Detailed information NTG0191639

Bioinformatically predicted

Overview

• Name: pilD
• Type: Machinery gene
• Locus tag: A6L50_RS10210
• Genome accession: NZ_CP016680
• Coordinates: 1933981..1934841 (-)
• Length: 286 a.a.
• NCBI ID: WP_002223365.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22822
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1928981..1939841

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L50_RS10180 (A6L50_10180)	ispB	1929467..1930441 (+)	975	WP_002256366.1	octaprenyl diphosphate synthase	-
A6L50_RS10185 (A6L50_10185)	-	1930446..1930892 (+)	447	WP_002220271.1	DUF441 domain-containing protein	-
A6L50_RS10195 (A6L50_10195)	pilF	1931384..1933060 (+)	1677	WP_002221967.1	type IV-A pilus assembly ATPase PilB	Machinery gene
A6L50_RS10200 (A6L50_10200)	-	1933145..1933354 (-)	210	WP_002226982.1	DNA gyrase inhibitor YacG	-
A6L50_RS10205 (A6L50_10205)	coaE	1933347..1933979 (-)	633	WP_002258461.1	dephospho-CoA kinase	-
A6L50_RS10210 (A6L50_10210)	pilD	1933981..1934841 (-)	861	WP_002223365.1	prepilin peptidase	Machinery gene
A6L50_RS10215 (A6L50_10215)	pilG	1934915..1936147 (-)	1233	WP_002216405.1	type 4 pilus assembly protein PilG	Machinery gene
A6L50_RS10220 (A6L50_10220)	pgi	1936657..1938300 (+)	1644	WP_002220279.1	glucose-6-phosphate isomerase	-
A6L50_RS10225 (A6L50_10225)	-	1938270..1938500 (+)	231	WP_025462714.1	hypothetical protein	-
A6L50_RS10230 (A6L50_10230)	dapD	1938510..1939331 (+)	822	WP_002212339.1	2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase	-

Sequence

Protein

• Length: 286 a.a.
• Molecular weight: 31363.39 Da
• Isoelectric Point: 8.2213

>NTDB_id=191639 A6L50_RS10210 WP_002223365.1 1933981..1934841(-) (pilD) [Neisseria meningitidis strain M22822]
MSDLSVLSPFAVPLAAVFGLLVGSFLNVVIYRVPVMMERGWTVFAKEYLNLPLTEEESRTFNLMKPDSCCPKCRVPIRAW
QNIPIVSYLLLRGKCASCQTKISIRYPLIELLTGVLFGLIAWQYGWSWITLGGLVLTAFLISLTFIDADTQYLPDSMTLL
LIWLGLIFNLDGGFVPLQSAVLGAVAGYGSIWLLCAVYKLIKGETGMGNGDFKLIAALGAWLGISALPVLIFVSSLIGLV
AAIVMRVAKGQHFAFGPALTVSGWIIFTANDSVWRAVNWWLTHPVL

Nucleotide

• Length: 861 bp

>NTDB_id=191639 A6L50_RS10210 WP_002223365.1 1933981..1934841(-) (pilD) [Neisseria meningitidis strain M22822]
ATGTCTGATTTGTCTGTATTGTCGCCGTTTGCCGTGCCTTTGGCAGCGGTGTTCGGGCTGCTGGTCGGAAGTTTCTTAAA
TGTCGTCATTTACCGCGTGCCGGTCATGATGGAACGCGGCTGGACGGTATTTGCCAAAGAATATTTAAACCTGCCGCTGA
CCGAAGAGGAAAGCCGTACCTTCAACCTGATGAAGCCGGATTCCTGCTGTCCCAAATGTCGCGTGCCGATACGCGCGTGG
CAGAACATCCCGATTGTCAGCTACCTGCTCCTGCGCGGCAAATGCGCTTCCTGCCAAACCAAAATCAGCATACGTTATCC
CTTAATCGAGCTGCTGACCGGCGTATTGTTCGGGCTGATCGCCTGGCAATACGGCTGGTCTTGGATTACGCTGGGCGGAT
TGGTACTGACCGCGTTTCTGATTTCCCTGACCTTTATCGATGCGGACACCCAATACCTGCCCGACTCGATGACACTGCTC
TTGATTTGGCTGGGACTGATATTTAATTTGGACGGCGGCTTCGTGCCTTTGCAGTCTGCCGTTTTAGGTGCGGTTGCCGG
CTATGGTTCGATATGGCTTTTATGCGCGGTATATAAACTGATTAAAGGCGAAACCGGTATGGGCAACGGAGATTTCAAAC
TGATTGCCGCATTGGGCGCGTGGCTCGGCATATCCGCATTGCCCGTGCTGATTTTTGTTTCCTCGCTGATCGGTTTGGTC
GCGGCAATCGTTATGCGCGTCGCCAAGGGGCAGCATTTTGCCTTCGGCCCCGCACTGACAGTTTCGGGCTGGATAATTTT
TACGGCAAACGATTCCGTATGGCGGGCGGTCAACTGGTGGCTGACCCATCCGGTGCTGTAA

Domains

Predicted by InterproScan.

• Type IV leader peptidase family (Peptidase_A24) (134-242)

• Bacterial Peptidase A24 N-terminal domain (A24_N_bact) (17-124)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilD	Neisseria gonorrhoeae MS11	95.439	99.65	0.951
pilD	Vibrio cholerae strain A1552	44.444	100	0.448
pilD	Vibrio campbellii strain DS40M4	44.928	96.503	0.434
pilD	Acinetobacter baumannii D1279779	46.591	92.308	0.43
pilD	Acinetobacter nosocomialis M2	46.591	92.308	0.43