Detailed information
Bioinformatically predicted
Overview
| Name | pilV | Type | Machinery gene |
| Locus tag | A6L33_RS01925 | Genome accession | NZ_CP016663 |
| Coordinates | 345476..346087 (-) | Length | 203 a.a. |
| NCBI ID | WP_002248273.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis strain M22722 | ||
| Function | repress natural transformation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Prophage | 302811..358803 | 345476..346087 | within | 0 |
Gene organization within MGE regions
Location: 302811..358803
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| A6L33_RS01650 (A6L33_01650) | - | 302811..303179 (+) | 369 | WP_002220735.1 | type II toxin-antitoxin system death-on-curing family toxin | - |
| A6L33_RS13945 | - | 303195..303365 (+) | 171 | WP_164728559.1 | hypothetical protein | - |
| A6L33_RS01655 (A6L33_01655) | - | 303617..304108 (+) | 492 | WP_002217437.1 | DUF4760 domain-containing protein | - |
| A6L33_RS01660 (A6L33_01660) | - | 304467..304703 (+) | 237 | WP_002217439.1 | AbrB/MazE/SpoVT family DNA-binding domain-containing protein | - |
| A6L33_RS01665 (A6L33_01665) | - | 304705..305052 (+) | 348 | WP_002217440.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| A6L33_RS01670 (A6L33_01670) | - | 305105..305614 (-) | 510 | WP_002220734.1 | hypothetical protein | - |
| A6L33_RS01675 (A6L33_01675) | - | 305626..306099 (-) | 474 | WP_002220733.1 | D-Ala-D-Ala carboxypeptidase family metallohydrolase | - |
| A6L33_RS01680 (A6L33_01680) | - | 306238..306513 (-) | 276 | WP_002217443.1 | hypothetical protein | - |
| A6L33_RS01685 (A6L33_01685) | - | 306510..306935 (-) | 426 | WP_002220721.1 | hypothetical protein | - |
| A6L33_RS01690 (A6L33_01690) | - | 306999..307370 (-) | 372 | WP_002220720.1 | hypothetical protein | - |
| A6L33_RS14585 | - | 307438..307644 (-) | 207 | WP_002217448.1 | hypothetical protein | - |
| A6L33_RS01695 (A6L33_01695) | - | 307661..308107 (-) | 447 | WP_002220718.1 | hypothetical protein | - |
| A6L33_RS01700 (A6L33_01700) | gpJ | 308178..312443 (-) | 4266 | WP_002220717.1 | TipJ family phage tail tip protein | - |
| A6L33_RS01705 (A6L33_01705) | - | 312579..313301 (-) | 723 | WP_002220716.1 | tail assembly protein | - |
| A6L33_RS01710 (A6L33_01710) | - | 313298..314053 (-) | 756 | WP_002244525.1 | C40 family peptidase | - |
| A6L33_RS01715 (A6L33_01715) | - | 314050..314772 (-) | 723 | WP_002217456.1 | phage minor tail protein L | - |
| A6L33_RS01720 (A6L33_01720) | - | 314832..315101 (-) | 270 | WP_002217457.1 | phage tail protein | - |
| A6L33_RS01725 (A6L33_01725) | - | 315123..318341 (-) | 3219 | WP_002224445.1 | phage tail length tape measure family protein | - |
| A6L33_RS01730 (A6L33_01730) | - | 318334..318606 (-) | 273 | WP_002220710.1 | DUF1799 domain-containing protein | - |
| A6L33_RS01735 (A6L33_01735) | - | 318654..318965 (-) | 312 | WP_002220709.1 | phage tail assembly chaperone | - |
| A6L33_RS01740 (A6L33_01740) | - | 319029..319670 (-) | 642 | WP_002220708.1 | phage tail protein | - |
| A6L33_RS01745 (A6L33_01745) | - | 319702..320121 (-) | 420 | WP_002244524.1 | hypothetical protein | - |
| A6L33_RS01750 (A6L33_01750) | - | 320102..320404 (-) | 303 | WP_002244523.1 | head-tail joining protein | - |
| A6L33_RS01755 (A6L33_01755) | - | 320397..320624 (-) | 228 | WP_002220705.1 | hypothetical protein | - |
| A6L33_RS01760 (A6L33_01760) | - | 320682..322574 (-) | 1893 | WP_002220704.1 | phage major capsid protein | - |
| A6L33_RS01765 (A6L33_01765) | - | 322555..324117 (-) | 1563 | WP_002220703.1 | phage portal protein | - |
