Detailed information    

insolico Bioinformatically predicted

Overview

Name   covR   Type   Regulator
Locus tag   A7J08_RS08055 Genome accession   NZ_CP017088
Coordinates   1609460..1610149 (-) Length   229 a.a.
NCBI ID   WP_012027645.1    Uniprot ID   -
Organism   Streptococcus suis strain SRD478     
Function   repress comR expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1604460..1615149
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS08030 (A7J08_07810) - 1604935..1605648 (-) 714 WP_053866693.1 NADPH-dependent oxidoreductase -
  A7J08_RS08035 (A7J08_07815) dnaI 1605645..1606544 (-) 900 WP_053866692.1 primosomal protein DnaI -
  A7J08_RS08040 (A7J08_07820) - 1606544..1607695 (-) 1152 WP_053866691.1 replication initiation/membrane attachment protein -
  A7J08_RS08045 (A7J08_07825) nrdR 1607682..1608173 (-) 492 WP_002938341.1 transcriptional regulator NrdR -
  A7J08_RS08050 (A7J08_07830) - 1608245..1609375 (-) 1131 WP_012027644.1 AI-2E family transporter -
  A7J08_RS08055 (A7J08_07835) covR 1609460..1610149 (-) 690 WP_012027645.1 winged helix-turn-helix domain-containing protein Regulator
  A7J08_RS08060 (A7J08_07840) gndA 1610231..1611658 (-) 1428 WP_024394979.1 NADP-dependent phosphogluconate dehydrogenase -
  A7J08_RS08065 (A7J08_07845) - 1611755..1612294 (-) 540 WP_053866690.1 DUF177 domain-containing protein -
  A7J08_RS08070 (A7J08_07850) trxB 1612304..1613221 (-) 918 WP_002942687.1 thioredoxin-disulfide reductase -
  A7J08_RS08075 (A7J08_07855) - 1613235..1613459 (-) 225 WP_014638521.1 DUF4059 family protein -
  A7J08_RS08080 (A7J08_07860) - 1613477..1614820 (-) 1344 WP_053866689.1 DEAD/DEAH box helicase -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 26255.14 Da        Isoelectric Point: 5.3968

>NTDB_id=195413 A7J08_RS08055 WP_012027645.1 1609460..1610149(-) (covR) [Streptococcus suis strain SRD478]
MAKKILIAGKERNLSHFVSMELQKKDYLVDYASTGKEAMSLAHETDFDLILMSFQLSDMSSKELATELLAIKPATVMIVV
VEPTEVSQYGEEVLSYAVSYVVKPFVISDLVEQISAIFRGRDFIDNNCKQVHMHAAYRDLKVDFQNRTVTRGDELINLTR
REYDLLATLMNSPEPVSREQLLERVWKYEAASETNVVDVYIRYLRGKLDLPHQDSYIKTVRGVGYAMRD

Nucleotide


Download         Length: 690 bp        

>NTDB_id=195413 A7J08_RS08055 WP_012027645.1 1609460..1610149(-) (covR) [Streptococcus suis strain SRD478]
ATGGCTAAGAAAATTTTGATTGCTGGTAAAGAACGCAATCTCTCGCATTTTGTTTCCATGGAATTGCAGAAAAAAGACTA
TCTTGTTGATTATGCATCGACAGGGAAAGAGGCTATGTCCTTGGCACATGAAACGGATTTTGACTTGATTCTGATGAGTT
TTCAGCTTTCAGACATGTCCAGTAAGGAATTGGCCACGGAACTGTTAGCGATAAAACCAGCCACGGTCATGATTGTGGTA
GTTGAGCCGACAGAAGTTAGTCAATATGGGGAAGAAGTCCTCTCTTATGCTGTTTCCTACGTAGTGAAGCCCTTCGTCAT
CAGTGATTTAGTGGAGCAAATCTCTGCGATTTTTCGTGGTCGTGATTTTATTGACAATAACTGTAAACAGGTTCACATGC
ATGCGGCCTATCGTGATTTGAAGGTTGATTTTCAAAATCGAACAGTGACTCGAGGTGATGAATTGATTAATTTGACCCGC
CGAGAGTATGATCTGTTGGCGACCTTAATGAATAGCCCAGAGCCTGTTAGTCGAGAACAACTTCTTGAGCGTGTTTGGAA
ATATGAAGCGGCTTCTGAGACCAATGTCGTCGATGTATATATTCGCTATCTACGTGGTAAACTGGATTTGCCACATCAAG
ATTCATATATTAAAACGGTTCGTGGTGTCGGCTATGCCATGCGCGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(155-227)

Response regulator receiver domain (Response_reg)

(5-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covR Streptococcus salivarius strain HSISS4

47.619

100

0.48
  covR Lactococcus lactis subsp. lactis strain DGCC12653

41.949

100

0.432

Multiple sequence alignment