Detailed information NTG0193596

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: S101441_RS00600
• Genome accession: NZ_CP021507
• Coordinates: 110249..111331 (+)
• Length: 360 a.a.
• NCBI ID: WP_003225736.1
• Uniprot ID: P37573
• Organism: Bacillus subtilis subsp. subtilis strain SRCM101441
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 105249..116331

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
S101441_RS00585 (S101441_00117)	mcsB	105257..106348 (+)	1092	WP_003235007.1	protein arginine kinase	-
S101441_RS00590 (S101441_00118)	clpC	106345..108777 (+)	2433	WP_014475592.1	ATP-dependent protease ATP-binding subunit ClpC	Regulator
S101441_RS00595 (S101441_00119)	radA/sms	108869..110245 (+)	1377	WP_014475593.1	DNA repair protein RadA	Machinery gene
S101441_RS00600 (S101441_00120)	disA	110249..111331 (+)	1083	WP_003225736.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
S101441_RS00605 (S101441_00121)	yacL	111447..112547 (+)	1101	WP_003235014.1	PIN/TRAM domain-containing protein	-
S101441_RS00610 (S101441_00122)	ispD	112562..113260 (+)	699	WP_069837191.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-
S101441_RS00615 (S101441_00123)	ispF	113253..113729 (+)	477	WP_069837192.1	2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase	-
S101441_RS00620 (S101441_00124)	gltX	113820..115271 (+)	1452	WP_014478617.1	glutamate--tRNA ligase	-
S101441_RS00630 (S101441_00125)	cysE	115573..116226 (+)	654	WP_014478618.1	serine O-acetyltransferase	-

Sequence

Protein

• Length: 360 a.a.
• Molecular weight: 40734.29 Da
• Isoelectric Point: 5.7343

>NTDB_id=193596 S101441_RS00600 WP_003225736.1 110249..111331(+) (disA) [Bacillus subtilis subsp. subtilis strain SRCM101441]
MEKEKKGAKHELDLSSILQFVAPGTPLRAGMENVLRANTGGLIVVGYNDKVKEVVDGGFHINTAFSPAHLYELAKMDGAI
ILSDSGQKILYANTQLMPDATISSSETGMRHRTAERVAKQTGCLVIAISERRNVITLYQENMKYTLKDIGFILTKANQAI
QTLEKYKTILDKTINALNALEFEELVTFSDVLSVMHRYEMVLRIKNEINMYIKELGTEGHLIKLQVIELITDMEEEAALF
IKDYVKEKIKDPFVLLKELQDMSSYDLLDDSIVYKLLGYPASTNLDDYVLPRGYRLLNKIPRLPMPIVENVVEAFGVLPR
IIEASAEELDEVEGIGEVRAQKIKKGLKRLQEKHYLDRQL

Nucleotide

• Length: 1083 bp

>NTDB_id=193596 S101441_RS00600 WP_003225736.1 110249..111331(+) (disA) [Bacillus subtilis subsp. subtilis strain SRCM101441]
ATGGAAAAAGAGAAAAAAGGGGCGAAACACGAGTTAGACCTGTCATCTATATTGCAGTTTGTTGCTCCGGGTACACCGCT
CAGAGCGGGGATGGAAAACGTCTTGAGAGCAAATACAGGCGGTCTGATTGTTGTTGGATATAATGATAAAGTAAAAGAAG
TGGTGGACGGCGGCTTTCACATAAACACGGCTTTTTCTCCGGCGCATTTATATGAGTTGGCTAAAATGGATGGAGCGATC
ATTTTAAGTGATTCGGGTCAAAAGATCCTCTACGCGAATACTCAGCTGATGCCGGATGCCACAATTTCTTCATCAGAAAC
AGGAATGCGGCACAGAACTGCCGAAAGAGTAGCTAAGCAAACTGGCTGTCTTGTAATCGCTATTTCTGAAAGAAGAAATG
TCATAACGTTATATCAGGAAAACATGAAGTATACACTAAAAGACATAGGATTTATTTTAACCAAGGCGAACCAAGCCATT
CAAACACTTGAAAAGTATAAGACAATCCTCGATAAAACGATTAATGCACTGAACGCGTTAGAGTTTGAGGAACTTGTTAC
CTTCAGTGATGTCTTGTCTGTCATGCATCGTTATGAAATGGTACTGAGAATCAAAAACGAAATTAATATGTATATCAAAG
AGCTGGGGACAGAAGGGCATCTGATCAAACTGCAAGTCATTGAATTGATTACGGATATGGAAGAAGAGGCCGCTTTATTT
ATTAAGGACTATGTAAAAGAAAAGATTAAAGATCCGTTTGTCCTCTTGAAGGAGCTGCAGGATATGTCCAGTTATGATCT
GCTGGATGATTCCATTGTGTATAAGCTTCTCGGTTACCCTGCTTCTACTAATCTTGATGATTATGTATTGCCGAGAGGAT
ACAGGCTGTTAAATAAGATACCGCGTCTTCCGATGCCGATTGTTGAAAATGTTGTAGAAGCATTTGGAGTCCTGCCAAGG
ATTATTGAGGCGAGTGCAGAAGAATTAGATGAAGTAGAGGGAATCGGTGAAGTACGAGCCCAAAAAATCAAAAAAGGATT
AAAACGCCTGCAAGAGAAGCATTATTTAGACAGACAACTGTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (29-141)

• DisA bacterial checkpoint controller linker region (DisA-linker) (146-284)

3D structure

• AlphaFold DB: P37573

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	100	100	1