Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpX   Type   Regulator
Locus tag   A7J08_RS05315 Genome accession   NZ_CP017088
Coordinates   1050452..1051678 (-) Length   408 a.a.
NCBI ID   WP_002934974.1    Uniprot ID   G7SE29
Organism   Streptococcus suis strain SRD478     
Function   require for competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1045452..1056678
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7J08_RS05290 (A7J08_05125) - 1045769..1047082 (-) 1314 WP_043024877.1 excalibur calcium-binding domain-containing protein -
  A7J08_RS05295 (A7J08_05130) - 1047217..1047399 (+) 183 WP_002934978.1 4-oxalocrotonate tautomerase -
  A7J08_RS05300 (A7J08_05135) lepA 1047448..1049280 (-) 1833 WP_044678415.1 translation elongation factor 4 -
  A7J08_RS05305 (A7J08_05140) ndk 1049376..1049788 (-) 413 Protein_976 nucleoside-diphosphate kinase -
  A7J08_RS05310 (A7J08_05145) yihA 1049811..1050398 (-) 588 WP_044678413.1 ribosome biogenesis GTP-binding protein YihA/YsxC -
  A7J08_RS05315 (A7J08_05150) clpX 1050452..1051678 (-) 1227 WP_002934974.1 ATP-dependent Clp protease ATP-binding subunit ClpX Regulator
  A7J08_RS05325 (A7J08_05160) - 1051876..1052388 (-) 513 WP_053866944.1 dihydrofolate reductase -
  A7J08_RS05330 (A7J08_05165) - 1052727..1053566 (-) 840 WP_053866945.1 thymidylate synthase -
  A7J08_RS05335 (A7J08_05170) - 1053618..1053920 (-) 303 WP_024406323.1 hypothetical protein -
  A7J08_RS05340 (A7J08_05175) - 1053932..1054210 (-) 279 WP_002934968.1 hypothetical protein -
  A7J08_RS05345 (A7J08_05180) - 1054335..1055294 (-) 960 WP_029179049.1 ROK family glucokinase -
  A7J08_RS05350 (A7J08_05185) - 1055386..1055721 (-) 336 WP_043024893.1 hypothetical protein -

Sequence

Protein


Download         Length: 408 a.a.        Molecular weight: 45318.84 Da        Isoelectric Point: 4.6382

>NTDB_id=195406 A7J08_RS05315 WP_002934974.1 1050452..1051678(-) (clpX) [Streptococcus suis strain SRD478]
MAVKHTHELIYCSFCGKNQEEVKKIIAGNNVFICNECVELAQEIIREELAEEVLTDLADTPKPQELLNILNNYVIGQDRA
KRALAVAVYNHYKRINFQDSRDENDVDLQKSNILMIGPTGSGKTFLAQTLAKSLNVPFAIADATALTEAGYVGEDVENIL
LKLLQAADFNIDRAERGIIYVDEIDKIAKKGENVSITRDVSGEGVQQALLKIIEGTVASVPPQGGRKHPNQEMIHVDTKN
ILFIVGGAFDGIEEIVKQRLGEKIIGFGHNNRAIDEKESYMQHIIADDIQKFGIIPELIGRLPVFAALDQLTTEDLVRIL
TEPKNALVKQYQTLLSYDDVELDFDEDALLAIAEKAIERKTGARGLRSIIEETMLDVMFEVPGQDNVKRVRVTKAAVDGK
EKPLLETA

Nucleotide


Download         Length: 1227 bp        

>NTDB_id=195406 A7J08_RS05315 WP_002934974.1 1050452..1051678(-) (clpX) [Streptococcus suis strain SRD478]
ATGGCTGTTAAGCATACACATGAGCTAATCTATTGCTCATTTTGCGGAAAAAATCAAGAAGAAGTTAAAAAAATTATCGC
TGGGAACAATGTCTTCATTTGTAATGAATGCGTGGAACTAGCACAGGAAATCATTCGTGAGGAACTGGCAGAAGAAGTTT
TGACAGACTTGGCCGATACGCCAAAGCCACAAGAATTACTCAATATCCTGAACAACTACGTCATCGGACAGGATCGTGCA
AAACGTGCTTTAGCAGTAGCCGTTTACAACCACTACAAACGTATCAATTTCCAGGATAGCCGTGATGAGAACGATGTTGA
TTTACAAAAATCAAATATCCTTATGATTGGCCCGACTGGTTCAGGAAAAACCTTCCTAGCTCAGACATTGGCTAAAAGTT
TGAATGTCCCGTTTGCTATTGCTGATGCGACCGCTCTTACTGAGGCGGGTTATGTTGGTGAAGACGTAGAAAATATCCTC
CTCAAACTTTTGCAGGCTGCAGACTTTAACATCGACCGTGCAGAAAGAGGAATTATCTATGTGGATGAAATTGATAAAAT
TGCCAAAAAAGGTGAAAATGTGTCCATTACCCGCGATGTATCTGGTGAAGGTGTTCAGCAAGCTCTCCTAAAAATTATCG
AGGGAACTGTGGCCAGCGTACCACCACAAGGCGGACGCAAACATCCAAACCAAGAAATGATTCACGTGGACACCAAAAAT
ATCCTGTTCATCGTTGGCGGTGCATTTGATGGTATCGAAGAAATCGTCAAACAGCGTCTCGGTGAAAAAATTATCGGTTT
TGGTCATAATAATCGTGCTATTGATGAAAAAGAATCATACATGCAACATATCATTGCAGACGATATTCAAAAATTCGGTA
TCATTCCAGAGTTGATTGGTCGCTTGCCTGTATTTGCAGCTTTGGACCAATTGACAACAGAGGATTTGGTACGTATTTTG
ACGGAACCGAAGAATGCTCTTGTAAAACAATACCAGACACTCTTGTCTTATGATGACGTGGAGCTTGACTTTGATGAGGA
CGCCTTGTTAGCAATTGCAGAAAAAGCAATTGAACGTAAGACTGGCGCTCGTGGACTTCGTTCCATCATTGAAGAAACGA
TGTTGGATGTCATGTTTGAGGTGCCAGGGCAAGATAACGTTAAACGTGTTCGTGTAACAAAAGCAGCAGTAGACGGTAAG
GAAAAGCCTTTACTAGAAACTGCTTAA

Domains

Predicted by InterproScan.

ClpX C4-type zinc finger (zf-C4_ClpX)

(11-47)

C-terminal, D2-small domain, of ClpB protein (ClpB_D2-small)

(311-389)

AAA domain (Cdc48 subfamily) (AAA_2)

(109-304)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SE29

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpX Streptococcus mutans UA159

83.13

100

0.833
  clpX Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.209

98.529

0.574

Multiple sequence alignment