Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   BE845_RS10120 Genome accession   NZ_CP016874
Coordinates   2244957..2245616 (+) Length   219 a.a.
NCBI ID   WP_011216518.1    Uniprot ID   -
Organism   Legionella pneumophila subsp. pneumophila strain FFI329     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2239957..2250616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  BE845_RS10095 (BE845_10095) rplU 2240676..2240987 (+) 312 WP_011216522.1 50S ribosomal protein L21 -
  BE845_RS10100 (BE845_10100) rpmA 2241000..2241278 (+) 279 WP_010948350.1 50S ribosomal protein L27 -
  BE845_RS10105 (BE845_10105) cgtA 2241492..2242517 (+) 1026 WP_011216521.1 Obg family GTPase CgtA -
  BE845_RS10110 (BE845_10110) - 2242476..2243573 (-) 1098 WP_011216520.1 competence/damage-inducible protein A -
  BE845_RS10115 (BE845_10115) phhA 2244014..2244832 (+) 819 WP_011216519.1 phenylalanine 4-monooxygenase -
  BE845_RS10120 (BE845_10120) letA 2244957..2245616 (+) 660 WP_011216518.1 two-component system response regulator LetA Regulator
  BE845_RS10125 (BE845_10125) uvrC 2245628..2247484 (+) 1857 WP_011216517.1 excinuclease ABC subunit UvrC -
  BE845_RS10130 (BE845_10130) lcl 2247508..2248836 (-) 1329 WP_070322485.1 collagen-like adhesin Lcl -
  BE845_RS10135 (BE845_10135) - 2249004..2249663 (-) 660 WP_011216515.1 hypothetical protein -

Sequence

Protein


Download         Length: 219 a.a.        Molecular weight: 24556.49 Da        Isoelectric Point: 5.1572

>NTDB_id=193214 BE845_RS10120 WP_011216518.1 2244957..2245616(+) (letA) [Legionella pneumophila subsp. pneumophila strain FFI329]
MIKVLIVDDHALVRMGIRRLLEDMSDVDVVADAESGEQALAYVKTHSPDVVLLDMKMPGIDGWEVTRRLKKTNPNIKVIA
VTAICSDPLPTRVLQLGAMGYLTKESGAEEMAAAIRKVAKGEKYLSAEIAQKMAINSLQESQDSPFDLLSEREMQVMLMI
TSGMNVQDIADRLFLSSKTINGYRYRMFEKLGIKNDVELTYLAMKHRIIEHPNDLSQDD

Nucleotide


Download         Length: 660 bp        

>NTDB_id=193214 BE845_RS10120 WP_011216518.1 2244957..2245616(+) (letA) [Legionella pneumophila subsp. pneumophila strain FFI329]
TTGATTAAAGTATTAATTGTTGATGACCATGCATTGGTTAGAATGGGCATTCGACGATTGCTTGAAGATATGTCGGATGT
TGATGTGGTTGCAGATGCTGAAAGTGGTGAGCAGGCTTTGGCCTATGTGAAAACCCACTCCCCTGATGTCGTATTATTAG
ACATGAAAATGCCTGGGATAGATGGGTGGGAAGTGACACGTCGCTTAAAAAAAACAAACCCAAATATTAAAGTCATAGCA
GTTACAGCTATTTGCTCAGATCCTCTCCCTACTCGAGTATTGCAATTAGGTGCTATGGGATACCTTACTAAAGAGTCCGG
GGCTGAAGAAATGGCTGCCGCAATTCGTAAAGTGGCCAAAGGTGAGAAATATCTTAGTGCCGAGATAGCACAAAAAATGG
CAATTAATAGTCTCCAGGAGTCTCAGGATTCCCCCTTTGATTTATTGTCTGAAAGAGAAATGCAAGTCATGTTGATGATT
ACTAGCGGCATGAATGTACAAGACATTGCTGATAGATTATTTTTAAGTAGTAAAACCATCAATGGCTATCGATATAGGAT
GTTTGAAAAATTGGGGATTAAAAATGATGTGGAGCTTACTTATTTGGCTATGAAGCACCGCATTATTGAGCACCCCAATG
ATTTGTCACAAGATGATTAG

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(4-116)

Bacterial regulatory proteins, luxR family (GerE)

(148-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

99.543

100

0.995
  letA Legionella pneumophila strain ERS1305867

99.543

100

0.995

Multiple sequence alignment