Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   A7U44_RS04240 Genome accession   NZ_CP016856
Coordinates   839720..840289 (-) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain 2148.N     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 834720..845289
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A7U44_RS04195 (A7U44_2271) - 835194..835802 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  A7U44_RS04200 (A7U44_2272) rplL 835977..836345 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  A7U44_RS04205 (A7U44_2273) rplJ 836388..836888 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  A7U44_RS04215 (A7U44_2274) rplA 837160..837852 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  A7U44_RS04220 (A7U44_2275) rplK 838060..838482 (-) 423 WP_001085791.1 50S ribosomal protein L11 -
  A7U44_RS04225 (A7U44_2276) nusG 838663..839211 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  A7U44_RS04230 (A7U44_2277) secE 839224..839406 (-) 183 WP_001074473.1 preprotein translocase subunit SecE -
  A7U44_RS04235 (A7U44_03505) rpmG 839462..839605 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  A7U44_RS04240 (A7U44_2278) sigH 839720..840289 (-) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  A7U44_RS04245 (A7U44_2279) - 840370..840894 (-) 525 WP_000664738.1 NYN domain-containing protein -
  A7U44_RS04250 (A7U44_2280) rlmB 840894..841640 (-) 747 WP_000390332.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  A7U44_RS04255 (A7U44_2281) - 841648..842052 (-) 405 WP_078259023.1 Mini-ribonuclease 3 -
  A7U44_RS04260 (A7U44_2282) cysS 842045..843445 (-) 1401 WP_000631974.1 cysteine--tRNA ligase -
  A7U44_RS04265 (A7U44_03510) cysE 843429..844076 (-) 648 WP_001805237.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=192868 A7U44_RS04240 WP_000872873.1 839720..840289(-) (sigH) [Staphylococcus aureus strain 2148.N]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=192868 A7U44_RS04240 WP_000872873.1 839720..840289(-) (sigH) [Staphylococcus aureus strain 2148.N]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984

Multiple sequence alignment