Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   A6M07_RS05415 Genome accession   NZ_CP016676
Coordinates   1042371..1045340 (+) Length   989 a.a.
NCBI ID   WP_065825006.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M25476     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1037371..1050340
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6M07_RS05380 (A6M07_05380) murU 1037659..1038354 (-) 696 WP_065826262.1 N-acetylmuramate alpha-1-phosphate uridylyltransferase MurU -
  A6M07_RS05385 (A6M07_05385) hpaC 1038372..1038872 (-) 501 WP_002248346.1 4-hydroxyphenylacetate 3-monooxygenase, reductase component -
  A6M07_RS05390 (A6M07_05390) nadR 1038987..1039427 (-) 441 WP_002221507.1 MarR family adhesin repressor NadR -
  A6M07_RS05400 (A6M07_05400) - 1039770..1040279 (-) 510 WP_002259078.1 protein disulfide oxidoreductase -
  A6M07_RS05410 (A6M07_05410) apbC 1040644..1041723 (+) 1080 WP_002259079.1 iron-sulfur cluster carrier protein ApbC -
  A6M07_RS14610 pilC 1042252..1042374 (+) 123 WP_324248582.1 hypothetical protein Machinery gene
  A6M07_RS05415 (A6M07_05415) pilC 1042371..1045340 (+) 2970 WP_065825006.1 PilC family type IV pilus tip adhesin Machinery gene
  A6M07_RS05425 (A6M07_05425) carA 1047321..1048454 (+) 1134 WP_002245197.1 glutamine-hydrolyzing carbamoyl-phosphate synthase small subunit -
  A6M07_RS05430 (A6M07_05430) - 1048500..1048637 (+) 138 WP_002214606.1 VOC family protein -
  A6M07_RS05445 (A6M07_05445) - 1049217..1049606 (+) 390 WP_002221514.1 endonuclease domain-containing protein -
  A6M07_RS13530 - 1049610..1049777 (+) 168 WP_153312129.1 hypothetical protein -

Sequence

Protein


Download         Length: 989 a.a.        Molecular weight: 108600.37 Da        Isoelectric Point: 9.7230

>NTDB_id=191438 A6M07_RS05415 WP_065825006.1 1042371..1045340(+) (pilC) [Neisseria meningitidis strain M25476]
MNEQNQPNVKQEGSYSTLREKDRKRKFDFNANRGGGGSVFFDNTDTLVSQQRGTAVFGTATYLPPYGKVSGFDEKRLTER
GNALNWINTTHPGLIGYSYAGVVCRDSTSCPKLVYKTRFSFDNTGLAKNAGSLDRHPDPSRENSPIYKLKDHPWLGVSFN
LGSENTVKNGNSFNKLISSFSEDNNNQTIVSTTEGSPISLSDQQREHTAVVYYLNAKLHLLDKKQIQNITDKTVQLGTLR
PRVETTGRSWLNFWATWKIEDKGNITVRLDLPEVKAGRCVNANNPNKSTKAPSPALTAPALWFGPVQNGKAEMYSASVST
YPDSSSSRIFLQNLKRKNDSNRPGRHSLETLTENDIKSRQPNFTGRQTIIRLDSGVQQIKLQGNEVANFNRNDGKNDTFG
IVSEYGLTPDANEWKKVLLPWTVRAFNDDGRFNTVNKEENNGKPKYSQRYRIRENGNNGNNGKRDLGDIVNSPIVAVGEY
LATSANDGMVHIFKQSGGDKRSYNLKLSYIPGTMPRKDIQNTESTLAKELRAFAEKSYVGDRYGVDGGFVLRQVELSGKK
HVFMFGAMGFGGRGAYALDLTKAENGNPTAVSLFDVKHDNNGKNSNNSVQLGYTVGTPQIGKTHNGKYAAFLASGYATKT
IDSTDNKTALYVYDLESSGTLIKKIDVPGGKGGLSSPTLVDKDLDGIVDIAYAGDRGGNMYRFDLSGNNPNSWTVRPIFE
GTKPITSAPAISQLKDKRVVIFGTGSDLSEDDVDNKDIQHVYGIFDNDTDTGTAQDGQGKGLLEQVLSEENKTLFLTDYK
RSNGSGSKGWMVKLQPRQRVTVKPTVVLRTAFVTIRKYEDNGCGAETAILGINTADGGKLTKKSARPIVPAANQAVAQYS
GHKQTTKGKSIPIGCMQKGNEIVCPNGYVYDKPVNVRYLDEKKTDGFSTTADGDAGGSGIDPAGKRSGKNNRCFSQKGVR
TLLMNDLDSLDITGPTCGMKRISWREVFY