| A6L33_RS01770 (A6L33_01770) | - | 324126..324380 (-) | 255 | WP_002220702.1 | hypothetical protein | - |
| A6L33_RS01775 (A6L33_01775) | - | 324367..324753 (-) | 387 | WP_002220701.1 | DUF3310 domain-containing protein | - |
| A6L33_RS01780 (A6L33_01780) | - | 324756..324965 (-) | 210 | WP_002220700.1 | hypothetical protein | - |
| A6L33_RS01785 (A6L33_01785) | - | 324982..327828 (-) | 2847 | WP_002220699.1 | primase-helicase family protein | - |
| A6L33_RS01790 (A6L33_01790) | - | 327943..328290 (-) | 348 | WP_002220698.1 | hypothetical protein | - |
| A6L33_RS01795 (A6L33_01795) | - | 328690..329406 (+) | 717 | WP_002220696.1 | LexA family transcriptional regulator | - |
| A6L33_RS01800 (A6L33_01800) | - | 329509..329934 (+) | 426 | WP_002220695.1 | hypothetical protein | - |
| A6L33_RS01805 (A6L33_01805) | - | 330165..330365 (+) | 201 | WP_002219431.1 | hypothetical protein | - |
| A6L33_RS01810 (A6L33_01810) | - | 330433..330792 (+) | 360 | WP_002220694.1 | hypothetical protein | - |
| A6L33_RS01815 (A6L33_01815) | - | 330817..331671 (+) | 855 | WP_002220693.1 | YfdQ family protein | - |
| A6L33_RS01820 (A6L33_01820) | - | 331743..331958 (+) | 216 | WP_002220692.1 | hypothetical protein | - |
| A6L33_RS01825 (A6L33_01825) | - | 331994..332254 (+) | 261 | WP_002220690.1 | NGO1622 family putative holin | - |
| A6L33_RS01830 (A6L33_01830) | - | 332251..332544 (+) | 294 | WP_002220689.1 | hypothetical protein | - |
| A6L33_RS01835 (A6L33_01835) | - | 332547..332738 (+) | 192 | WP_002219435.1 | type ISP restriction/modification enzyme | - |
| A6L33_RS01840 (A6L33_01840) | - | 332738..332878 (+) | 141 | WP_002220688.1 | hypothetical protein | - |
| A6L33_RS01845 (A6L33_01845) | - | 332875..333084 (+) | 210 | WP_002220687.1 | hypothetical protein | - |
| A6L33_RS01850 (A6L33_01850) | - | 333142..334059 (-) | 918 | WP_002220686.1 | KilA-N domain-containing protein | - |
| A6L33_RS01855 (A6L33_01855) | - | 334927..335406 (-) | 480 | WP_002241413.1 | DUF4760 domain-containing protein | - |
| A6L33_RS01870 (A6L33_01870) | - | 335842..336222 (-) | 381 | WP_002220683.1 | type II toxin-antitoxin system PemK/MazF family toxin | - |
| A6L33_RS01875 (A6L33_01875) | - | 336377..337573 (-) | 1197 | WP_002224447.1 | tyrosine-type recombinase/integrase | - |
| A6L33_RS01890 (A6L33_01890) | yaaA | 338105..338884 (-) | 780 | WP_002220681.1 | peroxide stress protein YaaA | - |
| A6L33_RS14660 | - | 338933..339058 (-) | 126 | Protein_363 | IS5/IS1182 family transposase | - |
| A6L33_RS01895 (A6L33_01895) | dapC | 339146..340333 (-) | 1188 | WP_002220680.1 | succinyldiaminopimelate transaminase | - |
| A6L33_RS01900 (A6L33_01900) | dut | 340409..340861 (-) | 453 | WP_002220679.1 | dUTP diphosphatase | - |
| A6L33_RS01905 (A6L33_01905) | - | 341004..341432 (+) | 429 | Protein_366 | AzlC family ABC transporter permease | - |
| A6L33_RS01910 (A6L33_01910) | pilX | 343491..343964 (-) | 474 | WP_002248276.1 | PilX family type IV pilin | Machinery gene |
| A6L33_RS01915 (A6L33_01915) | pilK | 343969..344562 (-) | 594 | WP_002248275.1 | pilus assembly PilX family protein | Machinery gene |
| A6L33_RS01920 (A6L33_01920) | pilJ | 344541..345479 (-) | 939 | WP_002248274.1 | PilW family protein | Machinery gene |
| A6L33_RS01925 (A6L33_01925) | pilV | 345476..346087 (-) | 612 | WP_002248273.1 | type IV pilus modification protein PilV | Machinery gene |
| A6L33_RS01930 (A6L33_01930) | pilH | 346111..346788 (-) | 678 | WP_002248272.1 | GspH/FimT family pseudopilin | Machinery gene |
| A6L33_RS01935 (A6L33_01935) | dnaB | 346943..348349 (-) | 1407 | WP_002248271.1 | replicative DNA helicase | - |
