Detailed information NTG0194677

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: S100141_RS19605
• Genome accession: NZ_CP021669
• Coordinates: 3709431..3710507 (+)
• Length: 358 a.a.
• NCBI ID: WP_003178277.1
• Uniprot ID: Q65PD4
• Organism: Bacillus licheniformis strain SRCM100141
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3704431..3715507

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
S100141_RS19590 (S100141_03962)	-	3704448..3705539 (+)	1092	WP_003178273.1	protein arginine kinase	-
S100141_RS19595 (S100141_03963)	clpC	3705536..3707968 (+)	2433	WP_003178275.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
S100141_RS19600 (S100141_03964)	radA/sms	3708048..3709427 (+)	1380	WP_003178276.1	DNA repair protein RadA	Machinery gene
S100141_RS19605 (S100141_03965)	disA	3709431..3710507 (+)	1077	WP_003178277.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
S100141_RS19610 (S100141_03966)	-	3710639..3711727 (+)	1089	WP_009330350.1	PIN/TRAM domain-containing protein	-
S100141_RS19615 (S100141_03967)	ispD	3711744..3712439 (+)	696	WP_009330349.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
S100141_RS19620 (S100141_03968)	ispF	3712432..3712908 (+)	477	WP_003178280.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
S100141_RS19625 (S100141_03969)	gltX	3712990..3714447 (+)	1458	WP_009330348.1	glutamate--tRNA ligase	-
S100141_RS19630 (S100141_03970)	cysE	3714749..3715399 (+)	651	WP_003178282.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 358 a.a.
• Molecular weight: 40582.27 Da
• Isoelectric Point: 6.5986

>NTDB_id=194677 S100141_RS19605 WP_003178277.1 3709431..3710507(+) (disA) [Bacillus licheniformis strain SRCM100141]
MDKDKKGAKQDLSEILQFVAPGTPLREGIENVLRAKTGGLIVVGFNDKVKEVVDGGFHINSSFSPAHLYELAKMDGAIIL
SDSGQKILYANTQLMPEATIPSSETGMRHRTAERVAKQTGCLIIAISERRNVITLYQENMKYILKDIGFILTKANQAIQT
LEKYKLILDHAISNLNALEFEELVTFGDVISVLHRYEMVLRIKNEINMYIKELGTEGHLIRLQVSELITDMEQEAALFVK
DYVKEKIKDPFVLLKQLQDMSSFELLDDAILLKLLGYSATTNMEEYVFPRGYRLLHKIPRLPMPIVENVVEAFGHLKLII
EADVKDLDEVEGIGAVRAQKIKKGLKRLQEKHYTDRQL

Nucleotide

• Length: 1077 bp

>NTDB_id=194677 S100141_RS19605 WP_003178277.1 3709431..3710507(+) (disA) [Bacillus licheniformis strain SRCM100141]
ATGGACAAAGACAAAAAAGGAGCGAAACAGGATCTTTCAGAAATATTGCAGTTTGTCGCCCCCGGCACGCCTCTTCGCGA
AGGAATCGAAAACGTCCTTCGGGCCAAAACAGGCGGATTAATCGTGGTCGGCTTCAACGATAAAGTGAAAGAAGTGGTTG
ACGGAGGGTTCCACATAAATTCTTCTTTCTCTCCGGCTCATCTGTACGAGCTGGCTAAAATGGACGGGGCGATCATTCTC
AGCGATTCAGGGCAAAAAATTCTATATGCCAATACACAGCTCATGCCTGAGGCGACGATTCCCTCCTCTGAGACGGGCAT
GAGACACAGAACAGCCGAGCGTGTGGCCAAGCAGACCGGCTGTCTGATCATCGCGATTTCTGAAAGACGGAATGTGATTA
CGCTCTATCAGGAAAATATGAAATATATACTCAAAGATATCGGCTTTATCTTAACAAAAGCCAATCAGGCGATTCAGACG
CTCGAAAAATACAAACTCATTTTGGACCATGCGATTTCCAATTTGAACGCGCTGGAATTTGAAGAGCTTGTTACATTTGG
GGATGTCATCTCCGTTCTGCATCGATATGAAATGGTGCTCAGAATCAAAAACGAAATTAATATGTATATTAAAGAGCTTG
GAACAGAAGGCCATCTCATCAGACTCCAGGTTAGCGAACTGATCACCGATATGGAGCAGGAAGCGGCGCTGTTCGTCAAA
GATTATGTGAAAGAAAAAATCAAAGACCCGTTTGTTCTGCTGAAACAGCTTCAGGATATGTCGAGTTTCGAATTGCTGGA
TGATGCGATTCTCCTTAAGCTTTTAGGCTATTCAGCAACTACGAACATGGAAGAATACGTTTTTCCGAGAGGCTACAGGC
TTCTCCACAAAATTCCCCGCCTCCCGATGCCGATCGTCGAAAATGTTGTCGAAGCATTCGGCCATTTAAAGCTCATTATC
GAAGCGGATGTAAAAGATTTGGATGAAGTGGAAGGAATTGGGGCTGTTCGTGCCCAAAAGATAAAGAAAGGGTTAAAGAG
ACTTCAGGAGAAACATTATACTGACAGGCAGCTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (27-139)

• DisA bacterial checkpoint controller linker region (DisA-linker) (144-282)

3D structure

• AlphaFold DB: Q65PD4

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	86.111	100	0.866