Nucleotide


Download         Length: 2970 bp        

>NTDB_id=191438 A6M07_RS05415 WP_065825006.1 1042371..1045340(+) (pilC) [Neisseria meningitidis strain M25476]
ATGAACGAACAAAATCAGCCGAATGTAAAGCAGGAGGGTTCATATTCAACCTTAAGGGAAAAAGACAGGAAACGCAAATT
TGACTTTAATGCGAACAGAGGGGGTGGAGGTTCTGTCTTTTTCGACAATACCGATACCCTTGTTTCCCAACAAAGAGGTA
CTGCCGTTTTTGGCACAGCCACCTACCTGCCGCCCTACGGCAAGGTTTCCGGTTTTGATGAAAAGAGGCTGACAGAGCGC
GGCAATGCCCTTAATTGGATTAATACGACCCACCCAGGGTTGATAGGCTACAGCTACGCCGGTGTCGTATGCAGAGACAG
CACAAGCTGTCCCAAACTTGTCTATAAAACCCGATTTTCCTTCGACAACACCGGTTTGGCAAAAAATGCGGGCAGCCTGG
ATAGGCACCCGGACCCAAGCCGCGAAAATTCGCCCATTTACAAATTGAAGGATCATCCATGGTTGGGCGTGTCTTTCAAT
TTGGGCAGCGAGAATACCGTCAAAAATGGCAACTCATTCAACAAATTGATATCTTCTTTTAGTGAAGACAATAATAATCA
AACCATCGTCTCTACGACAGAAGGCTCCCCTATTTCCCTTAGCGACCAGCAGCGCGAACATACCGCCGTGGTCTATTATC
TGAACGCCAAGCTGCACCTGCTGGATAAAAAACAGATTCAAAATATCACCGACAAAACAGTGCAGTTGGGCACCTTGAGA
CCGCGCGTCGAGACGACAGGACGAAGCTGGCTAAATTTTTGGGCTACGTGGAAGATTGAAGATAAAGGGAACATTACAGT
CCGCCTCGACCTGCCGGAAGTCAAAGCAGGCCGCTGCGTCAACGCAAATAACCCCAATAAGAGTACCAAAGCCCCTTCCC
CCGCACTGACCGCCCCCGCGCTGTGGTTCGGCCCTGTGCAAAATGGTAAGGCGGAGATGTATTCCGCTTCGGTTTCCACC
TACCCCGACAGTTCGAGCAGCCGCATCTTCCTTCAAAATCTGAAAAGAAAAAACGACTCCAACAGACCCGGCCGCCATTC
CCTCGAAACCTTGACTGAGAACGATATTAAAAGTCGACAGCCGAATTTCACAGGGCGGCAAACAATCATCCGATTGGATA
GCGGCGTACAGCAGATCAAACTTCAAGGCAATGAGGTCGCCAATTTTAATAGAAATGACGGCAAAAACGACACTTTCGGC
ATTGTTAGTGAATATGGCCTCACGCCTGATGCCAATGAGTGGAAAAAAGTGCTGCTGCCTTGGACGGTTCGTGCTTTCAA
TGATGACGGTCGATTTAACACAGTCAACAAAGAAGAAAACAACGGCAAGCCAAAATACAGCCAAAGATACCGCATCCGCG
AAAACGGCAACAACGGCAACAACGGCAAGCGTGATTTGGGCGACATCGTCAACAGCCCCATCGTGGCGGTCGGCGAGTAT
TTGGCTACTTCCGCCAACGACGGGATGGTGCATATCTTCAAACAAAGCGGCGGGGACAAGCGCAGCTACAATCTGAAGCT
