATGTATCAATTACAG
TTAACTGATCAAGAAGTAGTGTACAATTATGGTTATATTTTTCCAGAGCAAATTTATATTGAAAATCATCCAATTGAGTG
GCAATTACAAGTTGATTTATGGTTAAAGAATGGAAAAAGCAAATTAGTAAATGACAATCTTAATTATTTTAAACTGAAAA
AATTTATTGTTGCTCTAGAAAGTAAAACAGCAATTATAGAAAAACTTATTAACAATTATTTAAATATTTGTTCAGATAGA
GGTAATGACGTGCAAATTTTGTTCTAA

Domains

Predicted by InterproScan.

• Competence protein CoiA-like family (CoiA_nuc) (6-308)

3D structure

• AlphaFold DB: A0A7U7EXT8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
coiA	Staphylococcus aureus N315	100	100	1
coiA	Staphylococcus aureus MW2	97.561	100	0.976