Detailed information
Bioinformatically predicted
Overview
| Name | comE | Type | Machinery gene |
| Locus tag | A6L42_RS14390 | Genome accession | NZ_CP016671 |
| Coordinates | 1747276..1747740 (-) | Length | 154 a.a. |
| NCBI ID | WP_164742033.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis strain M22783 | ||
| Function | DNA binding (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 1722870..1753921 | 1747276..1747740 | within | 0 |
Gene organization within MGE regions
Location: 1722870..1753921
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A6L42_RS09025 (A6L42_09025) | - | 1722870..1724039 (-) | 1170 | WP_019273883.1 | DUF6716 putative glycosyltransferase | - |
| A6L42_RS09030 (A6L42_09030) | - | 1724089..1724766 (-) | 678 | WP_002215827.1 | IS1595-like element ISNme3 family transposase | - |
| A6L42_RS12890 | - | 1724817..1725329 (-) | 513 | WP_228840111.1 | acyltransferase | - |
| A6L42_RS09045 (A6L42_09045) | - | 1726378..1729491 (-) | 3114 | WP_002239419.1 | glycosyltransferase | - |
| A6L42_RS09050 (A6L42_09050) | siaC | 1729643..1730692 (-) | 1050 | WP_002228845.1 | polysialic acid capsule biosynthesis protein SiaC | - |
| A6L42_RS09055 (A6L42_09055) | neuA | 1730693..1731379 (-) | 687 | WP_002215295.1 | N-acylneuraminate cytidylyltransferase | - |
| A6L42_RS09060 (A6L42_09060) | neuC | 1731383..1732516 (-) | 1134 | WP_002224373.1 | UDP-N-acetylglucosamine 2-epimerase | - |
| A6L42_RS09065 (A6L42_09065) | ctrA | 1732651..1733826 (+) | 1176 | WP_002215290.1 | capsule polysaccharide export outer membrane protein CtrA | - |
| A6L42_RS09070 (A6L42_09070) | ctrB | 1733841..1735004 (+) | 1164 | WP_002215287.1 | capsule polysaccharide export protein CtrB | - |
| A6L42_RS09075 (A6L42_09075) | - | 1735004..1735801 (+) | 798 | WP_002218515.1 | ABC transporter permease | - |
| A6L42_RS09080 (A6L42_09080) | - | 1735798..1736448 (+) | 651 | WP_002215285.1 | ABC transporter ATP-binding protein | - |
| A6L42_RS09085 (A6L42_09085) | - | 1736513..1738786 (+) | 2274 | WP_002230176.1 | Tex family protein | - |
| A6L42_RS09090 (A6L42_09090) | - | 1738817..1739647 (+) | 831 | WP_002215283.1 | DNA cytosine methyltransferase | - |
| A6L42_RS14750 | - | 1739625..1739819 (+) | 195 | WP_002215282.1 | DNA cytosine methyltransferase | - |
| A6L42_RS09095 (A6L42_09095) | - | 1739812..1740156 (+) | 345 | WP_002231447.1 | DNA adenine methylase | - |
| A6L42_RS09100 (A6L42_09100) | galE | 1740235..1740855 (+) | 621 | Protein_1683 | UDP-glucose 4-epimerase GalE | - |
| A6L42_RS09105 (A6L42_09105) | rfbB | 1740856..1741938 (+) | 1083 | WP_002258424.1 | dTDP-glucose 4,6-dehydratase | - |
| A6L42_RS09110 (A6L42_09110) | rfbA | 1742135..1743025 (+) | 891 | WP_002258018.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
| A6L42_RS09115 (A6L42_09115) | rfbC | 1743070..1743627 (+) | 558 | WP_002234441.1 | dTDP-4-dehydrorhamnose 3,5-epimerase | - |
| A6L42_RS09120 (A6L42_09120) | - | 1743671..1745689 (-) | 2019 | WP_002216177.1 | OPT family oligopeptide transporter | - |
| A6L42_RS09125 (A6L42_09125) | dnaJ | 1745885..1747006 (-) | 1122 | WP_002235332.1 | molecular chaperone DnaJ | - |
| A6L42_RS14390 | comE | 1747276..1747740 (-) | 465 | WP_164742033.1 | ComEA family DNA-binding protein | Machinery gene |
| A6L42_RS09170 (A6L42_09170) | dksA | 1753505..1753921 (-) | 417 | WP_002231430.1 | RNA polymerase-binding protein DksA | - |
Sequence
Protein
Download Length: 154 a.a. Molecular weight: 16514.78 Da Isoelectric Point: 10.6993
>NTDB_id=191223 A6L42_RS14390 WP_164742033.1 1747276..1747740(-) (comE) [Neisseria meningitidis strain M22783]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
Nucleotide
Download Length: 465 bp
>NTDB_id=191223 A6L42_RS14390 WP_164742033.1 1747276..1747740(-) (comE) [Neisseria meningitidis strain M22783]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTGAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTGAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGCGCGCCCGCACCAAAAGGCCCAGCTAAACCAGTGCTGCCCGCGGATAAAAAATAA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |
| comE | Neisseria gonorrhoeae MS11 |
93.443 |
79.221 |
0.74 |