CAGTTATATCCCGGGTACGATGCCGCGCAAGGATATTCAAAACACCGAATCCACCCTTGCCAAAGAGCTGCGCGCCTTTG
CCGAAAAAAGCTATGTGGGCGACCGCTACGGCGTGGACGGCGGCTTTGTTTTGCGCCAAGTCGAACTGAGCGGGAAAAAA
CACGTGTTTATGTTCGGCGCGATGGGTTTTGGCGGCAGAGGCGCATACGCCTTGGATTTGACCAAAGCCGAAAACGGTAA
CCCGACCGCCGTTTCCCTGTTTGATGTCAAACATGACAATAATGGCAAGAATAGCAATAATAGCGTGCAATTAGGCTACA
CCGTCGGCACGCCGCAAATCGGCAAAACCCACAACGGCAAATACGCCGCCTTCCTCGCCTCCGGTTATGCGACTAAAACC
ATTGACAGCACAGACAATAAAACCGCGCTGTATGTGTATGATTTGGAAAGCAGCGGTACGCTGATTAAAAAAATCGATGT
ACCCGGCGGCAAGGGCGGGCTTTCGTCCCCCACGCTGGTGGATAAAGATTTGGACGGCATTGTTGATATCGCCTATGCCG
GCGATCGCGGCGGGAATATGTACCGCTTTGATTTAAGCGGCAACAACCCGAACAGTTGGACTGTACGCCCTATTTTTGAA
GGCACAAAACCGATTACTTCCGCGCCCGCCATTTCCCAACTGAAAGACAAACGCGTGGTCATCTTCGGCACGGGCAGTGA
TTTGAGTGAGGATGATGTGGACAACAAAGACATCCAACACGTTTACGGTATTTTTGACAATGACACAGACACGGGTACGG
CGCAAGACGGGCAGGGCAAAGGGCTGCTCGAGCAAGTGCTTAGTGAGGAAAATAAAACCTTATTCCTGACCGATTACAAG
CGATCCAACGGATCGGGCAGTAAGGGGTGGATGGTGAAATTGCAGCCCAGACAGCGCGTTACCGTCAAACCGACCGTGGT
ATTGCGTACCGCCTTTGTAACCATCCGCAAATATGAAGACAACGGCTGCGGCGCGGAAACCGCCATTTTGGGCATCAATA
CCGCCGACGGCGGCAAGCTGACCAAGAAAAGCGCGCGCCCGATTGTGCCGGCAGCCAATCAGGCTGTCGCGCAATATTCC
GGCCATAAGCAAACCACCAAAGGCAAATCCATCCCTATAGGTTGTATGCAAAAAGGCAATGAAATCGTCTGCCCGAACGG
ATATGTTTACGACAAACCGGTTAATGTGCGCTACCTGGACGAAAAGAAAACAGACGGATTTTCAACAACGGCAGACGGCG
ATGCGGGCGGCAGCGGTATAGACCCCGCCGGCAAGCGTTCCGGCAAAAACAACCGCTGCTTCTCCCAAAAAGGGGTGCGC
ACCCTGCTGATGAACGATTTGGACAGCTTGGACATTACCGGCCCGACGTGCGGTATGAAACGAATCAGCTGGCGTGAAGT
CTTCTACTGA

Domains

Predicted by InterproScan.

Neisseria PilC beta-propeller domain (T4P_PilY1)

(466-797)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Neisseria meningitidis A1493

80.976

100

0.822

Multiple sequence alignment