Detailed information NTG0191139

Bioinformatically predicted

Overview

• Name: comE
• Type: Machinery gene
• Locus tag: A6L77_RS01475
• Genome accession: NZ_CP016670
• Coordinates: 271206..271670 (-)
• Length: 154 a.a.
• NCBI ID: WP_025463842.1
• Uniprot ID: -
• Organism: Neisseria meningitidis strain M25087
• Function: DNA binding (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
Genomic island	255657..277886	271206..271670	within	0

Gene organization within MGE regions

Location: 255657..277886

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
A6L77_RS01410 (A6L77_01410)	neuA	255657..256343 (+)	687	WP_002215295.1	N-acylneuraminate cytidylyltransferase	-
A6L77_RS01415 (A6L77_01415)	siaC	256344..257393 (+)	1050	WP_002228845.1	polysialic acid capsule biosynthesis protein SiaC	-
A6L77_RS01420 (A6L77_01420)	-	257545..260658 (+)	3114	WP_002248201.1	glycosyltransferase	-
A6L77_RS01425 (A6L77_01425)	-	260929..261606 (+)	678	WP_002215827.1	IS1595-like element ISNme3 family transposase	-
A6L77_RS01430 (A6L77_01430)	-	261656..262825 (+)	1170	WP_019273883.1	DUF6716 putative glycosyltransferase	-
A6L77_RS01435 (A6L77_01435)	galU	262873..263736 (+)	864	WP_002248199.1	UTP--glucose-1-phosphate uridylyltransferase GalU	-
A6L77_RS01440 (A6L77_01440)	galE	263819..264835 (+)	1017	WP_002248198.1	UDP-glucose 4-epimerase GalE	-
A6L77_RS01445 (A6L77_01445)	rfbB	264951..266018 (+)	1068	WP_002248455.1	dTDP-glucose 4,6-dehydratase	-
A6L77_RS01450 (A6L77_01450)	rfbA	266081..266947 (+)	867	WP_002224369.1	glucose-1-phosphate thymidylyltransferase RfbA	-
A6L77_RS01455 (A6L77_01455)	rfbC	267001..267558 (+)	558	WP_002224368.1	dTDP-4-dehydrorhamnose 3,5-epimerase	-
A6L77_RS01460 (A6L77_01460)	-	267602..269620 (-)	2019	WP_002224367.1	OPT family oligopeptide transporter	-
A6L77_RS01465 (A6L77_01465)	dnaJ	269816..270937 (-)	1122	WP_002215274.1	molecular chaperone DnaJ	-
A6L77_RS01475 (A6L77_01475)	comE	271206..271670 (-)	465	WP_025463842.1	ComEA family DNA-binding protein	Machinery gene
A6L77_RS01510 (A6L77_01510)	dksA	277470..277886 (-)	417	WP_002215267.1	RNA polymerase-binding protein DksA	-

Sequence

Protein

• Length: 154 a.a.
• Molecular weight: 16545.80 Da
• Isoelectric Point: 10.8645

>NTDB_id=191139 A6L77_RS01475 WP_025463842.1 271206..271670(-) (comE) [Neisseria meningitidis strain M25087]
MLCPEKMSGMAGRHPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKAPAKPVLPADKK

Nucleotide

• Length: 465 bp

>NTDB_id=191139 A6L77_RS01475 WP_025463842.1 271206..271670(-) (comE) [Neisseria meningitidis strain M25087]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACGGCATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTGGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCTGTCGGCGCGCCCGCACCAAAAGCCCCAGCCAAACCGGTGCTGCCCGCGGATAAAAAATAA

Domains

Predicted by InterproScan.

• Helix-hairpin-helix motif (HHH_3) (75-133)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comE	Neisseria gonorrhoeae MS11	93.443	79.221	0.74
comE	Neisseria gonorrhoeae MS11	93.443	79.221	0.74
comE	Neisseria gonorrhoeae MS11	93.443	79.221	0.74
comE	Neisseria gonorrhoeae MS11	93.443	79.221	0.74