Detailed information NTG0195422

Bioinformatically predicted

Overview

• Name: htrA
• Type: Regulator
• Locus tag: A7J08_RS10285
• Genome accession: NZ_CP017088
• Coordinates: 2060791..2061987 (+)
• Length: 398 a.a.
• NCBI ID: WP_053867303.1
• Uniprot ID: -
• Organism: Streptococcus suis strain SRD478
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 2055791..2066987

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7J08_RS10245 (A7J08_09990)	-	2056089..2057339 (+)	1251	WP_053867306.1	replication initiation factor domain-containing protein	-
A7J08_RS10250 (A7J08_09995)	-	2057402..2057740 (+)	339	WP_029186211.1	DUF771 domain-containing protein	-
A7J08_RS10255 (A7J08_10000)	-	2057803..2058924 (+)	1122	WP_053867305.1	site-specific integrase	-
A7J08_RS10275 (A7J08_10020)	-	2059430..2060113 (-)	684	WP_053867304.1	YoaK family protein	-
A7J08_RS10280 (A7J08_10025)	rlmH	2060138..2060617 (-)	480	WP_004194528.1	23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH	-
A7J08_RS10285 (A7J08_10030)	htrA	2060791..2061987 (+)	1197	WP_053867303.1	trypsin-like peptidase domain-containing protein	Regulator
A7J08_RS10290 (A7J08_10035)	spo0J	2062048..2062812 (+)	765	WP_024400054.1	ParB/RepB/Spo0J family partition protein	Regulator

Sequence

Protein

• Length: 398 a.a.
• Molecular weight: 41804.80 Da
• Isoelectric Point: 4.5940

>NTDB_id=195422 A7J08_RS10285 WP_053867303.1 2060791..2061987(+) (htrA) [Streptococcus suis strain SRD478]
MERIPYMKKYLKFAILFVIGFFGGLIGALSASFFQPQVQQANSAITSVSNVQYNNETSTTKAVEKVQNAVVSVINYQKSA
NNSLGAIFGNIESSDELAVAGEGSGVIYKKDGQYAYIVTNTHVINNAEKIDILLASGEKISGELVGSDTYSDIAVIKISA
DKVTAVAEFADSDTIKVGETAIAIGSPLGSIYANTVTQGIISSLSRTVTSQSKDGQTISTNAIQTDTAINPGNSGGPLIN
TQGQVIGITSSKITSSSANSSGVAVEGLGFAIPANDAVAIINQLEKTGQVSRPALGVHMVNLTTLSTSQLEKAGLSNTEL
TSGVVIVSTQSGLPADGKLETFDVITEIDGEAIQNKSDLQSALYKHQIGDTITVTYYRNNQKQTVDIKLTHSTEELSE

Nucleotide

• Length: 1197 bp

>NTDB_id=195422 A7J08_RS10285 WP_053867303.1 2060791..2061987(+) (htrA) [Streptococcus suis strain SRD478]
ATGGAAAGGATTCCTTATATGAAAAAATATTTGAAATTTGCGATTTTATTTGTAATTGGATTTTTTGGGGGTCTTATCGG
GGCCTTATCAGCCTCTTTCTTCCAGCCACAGGTTCAACAAGCAAATTCTGCTATCACTAGTGTCAGCAATGTTCAATATA
ATAATGAAACTTCCACCACAAAAGCTGTAGAGAAAGTACAAAATGCTGTTGTGTCTGTTATTAATTACCAAAAGTCAGCT
AACAATAGTCTTGGTGCTATCTTTGGAAATATTGAATCATCTGACGAACTAGCCGTTGCTGGGGAGGGATCTGGTGTTAT
CTACAAAAAAGATGGTCAATATGCCTATATTGTGACAAATACGCATGTTATTAATAACGCAGAAAAGATTGATATCCTTT
TAGCATCTGGAGAAAAAATTAGCGGTGAACTTGTTGGTTCCGATACATATTCTGATATAGCTGTTATAAAAATATCAGCA
GATAAAGTCACTGCTGTTGCTGAATTTGCTGATTCCGATACAATTAAAGTTGGAGAAACTGCTATCGCAATTGGTAGTCC
TCTAGGCAGCATCTACGCCAATACAGTCACCCAGGGTATTATTTCTAGCTTAAGTCGGACAGTTACTTCACAATCAAAAG
ATGGACAAACAATCTCAACCAACGCTATTCAAACTGATACAGCTATCAACCCTGGAAACTCTGGCGGACCGTTAATCAAT
ACCCAAGGACAAGTGATAGGCATTACCTCTAGCAAAATTACCTCAAGTTCTGCAAATAGCTCAGGCGTGGCTGTAGAAGG
GTTGGGATTTGCTATTCCTGCAAATGATGCCGTAGCTATTATCAATCAGCTTGAAAAAACTGGACAAGTTAGCCGACCTG
CTCTTGGAGTTCATATGGTTAACTTGACGACCTTGTCAACTAGTCAATTAGAAAAAGCTGGATTATCAAATACGGAATTA
ACATCCGGTGTCGTAATTGTCTCTACACAAAGTGGACTACCTGCAGATGGAAAATTAGAAACTTTTGATGTTATTACTGA
GATTGACGGAGAAGCTATTCAAAATAAGAGTGACCTCCAGAGCGCTCTCTACAAACATCAAATTGGAGATACAATCACTG
TAACTTATTACCGCAATAATCAGAAACAAACTGTTGACATTAAGTTGACACATTCTACAGAAGAACTTAGCGAATAA

Domains

Predicted by InterproScan.

• PDZ domain (PDZ_2) (293-389)

• Trypsin-like peptidase domain (Trypsin_2) (103-248)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
htrA	Streptococcus mutans UA159	59.446	99.749	0.593
htrA	Streptococcus gordonii str. Challis substr. CH1	59.494	99.246	0.59
htrA	Streptococcus pneumoniae D39	57.252	98.744	0.565
htrA	Streptococcus pneumoniae TIGR4	57.252	98.744	0.565
htrA	Streptococcus mitis NCTC 12261	57.252	98.744	0.565
htrA	Streptococcus pneumoniae R6	57.252	98.744	0.565
htrA	Streptococcus pneumoniae Rx1	57.252	98.744	0.565