Detailed information
Bioinformatically predicted
Overview
| Name | comE | Type | Machinery gene |
| Locus tag | A6L58_RS14265 | Genome accession | NZ_CP016682 |
| Coordinates | 460846..461310 (+) | Length | 154 a.a. |
| NCBI ID | WP_164742033.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis strain M24705 | ||
| Function | DNA binding (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 454665..487180 | 460846..461310 | within | 0 |
Gene organization within MGE regions
Location: 454665..487180
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A6L58_RS02325 (A6L58_02325) | dksA | 454665..455081 (+) | 417 | WP_002231430.1 | RNA polymerase-binding protein DksA | - |
| A6L58_RS14265 | comE | 460846..461310 (+) | 465 | WP_164742033.1 | ComEA family DNA-binding protein | Machinery gene |
| A6L58_RS02375 (A6L58_02375) | dnaJ | 461580..462701 (+) | 1122 | WP_002235332.1 | molecular chaperone DnaJ | - |
| A6L58_RS02380 (A6L58_02380) | - | 462897..464915 (+) | 2019 | WP_002216177.1 | OPT family oligopeptide transporter | - |
| A6L58_RS02385 (A6L58_02385) | rfbC | 464959..465516 (-) | 558 | WP_002234441.1 | dTDP-4-dehydrorhamnose 3,5-epimerase | - |
| A6L58_RS02390 (A6L58_02390) | rfbA | 465561..466451 (-) | 891 | WP_002258018.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
| A6L58_RS02395 (A6L58_02395) | rfbB | 466648..467730 (-) | 1083 | WP_002258424.1 | dTDP-glucose 4,6-dehydratase | - |
| A6L58_RS14615 (A6L58_02400) | galE | 467731..468351 (-) | 621 | Protein_443 | UDP-glucose 4-epimerase GalE | - |
| A6L58_RS14620 (A6L58_02405) | - | 468430..468774 (-) | 345 | WP_002231447.1 | DNA adenine methylase | - |
| A6L58_RS14820 | - | 468767..468961 (-) | 195 | WP_002215282.1 | DNA cytosine methyltransferase | - |
| A6L58_RS02410 (A6L58_02410) | - | 468939..469715 (-) | 777 | WP_002259546.1 | DNA cytosine methyltransferase | - |
| A6L58_RS02415 (A6L58_02415) | - | 469800..472073 (-) | 2274 | WP_002230176.1 | Tex family protein | - |
| A6L58_RS02420 (A6L58_02420) | - | 472138..472788 (-) | 651 | WP_002215285.1 | ABC transporter ATP-binding protein | - |
| A6L58_RS02425 (A6L58_02425) | - | 472785..473582 (-) | 798 | WP_002218515.1 | ABC transporter permease | - |
| A6L58_RS02430 (A6L58_02430) | ctrB | 473582..474745 (-) | 1164 | WP_002215287.1 | capsule polysaccharide export protein CtrB | - |
| A6L58_RS02435 (A6L58_02435) | ctrA | 474760..475935 (-) | 1176 | WP_002215290.1 | capsule polysaccharide export outer membrane protein CtrA | - |
| A6L58_RS02440 (A6L58_02440) | neuC | 476070..477203 (+) | 1134 | WP_002224373.1 | UDP-N-acetylglucosamine 2-epimerase | - |
| A6L58_RS02445 (A6L58_02445) | neuA | 477207..477893 (+) | 687 | WP_002215295.1 | N-acylneuraminate cytidylyltransferase | - |
| A6L58_RS02450 (A6L58_02450) | siaC | 477894..478943 (+) | 1050 | WP_002228845.1 | polysialic acid capsule biosynthesis protein SiaC | - |
| A6L58_RS02455 (A6L58_02455) | - | 479095..482208 (+) | 3114 | WP_002239419.1 | glycosyltransferase | - |
| A6L58_RS11945 | - | 482509..483260 (+) | 752 | WP_096001759.1 | IS5-like element IS1301 family transposase | - |
| A6L58_RS11950 | - | 483257..483769 (+) | 513 | WP_228840111.1 | acyltransferase | - |
| A6L58_RS02470 (A6L58_02470) | - | 483820..484497 (+) | 678 | WP_002215827.1 | IS1595-like element ISNme3 family transposase | - |
| A6L58_RS02475 (A6L58_02475) | - | 484547..485716 (+) | 1170 | WP_019273883.1 | DUF6716 putative glycosyltransferase | - |
| A6L58_RS02480 (A6L58_02480) | - | 485764..486417 (+) | 654 | Protein_460 | UTP--glucose-1-phosphate uridylyltransferase | - |
Sequence
Protein
Download Length: 154 a.a. Molecular weight: 16514.78 Da Isoelectric Point: 10.6993
>NTDB_id=191743 A6L58_RS14265 WP_164742033.1 460846..461310(+) (comE) [Neisseria meningitidis strain M24705]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
Nucleotide
Download Length: 465 bp
>NTDB_id=191743 A6L58_RS14265 WP_164742033.1 460846..461310(+) (comE) [Neisseria meningitidis strain M24705]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTGAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTGAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |