Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6L50_RS14940 Genome accession   NZ_CP016680
Coordinates   1655499..1655963 (+) Length   154 a.a.
NCBI ID   WP_164742033.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22822     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1655664..1665505 1655499..1655963 flank -299


Gene organization within MGE regions


Location: 1655499..1665505
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L50_RS14940 comE 1655499..1655963 (+) 465 WP_164742033.1 ComEA family DNA-binding protein Machinery gene
  A6L50_RS08715 (A6L50_08715) dnaJ 1656233..1657354 (+) 1122 WP_002235332.1 molecular chaperone DnaJ -
  A6L50_RS08720 (A6L50_08720) - 1657550..1659568 (+) 2019 WP_002216177.1 OPT family oligopeptide transporter -
  A6L50_RS08725 (A6L50_08725) rfbC 1659612..1660169 (-) 558 WP_002234441.1 dTDP-4-dehydrorhamnose 3,5-epimerase -
  A6L50_RS08730 (A6L50_08730) rfbA 1660214..1661104 (-) 891 WP_002258018.1 glucose-1-phosphate thymidylyltransferase RfbA -
  A6L50_RS08740 (A6L50_08740) - 1661380..1662345 (+) 966 WP_002217985.1 IS30-like element IS1655 family transposase -
  A6L50_RS08745 (A6L50_08745) rfbB 1662384..1663466 (-) 1083 WP_002258424.1 dTDP-glucose 4,6-dehydratase -
  A6L50_RS15370 (A6L50_08750) galE 1663467..1664087 (-) 621 Protein_1610 UDP-glucose 4-epimerase GalE -
  A6L50_RS15375 (A6L50_08755) - 1664166..1664510 (-) 345 WP_002231447.1 DNA adenine methylase -
  A6L50_RS15450 - 1664503..1664697 (-) 195 WP_002215282.1 DNA cytosine methyltransferase -
  A6L50_RS08760 (A6L50_08760) - 1664675..1665505 (-) 831 WP_002215283.1 DNA cytosine methyltransferase -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16514.78 Da        Isoelectric Point: 10.6993

>NTDB_id=191647 A6L50_RS14940 WP_164742033.1 1655499..1655963(+) (comE) [Neisseria meningitidis strain M22822]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=191647 A6L50_RS14940 WP_164742033.1 1655499..1655963(+) (comE) [Neisseria meningitidis strain M22822]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74
  comE Neisseria gonorrhoeae MS11

93.443

79.221

0.74

Multiple sequence alignment