Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   A6L46_RS14315 Genome accession   NZ_CP016660
Coordinates   2008100..2008564 (+) Length   154 a.a.
NCBI ID   WP_164967094.1    Uniprot ID   -
Organism   Neisseria meningitidis strain M22804     
Function   DNA binding (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 2008265..2016567 2008100..2008564 flank -299
IS/Tn 2009254..2009907 2008100..2008564 flank 690


Gene organization within MGE regions


Location: 2008100..2016567
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  A6L46_RS14315 (A6L46_10495) comE 2008100..2008564 (+) 465 WP_164967094.1 helix-hairpin-helix domain-containing protein Machinery gene
  A6L46_RS14570 - 2008676..2009134 (+) 459 WP_002234522.1 hypothetical protein -
  A6L46_RS10505 (A6L46_10505) - 2009254..2009907 (+) 654 WP_019742811.1 IS1595 family transposase -
  A6L46_RS10510 (A6L46_10510) - 2010072..2010281 (+) 210 Protein_1937 transposase -
  A6L46_RS10515 (A6L46_10515) - 2010263..2010520 (-) 258 WP_002231679.1 membrane protein -
  A6L46_RS14045 - 2010798..2011025 (+) 228 WP_153310284.1 hypothetical protein -
  A6L46_RS10525 (A6L46_10525) aroG 2011187..2012242 (+) 1056 WP_002212267.1 3-deoxy-7-phosphoheptulonate synthase AroG -
  A6L46_RS10530 (A6L46_10530) - 2012310..2012798 (+) 489 WP_002218701.1 dihydrofolate reductase -
  A6L46_RS10535 (A6L46_10535) - 2013148..2013624 (-) 477 WP_002231682.1 CYTH domain-containing protein -
  A6L46_RS10540 (A6L46_10540) - 2013636..2014064 (-) 429 WP_002212270.1 CopD family protein -
  A6L46_RS10550 (A6L46_10550) - 2014176..2014421 (+) 246 WP_002212272.1 hypothetical protein -
  A6L46_RS14670 (A6L46_10555) - 2016079..2016567 (+) 489 WP_002258458.1 hypothetical protein -

Sequence

Protein


Download         Length: 154 a.a.        Molecular weight: 16442.72 Da        Isoelectric Point: 10.7894

>NTDB_id=190719 A6L46_RS14315 WP_164967094.1 2008100..2008564(+) (comE) [Neisseria meningitidis strain M22804]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASLQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPALPAAKK

Nucleotide


Download         Length: 465 bp        

>NTDB_id=190719 A6L46_RS14315 WP_164967094.1 2008100..2008564(+) (comE) [Neisseria meningitidis strain M22804]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACCCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCTGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCGGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCCGTCGGCGCGCCCGCACCAAAAGGCCCAGCCAAACCGGCTCTGCCCGCAGCTAAAAAATAG

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(75-133)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734
  comE Neisseria gonorrhoeae MS11

92.623

79.221

0.734

Multiple sequence alignment