Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   B9N48_RS08905 Genome accession   NZ_CP021169
Coordinates   1696730..1698610 (+) Length   626 a.a.
NCBI ID   WP_086343850.1    Uniprot ID   -
Organism   Bacillus subtilis strain TLO3     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1691730..1703610
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  B9N48_RS08890 ymcA 1692766..1693197 (+) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator
  B9N48_RS08895 cotE 1693459..1694004 (+) 546 WP_003231833.1 outer spore coat protein CotE -
  B9N48_RS08900 hexA 1694138..1696714 (+) 2577 WP_003231832.1 DNA mismatch repair protein MutS Machinery gene
  B9N48_RS08905 hexB 1696730..1698610 (+) 1881 WP_086343850.1 DNA mismatch repair endonuclease MutL Machinery gene
  B9N48_RS08910 ymzD 1699009..1699464 (-) 456 WP_080481313.1 regulatory YrvL family protein -
  B9N48_RS08915 - 1699619..1700176 (-) 558 WP_086343851.1 hypothetical protein -
  B9N48_RS08920 pksA 1700297..1700914 (+) 618 WP_003231827.1 TetR/AcrR family transcriptional regulator -
  B9N48_RS08925 pksB 1701104..1701781 (+) 678 WP_003231824.1 MBL fold metallo-hydrolase -
  B9N48_RS08930 - 1701891..1702157 (+) 267 WP_144486628.1 hypothetical protein -
  B9N48_RS08935 fabD 1702154..1703020 (+) 867 WP_086343852.1 ACP S-malonyltransferase -

Sequence

Protein


Download         Length: 626 a.a.        Molecular weight: 70451.37 Da        Isoelectric Point: 5.6018

>NTDB_id=190777 B9N48_RS08905 WP_086343850.1 1696730..1698610(+) (hexB) [Bacillus subtilis strain TLO3]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKQQQLIPSAQVPKKSAPAIKNEQQFITFDEKPPEKKVPEKSTAPSYSPMKLSSVVKELVDVEEELPPLQFDAPPI
VDQEQTLEVSDVSEEQPETFEQECHEEQQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVGE
VEPEVQEMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDIK
KLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1881 bp        

>NTDB_id=190777 B9N48_RS08905 WP_086343850.1 1696730..1698610(+) (hexB) [Bacillus subtilis strain TLO3]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGCAAGCGAGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCTCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACAGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGAAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTCAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATACGTGACGGA
ATTAAAGATGTGTTTAAACAGCAGCAGCTGATTCCTAGTGCCCAGGTCCCGAAAAAATCAGCACCTGCCATCAAAAATGA
GCAGCAGTTTATAACCTTTGATGAAAAGCCTCCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGCCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCTGGTTGATGTGGAGGAAGAATTGCCTCCTCTCCAATTTGATGCTCCACCTATC
GTTGATCAGGAACAAACCCTTGAGGTGTCCGATGTTTCAGAAGAACAGCCTGAAACATTTGAGCAGGAATGCCATGAGGA
ACAGCAGCCAGCGTCTGAGCGGGTTCCAATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAAACG
AAAACGGCCTATATATTATCGACCAGCACGCCGCCCAAGAACGTATTAAATATGAGTACTTTCGTGAAAAGGTGGGGGAG
GTTGAGCCTGAGGTGCAGGAGATGATTGTACCGCTGACGTTCCACTACTCCACAAATGAGGCTTTGATTATTGAACAGCA
CAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGTTACATCGTCCGCTGCCACCCGGCCT
GGTTTCCAAAGGGAGAAGAAGCAGAGCTCATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATTAAA
AAACTCCGTGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGACGAAAT
CAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACCACT
CGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

MutL C terminal dimerisation domain (MutL_C)

(441-582)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

46.166

100

0.471

Multiple sequence alignment