Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   CAH07_RS12045 Genome accession   NZ_CP021123
Coordinates   2333427..2335310 (-) Length   627 a.a.
NCBI ID   WP_029317806.1    Uniprot ID   -
Organism   Bacillus subtilis strain SEM-9     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 2328427..2340310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAH07_RS12015 (CAH07_11855) fabD 2329043..2329909 (-) 867 WP_101172446.1 ACP S-malonyltransferase -
  CAH07_RS12020 (CAH07_11860) - 2329906..2330172 (-) 267 WP_120363368.1 hypothetical protein -
  CAH07_RS12025 (CAH07_11865) pksB 2330282..2330959 (-) 678 WP_003231824.1 MBL fold metallo-hydrolase -
  CAH07_RS12030 (CAH07_11870) pksA 2331149..2331766 (-) 618 WP_003231827.1 TetR/AcrR family transcriptional regulator -
  CAH07_RS12035 (CAH07_11875) - 2331887..2332444 (+) 558 WP_003245720.1 hypothetical protein -
  CAH07_RS12040 (CAH07_11880) ymzD 2332572..2333027 (+) 456 WP_015252068.1 regulatory YrvL family protein -
  CAH07_RS12045 (CAH07_11885) hexB 2333427..2335310 (-) 1884 WP_029317806.1 DNA mismatch repair endonuclease MutL Machinery gene
  CAH07_RS12050 (CAH07_11890) hexA 2335326..2337902 (-) 2577 WP_029317805.1 DNA mismatch repair protein MutS Machinery gene
  CAH07_RS12055 (CAH07_11895) cotE 2338035..2338580 (-) 546 WP_003231833.1 outer spore coat protein CotE -
  CAH07_RS12060 (CAH07_11900) ymcA 2338834..2339265 (-) 432 WP_003231834.1 regulatory iron-sulfur-containing complex subunit RicA Regulator

Sequence

Protein


Download         Length: 627 a.a.        Molecular weight: 70458.40 Da        Isoelectric Point: 5.7662

>NTDB_id=190545 CAH07_RS12045 WP_029317806.1 2333427..2335310(-) (hexB) [Bacillus subtilis strain SEM-9]
MAKVIQLSDELSNKIAAGEVVERPASVVKELVENAIDADSTVIEIDIEEAGLASIRVLDNGEGMENEDCKRAFRRHATSK
IKDENDLFRVRTLGFRGEALPSIASVSHLEITTSTGEGAGTKLVLQGGNIISESRSSSRKGTEIVVSNLFFNTPARLKYM
KTVHTELGNITDVVNRIALAHPEVSIRLRHHGKNLLQTNGNGDVRHVLAAIYGTAVAKKMLPLHVSSLDFEVKGYIALPE
ITRASRNYMSSVVNGRYIKNFPLVKAVHEGYHTLLPIGRHPITFIEITMDPILVDVNVHPSKLEVRLSKETELHDLIRDG
IKDVFKHQQLIPSAQLPKKSAPVIKNEQQFITFDEKPPEKKVPEKSTASSYSPMKLSSVVKEPVDAEEELPPLQFDAPPI
VDQEQTIEVSDVSAEQPETFELECHEEQPQPASERVPIMYPIGQMHGTYILAQNENGLYIIDQHAAQERIKYEYFREKVG
EVEPEVQDMIVPLTFHYSTNEALIIEQHKQELESVGVFLESFGSNSYIVRCHPAWFPKGEEAELIEEIIQQVLDSKNIDI
KKLREEAAIMMSCKGSIKANRHLRNDEIKALLDDLRSTSDPFTCPHGRPIIIHHSTYEMEKMFKRVM

