Detailed information NTG0192875

Bioinformatically predicted

Overview

• Name: braS
• Type: Regulator
• Locus tag: A7U44_RS07400
• Genome accession: NZ_CP016856
• Coordinates: 1482615..1483502 (+)
• Length: 295 a.a.
• NCBI ID: WP_000143420.1
• Uniprot ID: A0A2S6DP21
• Organism: Staphylococcus aureus strain 2148.N
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1477615..1488502

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A7U44_RS07370 (A7U44_0094)	-	1478347..1479108 (+)	762	WP_000323447.1	alpha/beta hydrolase	-
A7U44_RS07375 (A7U44_0095)	-	1479353..1479808 (+)	456	WP_000106185.1	MarR family winged helix-turn-helix transcriptional regulator	-
A7U44_RS14430 (A7U44_03995)	-	1479930..1480031 (+)	102	WP_000731972.1	SE2200 family small protein	-
A7U44_RS07385 (A7U44_0096)	-	1480091..1481515 (-)	1425	WP_000953762.1	alkaline phosphatase	-
A7U44_RS07390 (A7U44_0097)	-	1481713..1481913 (+)	201	WP_000604727.1	hypothetical protein	-
A7U44_RS07395 (A7U44_0098)	braR	1481939..1482604 (+)	666	WP_000697879.1	nisin susceptibility-associated two-component system response regulator NsaR	Regulator
A7U44_RS07400 (A7U44_0099)	braS	1482615..1483502 (+)	888	WP_000143420.1	nisin susceptibility-associated two-component system sensor histidine kinase NsaS	Regulator
A7U44_RS07405 (A7U44_0100)	-	1483611..1484366 (+)	756	WP_000923760.1	ABC transporter ATP-binding protein	-
A7U44_RS07410 (A7U44_0101)	-	1484363..1486363 (+)	2001	WP_000776739.1	ABC transporter permease	-
A7U44_RS07415 (A7U44_04000)	-	1487022..1487135 (+)	114	Protein_1399	hypothetical protein	-
A7U44_RS07425 (A7U44_04010)	-	1487517..1487777 (+)	261	WP_001789910.1	hypothetical protein	-
A7U44_RS07430 (A7U44_0103)	-	1487787..1488284 (+)	498	WP_001065269.1	glutathione peroxidase	-
A7U44_RS07435 (A7U44_04015)	-	1488392..1488484 (-)	93	WP_010956583.1	hypothetical protein	-

Sequence

Protein

• Length: 295 a.a.
• Molecular weight: 34045.32 Da
• Isoelectric Point: 5.8962

>NTDB_id=192875 A7U44_RS07400 WP_000143420.1 1482615..1483502(+) (braS) [Staphylococcus aureus strain 2148.N]
MTFLKSITQEIAIVIVIFALFGLMFYLYHLPLEAYLLALGVILLLLLIFIGIKYLSFVKTISQQQQIENLENALYQLKNE
QIEYKNDVESYFLTWVHQMKTPITAAQLLLERDEPNVVNRVRQEVIQIDNYTSLALSYLKLLNETSDISVTKISINNIIR
PIIMKYSIQFIDQKTKIHYEPCHHEVLTDVRWTSLMIEQLINNALKYARGKDIWIEFDEQSNQLYVKDNGIGISEADLPK
IFDKGYSGYNGQRQSNSSGIGLFIVKQISTHTNHPVSVVSKQNEGTTFTIQFPDE

Nucleotide

• Length: 888 bp

>NTDB_id=192875 A7U44_RS07400 WP_000143420.1 1482615..1483502(+) (braS) [Staphylococcus aureus strain 2148.N]
ATGACCTTTCTTAAAAGTATTACTCAGGAAATAGCAATAGTCATAGTTATTTTTGCTTTATTTGGCTTAATGTTTTACCT
GTATCATTTGCCATTAGAAGCATATTTACTAGCACTTGGCGTTATTTTATTATTATTACTCATATTCATAGGTATTAAAT
ATTTAAGTTTTGTAAAAACTATAAGCCAACAACAACAAATTGAAAACTTAGAAAATGCGTTGTATCAGCTTAAAAATGAA
CAAATTGAATATAAAAATGATGTAGAGAGCTACTTTTTAACATGGGTACATCAAATGAAAACACCCATTACTGCAGCACA
ACTGTTACTTGAAAGAGATGAGCCTAATGTTGTGAATCGTGTTCGTCAAGAGGTTATTCAAATTGATAACTATACAAGTT
TAGCACTTAGTTATTTAAAGTTATTAAATGAAACTTCTGATATTTCTGTCACTAAAATTTCGATTAATAATATCATTCGC
CCAATTATTATGAAATATTCAATACAGTTTATTGATCAAAAAACAAAAATCCATTATGAACCTTGTCATCACGAAGTATT
AACTGACGTTAGATGGACCTCTTTAATGATAGAACAATTAATAAATAATGCACTTAAGTATGCGAGAGGTAAAGATATAT
GGATTGAATTTGATGAGCAATCCAATCAATTATACGTAAAAGATAATGGTATCGGTATTAGTGAAGCGGACTTGCCTAAA
ATATTTGATAAGGGCTATTCAGGTTATAATGGCCAGCGCCAAAGTAACTCAAGTGGGATTGGTTTATTTATCGTAAAACA
AATTTCAACACACACAAACCATCCTGTTTCAGTCGTATCTAAACAAAATGAGGGTACAACATTTACGATTCAATTTCCAG
ATGAATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (191-294)

3D structure

• AlphaFold DB: A0A2S6DP21

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braS	Staphylococcus aureus N315	99.322	100	0.993