Detailed information NTG0191595

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: A6L34_RS09840
• Genome accession: NZ_CP016679
• Coordinates: 1896477..1896941 (-)
• Length: 154 a.a.
• NCBI ID: WP_011798742.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M22740
• Function: DNA binding (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	1880928..1903157	1896477..1896941	within	0

Gene organization within MGE regions

Location: 1880928..1903157

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L34_RS09775 (A6L34_09775)	neuA	1880928..1881614 (+)	687	WP_002215295.1	N-acylneuraminate cytidylyltransferase	-
A6L34_RS09780 (A6L34_09780)	siaC	1881615..1882664 (+)	1050	WP_002228845.1	polysialic acid capsule biosynthesis protein SiaC	-
A6L34_RS09785 (A6L34_09785)	-	1882816..1885929 (+)	3114	WP_002248201.1	glycosyltransferase	-
A6L34_RS09790 (A6L34_09790)	-	1886200..1886877 (+)	678	WP_002215827.1	IS1595-like element ISNme3 family transposase	-
A6L34_RS09795 (A6L34_09795)	-	1886927..1888096 (+)	1170	WP_019273883.1	DUF6716 putative glycosyltransferase	-
A6L34_RS09800 (A6L34_09800)	galU	1888144..1889007 (+)	864	WP_002248199.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
A6L34_RS09805 (A6L34_09805)	galE	1889090..1890106 (+)	1017	WP_002248198.1	UDP-glucose 4-epimerase GalE	-
A6L34_RS09810 (A6L34_09810)	rfbB	1890222..1891289 (+)	1068	WP_002248455.1	dTDP-glucose 4,6-dehydratase	-
A6L34_RS09815 (A6L34_09815)	rfbA	1891352..1892218 (+)	867	WP_002224369.1	glucose-1-phosphate thymidylyltransferase RfbA	-
A6L34_RS09820 (A6L34_09820)	rfbC	1892272..1892829 (+)	558	WP_002224368.1	dTDP-4-dehydrorhamnose 3,5-epimerase	-
A6L34_RS09825 (A6L34_09825)	-	1892873..1894891 (-)	2019	WP_002224367.1	OPT family oligopeptide transporter	-
A6L34_RS09830 (A6L34_09830)	dnaJ	1895087..1896208 (-)	1122	WP_002215274.1	molecular chaperone DnaJ	-
A6L34_RS09840 (A6L34_09840)	comE	1896477..1896941 (-)	465	WP_011798742.1	ComEA family DNA-binding protein	Machinery gene
A6L34_RS09875 (A6L34_09875)	dksA	1902741..1903157 (-)	417	WP_002215267.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 154 a.a.
• Molecular weight: 16605.84 Da
• Isoelectric Point: 10.8773

>NTDB_id=191595 A6L34_RS09840 WP_011798742.1 1896477..1896941(-) (comE) [Neisseria meningitidis strain M22740]
MLYPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPADKK

Nucleotide

• Length: 465 bp

>NTDB_id=191595 A6L34_RS09840 WP_011798742.1 1896477..1896941(-) (comE) [Neisseria meningitidis strain M22740]
TTGCTTTACCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (75-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Neisseria gonorrhoeae MS11	93.443	79.221	0.74
comE	Neisseria gonorrhoeae MS11	93.443	79.221	0.74
comE	Neisseria gonorrhoeae MS11	93.443	79.221	0.74
comE	Neisseria gonorrhoeae MS11	93.443	79.221	0.74