Nucleotide


Download         Length: 1884 bp        

>NTDB_id=190545 CAH07_RS12045 WP_029317806.1 2333427..2335310(-) (hexB) [Bacillus subtilis strain SEM-9]
GTGGCAAAAGTCATCCAGCTGTCAGATGAGCTTTCAAATAAAATAGCGGCGGGCGAGGTTGTGGAACGGCCCGCCTCAGT
CGTCAAAGAATTGGTGGAAAATGCGATCGACGCTGACAGCACAGTCATTGAAATCGATATTGAGGAAGCAGGCCTTGCAT
CCATTCGGGTCTTGGATAACGGCGAAGGAATGGAGAATGAAGATTGTAAGCGTGCTTTCCGCCGCCACGCAACGAGTAAA
ATAAAAGATGAAAATGATTTATTCAGGGTGAGAACGCTCGGTTTCAGGGGAGAAGCCCTGCCGAGTATCGCGTCAGTCTC
TCATCTGGAGATTACAACAAGCACTGGTGAAGGAGCTGGGACGAAGCTCGTCCTCCAAGGAGGAAACATCATTTCCGAAT
CGCGTTCCTCAAGCAGGAAGGGAACTGAAATTGTCGTTTCCAACCTGTTTTTTAACACACCGGCCCGTTTGAAATATATG
AAAACCGTTCATACAGAGCTTGGAAACATTACGGATGTGGTTAACCGTATTGCTCTGGCGCATCCAGAGGTATCGATCCG
CCTGCGCCATCATGGGAAAAACCTGCTTCAAACGAACGGAAACGGAGATGTGCGCCATGTACTGGCAGCGATTTACGGCA
CGGCTGTCGCCAAAAAAATGCTTCCGCTGCATGTGAGCTCCTTGGATTTTGAAGTAAAGGGATATATCGCCCTCCCAGAG
ATTACACGGGCGTCGAGGAACTATATGTCGTCTGTGGTCAATGGCCGTTACATTAAAAATTTCCCGCTCGTCAAAGCGGT
TCATGAAGGCTATCATACGCTTCTGCCGATCGGACGCCATCCGATTACTTTTATAGAAATTACGATGGACCCGATTTTAG
TCGATGTTAACGTGCATCCATCGAAGCTTGAGGTCCGGCTCAGCAAGGAAACAGAGCTTCATGACTTAATTCGCGATGGA
ATTAAAGATGTATTTAAACACCAGCAGCTGATTCCGAGTGCCCAGCTCCCGAAAAAATCGGCACCTGTAATCAAAAATGA
GCAGCAGTTCATAACCTTTGATGAAAAGCCTCCGGAAAAAAAAGTTCCGGAAAAATCGACTGCGTCATCTTATTCACCAA
TGAAGCTCAGCTCAGTCGTGAAAGAGCCGGTTGATGCGGAGGAAGAATTGCCACCTCTCCAATTTGATGCTCCTCCTATC
GTTGATCAGGAACAAACCATTGAGGTGTCCGATGTTTCAGCAGAACAGCCTGAAACATTTGAGCTGGAATGCCATGAGGA
ACAGCCGCAACCAGCGTCTGAGCGGGTTCCGATTATGTACCCGATCGGCCAGATGCACGGGACTTATATATTGGCACAAA
ACGAAAACGGCCTATATATTATCGACCAGCACGCTGCCCAAGAACGTATTAAATATGAGTACTTCCGTGAAAAGGTGGGG
GAGGTTGAGCCTGAGGTGCAGGATATGATTGTACCGCTGACATTCCACTACTCCACAAATGAGGCTTTGATTATTGAACA
GCACAAACAAGAGCTCGAAAGCGTCGGTGTCTTTTTAGAGTCATTCGGCTCTAACAGCTACATCGTCCGCTGCCACCCGG
CCTGGTTTCCAAAGGGAGAAGAAGCAGAGCTCATAGAAGAAATCATTCAGCAGGTGCTCGACTCCAAAAATATAGATATT
AAAAAACTCCGCGAGGAAGCGGCGATTATGATGAGCTGCAAAGGCTCCATCAAAGCAAATCGCCACCTCAGAAACGATGA
AATCAAAGCGCTTCTGGACGACCTCCGAAGCACATCAGACCCATTTACATGCCCGCACGGCCGCCCGATCATCATTCACC
ACTCGACATATGAGATGGAAAAGATGTTCAAACGCGTGATGTAG

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(209-324)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)

MutL C terminal dimerisation domain (MutL_C)

(442-583)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

45.497

100

0.467

Multiple sequence alignment