Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6L58_RS14300 Genome accession   NZ_CP016682
Coordinates   709774..710238 (+) Length   154 a.a.
NCBI ID   WP_164967094.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M24705     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 709939..727427 709774..710238 flank -299
IS/Tn 710928..711581 709774..710238 flank 690


Gene organization within MGE regions


Location: 709774..727427
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L58_RS14300 (A6L58_03690) comE 709774..710238 (+) 465 WP_164967094.1 helix-hairpin-helix domain-containing protein Machinery gene
  A6L58_RS14650 - 710350..710808 (+) 459 WP_002234522.1 hypothetical protein -
  A6L58_RS03700 (A6L58_03700) - 710928..711581 (+) 654 WP_019742811.1 IS1595 family transposase -
  A6L58_RS03705 (A6L58_03705) - 711746..711955 (+) 210 Protein_685 transposase -
  A6L58_RS03710 (A6L58_03710) - 711937..712194 (-) 258 WP_002231679.1 membrane protein -
  A6L58_RS13680 - 712472..712699 (+) 228 WP_153310284.1 hypothetical protein -
  A6L58_RS03720 (A6L58_03720) aroG 712861..713916 (+) 1056 WP_002212267.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  A6L58_RS03725 (A6L58_03725) - 713984..714472 (+) 489 WP_002218701.1 dihydrofolate reductase -
  A6L58_RS03730 (A6L58_03730) - 714822..715298 (-) 477 WP_002231682.1 CYTH domain-containing protein -
  A6L58_RS03735 (A6L58_03735) - 715310..715738 (-) 429 WP_002212270.1 CopD family protein -
  A6L58_RS03745 (A6L58_03745) - 715850..716095 (+) 246 WP_002212272.1 hypothetical protein -
  A6L58_RS14900 - 717473..717646 (+) 174 WP_269465802.1 hypothetical protein -
  A6L58_RS14905 (A6L58_03750) - 717773..718261 (+) 489 WP_002258458.1 hypothetical protein -
  A6L58_RS03755 (A6L58_03755) - 718274..718951 (-) 678 WP_002215827.1 IS1595-like element ISNme3 family transposase -
  A6L58_RS03760 (A6L58_03760) autA 718999..720384 (+) 1386 Protein_696 autoaggregation autotransporter AutA -
  A6L58_RS03765 (A6L58_03765) - 720626..722092 (+) 1467 WP_065824894.1 surface lipoprotein assembly modifier -
  A6L58_RS03770 (A6L58_03770) - 722293..723261 (-) 969 WP_002251034.1 hypothetical protein -
  A6L58_RS03775 (A6L58_03775) - 723339..724631 (+) 1293 WP_002220262.1 M23 family metallopeptidase -
  A6L58_RS15025 - 725067..725278 (-) 212 Protein_700 hypothetical protein -
  A6L58_RS03780 (A6L58_03780) - 725570..726256 (-) 687 WP_002212282.1 7-cyano-7-deazaguanine/7-aminomethyl-7- deazaguanine transporter -
  A6L58_RS03785 (A6L58_03785) queF 726331..726804 (-) 474 WP_002234526.1 preQ(1) synthase -
  A6L58_RS03790 (A6L58_03790) - 727068..727427 (+) 360 WP_002221979.1 immunity 8 family protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16442.72 Da        Isoelectric Point: 10.7894

>NTDB_id=191744 A6L58_RS14300 WP_164967094.1 709774..710238(+) (comE) [Neisseria meningitidis strain M24705]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPALPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=191744 A6L58_RS14300 WP_164967094.1 709774..710238(+) (comE) [Neisseria meningitidis strain M24705]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734

Multiple sequence alignment