Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   CAH07_RS04290 Genome accession   NZ_CP021123
Coordinates   846000..846635 (+) Length   211 a.a.
NCBI ID   WP_003243201.1    Uniprot ID   O32197
Organism   Bacillus subtilis strain SEM-9     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 841000..851635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  CAH07_RS04265 (CAH07_04225) liaI 842127..842507 (+) 381 WP_003243447.1 cell envelope stress-induced membrane anchor protein LiaI -
  CAH07_RS04270 (CAH07_04230) liaH 842534..843211 (+) 678 WP_003243047.1 stress responsive protein LiaH -
  CAH07_RS04275 (CAH07_04235) liaG 843312..844184 (+) 873 WP_003244420.1 DUF4097 domain-containing protein -
  CAH07_RS04280 (CAH07_04240) liaF 844218..844943 (+) 726 WP_003242605.1 LiaRS two-component regulatory system accessory protein LiaF -
  CAH07_RS04285 (CAH07_04245) liaS 844940..846022 (+) 1083 WP_003244464.1 two-component system sensor histidine kinase LiaS -
  CAH07_RS04290 (CAH07_04250) vraR 846000..846635 (+) 636 WP_003243201.1 two-component system response regulator LiaR Regulator
  CAH07_RS04295 (CAH07_04255) gerAC 846643..847764 (-) 1122 WP_003243203.1 spore germination receptor protein GerAC -
  CAH07_RS04300 (CAH07_04260) gerAB 847761..848858 (-) 1098 WP_009968145.1 spore germination receptor protein GerAB -
  CAH07_RS04305 (CAH07_04265) gerAA 848827..850275 (-) 1449 WP_003243555.1 spore germination receptor protein GerAA -
  CAH07_RS04310 (CAH07_04270) yvzF 850393..850578 (+) 186 WP_003244599.1 YvzF family protein -

Sequence

Protein


Download         Length: 211 a.a.        Molecular weight: 23124.76 Da        Isoelectric Point: 4.9049

>NTDB_id=190495 CAH07_RS04290 WP_003243201.1 846000..846635(+) (vraR) [Bacillus subtilis strain SEM-9]
MIRVLLIDDHEMVRMGLAAFLEAQPDIEVIGEASDGSEGVRLAVELSPDVILMDLVMEGMDGIEATKQICRELSDPKIIV
LTSFIDDDKVYPVIEAGALSYLLKTSKAAEIADAIRAASKGEPKLESKVAGKVLSRLRHSGENALPHESLTKRELEILCL
IAEGKTNKEIGEELFITIKTVKTHITNILSKLDVSDRTQAAVYAHRNHLVN

Nucleotide


Download         Length: 636 bp        

>NTDB_id=190495 CAH07_RS04290 WP_003243201.1 846000..846635(+) (vraR) [Bacillus subtilis strain SEM-9]
GTGATTCGAGTATTATTGATTGATGATCATGAAATGGTCAGAATGGGGCTCGCGGCTTTTTTGGAGGCGCAGCCCGATAT
TGAAGTCATCGGCGAAGCATCGGACGGCAGCGAAGGTGTTCGGCTTGCTGTGGAACTGTCGCCTGATGTCATTTTAATGG
ACCTTGTCATGGAGGGCATGGATGGCATTGAAGCTACAAAGCAAATTTGCCGGGAGCTTTCCGACCCGAAAATTATTGTG
CTCACTAGCTTCATTGATGATGACAAAGTGTACCCGGTTATTGAAGCTGGCGCGCTCAGCTATCTGTTGAAAACCTCAAA
AGCGGCAGAAATCGCCGATGCCATCCGCGCCGCAAGCAAGGGAGAGCCGAAGCTGGAGTCAAAAGTGGCGGGAAAAGTAT
TATCCAGGCTGCGCCACTCAGGTGAAAACGCGCTCCCGCATGAATCGCTTACAAAACGGGAGCTCGAAATACTCTGCCTG
ATCGCAGAAGGAAAGACAAACAAAGAAATAGGCGAGGAACTGTTTATTACGATTAAAACAGTCAAAACACATATTACGAA
TATTTTATCAAAGCTGGATGTCAGTGACCGGACGCAGGCGGCGGTGTACGCACACCGAAATCATCTCGTGAATTAG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB O32197

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.857

99.526

0.526
  degU Bacillus subtilis subsp. subtilis str. 168

38.565

100

0.408