Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6L42_RS14370 Genome accession   NZ_CP016671
Coordinates   1498141..1498605 (-) Length   154 a.a.
NCBI ID   WP_164993478.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22783     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 1489464..1508648 1498141..1498605 within 0
IS/Tn 1496798..1497451 1498141..1498605 flank 690


Gene organization within MGE regions


Location: 1489464..1508648
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L42_RS07745 (A6L42_07745) - 1489464..1490141 (+) 678 WP_002215827.1 IS1595-like element ISNme3 family transposase -
  A6L42_RS14810 (A6L42_07750) - 1490154..1490642 (-) 489 WP_002258458.1 hypothetical protein -
  A6L42_RS14815 - 1490769..1490906 (-) 138 WP_153317764.1 hypothetical protein -
  A6L42_RS07755 (A6L42_07755) - 1492284..1492529 (-) 246 WP_002212272.1 hypothetical protein -
  A6L42_RS07765 (A6L42_07765) - 1492641..1493069 (+) 429 WP_002212270.1 CopD family protein -
  A6L42_RS07770 (A6L42_07770) - 1493081..1493557 (+) 477 WP_002231682.1 CYTH domain-containing protein -
  A6L42_RS07775 (A6L42_07775) - 1493907..1494395 (-) 489 WP_002218701.1 dihydrofolate reductase -
  A6L42_RS07780 (A6L42_07780) aroG 1494463..1495518 (-) 1056 WP_002212267.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  A6L42_RS13965 - 1495680..1495907 (-) 228 WP_153310284.1 hypothetical protein -
  A6L42_RS07790 (A6L42_07790) - 1496185..1496442 (+) 258 WP_002231679.1 membrane protein -
  A6L42_RS07795 (A6L42_07795) - 1496424..1496633 (-) 210 Protein_1445 transposase -
  A6L42_RS07800 (A6L42_07800) - 1496798..1497451 (-) 654 WP_019742811.1 IS1595 family transposase -
  A6L42_RS14625 - 1497571..1498029 (-) 459 WP_002234522.1 hypothetical protein -
  A6L42_RS14370 (A6L42_07810) comE 1498141..1498605 (-) 465 WP_164993478.1 ComEA family DNA-binding protein Machinery gene
  A6L42_RS07845 (A6L42_07845) - 1504396..1505202 (-) 807 WP_002221447.1 cytochrome C assembly family protein -
  A6L42_RS07850 (A6L42_07850) ffh 1505422..1506792 (+) 1371 WP_002258651.1 signal recognition particle protein -
  A6L42_RS07855 (A6L42_07855) dsbA2 1507123..1507818 (-) 696 WP_002234519.1 thiol:disulfide interchange protein DsbA/DsbL Machinery gene
  A6L42_RS07860 (A6L42_07860) - 1507989..1508648 (-) 660 WP_002218694.1 NYN domain-containing protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16486.82 Da        Isoelectric Point: 10.9585

>NTDB_id=191222 A6L42_RS14370 WP_164993478.1 1498141..1498605(-) (comE) [Neisseria meningitidis strain M22783]
MLCPEKMSVMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPALPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=191222 A6L42_RS14370 WP_164993478.1 1498141..1498605(-) (comE) [Neisseria meningitidis strain M22783]
TTGCTTTGCCCGGAAAAAATGTCGGTGATGGCGGGACGGCATCCGTACGGTGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCAGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734

Multiple sequence alignment