| A6L33_RS01940 (A6L33_01940) | - | 348512..349099 (+) | 588 | WP_002220670.1 | superoxide dismutase | - |
| A6L33_RS01945 (A6L33_01945) | - | 349671..350180 (-) | 510 | WP_002213852.1 | isoprenylcysteine carboxyl methyltransferase family protein | - |
| A6L33_RS01950 (A6L33_01950) | - | 350512..350844 (-) | 333 | WP_002226445.1 | hypothetical protein | - |
| A6L33_RS14665 | - | 350889..350996 (-) | 108 | Protein_376 | IS5/IS1182 family transposase | - |
| A6L33_RS01955 (A6L33_01955) | cysT | 351135..351971 (+) | 837 | WP_002226446.1 | sulfate ABC transporter permease subunit CysT | - |
| A6L33_RS01960 (A6L33_01960) | cysW | 352226..353086 (+) | 861 | WP_002220668.1 | sulfate ABC transporter permease subunit CysW | - |
| A6L33_RS01965 (A6L33_01965) | - | 353083..354156 (+) | 1074 | WP_002220667.1 | sulfate/molybdate ABC transporter ATP-binding protein | - |
| A6L33_RS01970 (A6L33_01970) | ilvA | 354213..355739 (-) | 1527 | WP_002220666.1 | threonine ammonia-lyase, biosynthetic | - |
| A6L33_RS01975 (A6L33_01975) | - | 355887..357056 (+) | 1170 | WP_002244947.1 | D-alanyl-D-alanine carboxypeptidase family protein | - |
| A6L33_RS01980 (A6L33_01980) | - | 357181..357753 (-) | 573 | WP_002220664.1 | 50S ribosomal protein L25/general stress protein Ctc | - |
| A6L33_RS01985 (A6L33_01985) | - | 357820..358803 (-) | 984 | WP_002213870.1 | ribose-phosphate pyrophosphokinase | - |
Sequence
Protein
Download Length: 203 a.a. Molecular weight: 22100.14 Da Isoelectric Point: 4.8335
>NTDB_id=190816 A6L33_RS01925 WP_002248273.1 345476..346087(-) (pilV) [Neisseria meningitidis strain M22722]
MKNNDCFRLKDSQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYMRNHTLSAVDGDFAIDAIKTKAQLAEEQLKRFSYELKNALPDAAAIRYAVCKDSLGAAPTLSAGSTFSPNCDNKAN
GDTLIKVLWVNDSAGDSDIARTNLEVSGDNIVYTYQARVGGRE
MKNNDCFRLKDSQSGMALIEVLVAMLVLTIGILALLSVQLRTVASVREAETQTIVSQITQNLMEGMLMNPTIDSDSNKKN
YNLYMRNHTLSAVDGDFAIDAIKTKAQLAEEQLKRFSYELKNALPDAAAIRYAVCKDSLGAAPTLSAGSTFSPNCDNKAN
GDTLIKVLWVNDSAGDSDIARTNLEVSGDNIVYTYQARVGGRE
Nucleotide
Download Length: 612 bp
>NTDB_id=190816 A6L33_RS01925 WP_002248273.1 345476..346087(-) (pilV) [Neisseria meningitidis strain M22722]
ATGAAGAATAATGATTGCTTCCGCCTGAAAGATTCCCAGTCCGGTATGGCGCTGATAGAAGTCTTGGTTGCTATGCTCGT
TCTGACCATCGGTATTTTGGCGTTACTGTCTGTGCAGTTGCGGACAGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACATGAGAAACCATACACTATCAGCTGTGGATGGCGATTTTGCGATTGATGCCATAAAAACTAAGGCGCA
GTTGGCAGAGGAACAATTGAAGAGATTTAGTTATGAGCTGAAAAATGCCTTGCCGGATGCGGCAGCCATCCGTTACGCCG
TCTGCAAGGATTCGTTGGGTGCTGCGCCGACATTGTCCGCCGGCAGTACTTTTTCTCCAAATTGCGATAATAAGGCAAAC
GGAGATACTTTAATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATCGCCCGTACGAATCTTGAGGTGAG
CGGCGACAATATCGTATATACCTATCAGGCAAGGGTCGGAGGTCGGGAATGA
ATGAAGAATAATGATTGCTTCCGCCTGAAAGATTCCCAGTCCGGTATGGCGCTGATAGAAGTCTTGGTTGCTATGCTCGT
TCTGACCATCGGTATTTTGGCGTTACTGTCTGTGCAGTTGCGGACAGTCGCTTCCGTCAGGGAGGCGGAGACACAAACCA
TCGTCAGCCAAATCACGCAAAACCTGATGGAAGGAATGTTGATGAATCCGACCATTGATTCGGACAGCAACAAGAAAAAC
TATAATCTTTACATGAGAAACCATACACTATCAGCTGTGGATGGCGATTTTGCGATTGATGCCATAAAAACTAAGGCGCA
GTTGGCAGAGGAACAATTGAAGAGATTTAGTTATGAGCTGAAAAATGCCTTGCCGGATGCGGCAGCCATCCGTTACGCCG
TCTGCAAGGATTCGTTGGGTGCTGCGCCGACATTGTCCGCCGGCAGTACTTTTTCTCCAAATTGCGATAATAAGGCAAAC
GGAGATACTTTAATTAAAGTATTGTGGGTAAATGATTCGGCAGGGGATTCGGATATCGCCCGTACGAATCTTGAGGTGAG
CGGCGACAATATCGTATATACCTATCAGGCAAGGGTCGGAGGTCGGGAATGA
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| pilV | Neisseria meningitidis 8013 |
91.304 |
100 |
0.931 |
| pilI | Neisseria gonorrhoeae MS11 |
82.266 |
100 |
0.823 |
| pilV | Neisseria gonorrhoeae MS11 |
82.266 |
100 |
0.823 |